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Daiki Kobayashi, Nagato Kuriyama, Keita Hirano, Osamu Takahashi and Hiroshi Noto

study. First, our data contained only diabetes treatment status, so the types of medication were unknown. Certain medications, such as pioglitazone or metformin, may cause or prevent cancer ( 38 , 39 ). A recent meta-analysis reported that pioglitazone

Open access

Katica Bajuk Studen and Marija Pfeifer

development of hypertension, cardiovascular disease and abnormalities in glucose metabolism ( 43 , 44 , 45 ). A recent meta-analysis suggests that risk of OSA is increased in adult women with PCOS. It seems that central obesity, hyperandrogenemia and insulin

Open access

Yao Chen and Shu-ying Fang

investigated in PCOS patients until now. Relevant literatures of case–control researches and meta-analysis studies were searched from PubMed database or by citation search and reference lists of relevant articles. Relationships of the candidate genes with PCOS

Open access

Luminita Nicoleta Cima, Anca Colita and Simona Fica

.94–2.82 CI, confidence interval; DFS, disease-free survival; OR, odds ratio; POF, premature ovarian failure; PR, pregnancy rate; RCT, randomized clinical trials; RM, resumption of menses; RR, relative risk. The largest meta-analysis that provides

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Raymond J Rodgers, Jodie C Avery, Vivienne M Moore, Michael J Davies, Ricardo Azziz, Elisabet Stener-Victorin, Lisa J Moran, Sarah A Robertson, Nigel K Stepto, Robert J Norman and Helena J Teede

clamp techniques showed that 75% of lean and 95% of obese women had IR compared to weight-matched controls ( 17 ). This was supported by a meta-analysis of clamp studies in PCOS where IR is clearly increased independently of BMI, yet, it is exacerbated

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Philippe Thuillier, Nathalie Roudaut, Geneviève Crouzeix, Marie Cavarec, Philippe Robin, Ronan Abgral, Véronique Kerlan and Pierre-Yves Salaun

, explorations have to be discussed. In FDG PET–CT, TI may appear as a focal FDG uptake (fTI) or as diffuse thyroid uptake (dTI) of the thyroid parenchyma. A recent meta-analysis of thirty studies, mostly retrospective, found a prevalence of 1.6% and 2.1% for fTI

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Thozhukat Sathyapalan, Anne-Marie Coady, Eric S Kilpatrick and Stephen L Atkin

J Peto R Armitage J Baigent C. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis . Lancet 2008 371 117 – 125 . ( doi:10.1016/S0140-6736(08)60104-X

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Stefan Pilz, Armin Zittermann, Christian Trummer, Verena Theiler-Schwetz, Elisabeth Lerchbaum, Martin H Keppel, Martin R Grübler, Winfried März and Marlene Pandis

supplementation such as the Vitamin D Assessment (ViDA) Study in 5108 older individuals randomized to 2500 µg (100,000 IU) of vitamin D per month or placebo did not report on increased risk of fractures or falls ( 128 , 129 ). In line with this, a recent meta-analysis

Open access

T P McVeigh, R J Mulligan, U M McVeigh, P W Owens, N Miller, M Bell, F Sebag, C Guerin, D S Quill, J B Weidhaas, M J Kerin and A J Lowery

remained ill-defined. A recent meta-analysis has revisited the possibility of such an association and has confirmed the existence of, and quantified the increased co-occurrence of breast and differentiated thyroid cancer (DTC) ( 1 ). Both cancers occur

Open access

Malin Nylander, Signe Frøssing, Caroline Kistorp, Jens Faber and Sven O Skouby

endothelial dysfunction, which is associated with an increased risk of cardiovascular disease (CVD) ( 4 ). PCOS is associated with both CVD and venous thromboembolism (VTE). A recent meta-analysis found an odds ratio of 1.44 (1.13–1.84) for coronary heart