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questionnaire that included questions about a history of thyroid or autoimmune disease, family health history, medication history, and fertility history. The women’s last menstrual period, height, weight, and blood pressure and the number of gestational weeks
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represents an essential resource for genetic studies because of the consanguinity rate of >50%, the high fertility levels, and the territory’s geography that favor the genetic isolation of this region ( 16 ). In fact, the high incidence of homozygous
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chemerin at dose of 1, 10, or 100 nM significantly reduced hCG-induced testosterone secretion and inhibited the levels of 3β-HSD. In addition, recombinant chemerin also reduced the sperm quality of rooster, affecting fertility ( 20 ). These results indicate
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polycystic ovary syndrome patients with adrenal androgen excess . Fertility and Sterility 2004 81 126 – 1 31 . ( https://doi.org/10.1016/j.fertnstert.2003.07.008 ) 16 Koh J Lee E Han K Kim EK Son EJ Sohn YM Seo M Kwon MR Yoon JH Lee
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Fertility Societies (IFFS), London Womens Clinic, Myovant, Netherlands Organisation for Health Research and Development (ZonMW), Pantharei Bioscience, Partners Group, PregLem/Gideon Richter, Shieldler, Reproductive Biomedicine Online (RBMO), UpToDate. JSE
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, evaluation of surgical possibilities and future fertility potential as well as estimation of the potential risk of gonadal malignancy ( 6 , 8 ). Cultural factors and parental wishes also play an important role in decision-making. In addition, the presence of
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(including assessment of future fertility potential and malignancy risk) and implementation of personalised medical plans in accordance with current disease-specific consensus guidelines ( 8 ). Additionally, in the long term, accurate early diagnosis will
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.1210/jc.2005-1490 ) 20 Bergh C Carlsson B Olsson JH Selleskog U Hillensjo T. Regulation of androgen production in cultured human thecal cells by insulin-like growth factor I and insulin . Fertility and Sterility 1993 59 323
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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.jchromb.2005.11.009 ). 15 Erichsen MM Husebye ES Michelsen TM Dahl AA Løvås K . Sexuality and fertility in women with Addison's disease . Journal of Clinical Endocrinology and Metabolism 2010 95 4354 – 4360 . ( doi:10.1210/jc.2010-0445 ). 16
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pubertal and adult patients ( 7 , 8 , 9 , 10 ). Testicular histology in adults is variable ( 10 ) with no reports of male fertility. Fewer centres have reported on females with hypogonadism ( 8 , 11 , 14 , 15 ). Features include hypoplastic labia at