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comorbidity such as history of diabetes mellitus, gestational diabetes, past or present history of thyroid disease, vascular disease, chronic hypertension, renal disease, polycystic ovary syndrome, use of corticosteroids, β-blockers, β-agonists and other drugs
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The Leicester Biomedical Research Centre, Leicester and Loughborough, UK
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, use of corticosteroids, disabling physical or mental condition and inability to speak English. Participants were recruited (July 2012 to July 2013) from primary care as identified by Read codes in the electronic record, PCOS clinics in the local
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status translating into a generalized ICI-induced immune activation. Earlier, it has been shown that the improved outcome can be maintained despite the use of corticosteroids to treat irAEs ( 32 ). ICI treatment itself and possible endocrine AEs may
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controls had not received any immunomodulatory or corticosteroid drugs. The patients with type 2 diabetes and healthy controls were matched for age, sex, and BMI to ensure comparability. This study protocol was approved by the ethics committee of Tsinghua
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, steroid-induced diabetes, post-transplant diabetes, hepatitis, corticosteroid therapy, active neoplasia, and ongoing shift work. The participants were asked to follow a moderate diet without excess fat or alcohol intake, 24 h prior to the testing day
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Department of Clinical Medicine, University of Copenhagen, Denmark
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. 12 Liu D Ahmet A Ward L Krishnamoorthy P Mandelcorn ED Leigh R Brown JP Cohen A & Kim H . A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy . Allergy, Asthma, and Clinical
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transplant began taking GH replacement, modulator therapy, or corticosteroids treatment at any time prior to the end of follow-up were also excluded. OGTTs were performed between 2003 and 2013. All patients who reached 18 years of age and had their height
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://doi.org/10.1111/j.1365-2265.2011.04082.x ) 29 Dunn JF Nisula BC & Rodbard D . Transport of steroid hormones: binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma . Journal of
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-lowering treatment in patients with CS while awaiting curative surgery regardless of thromboprophylaxis, to decrease the risk of postoperative withdrawal syndrome. This might be beneficial for the postoperative VTE risk as the corticosteroid withdrawal syndrome is a
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adrenal dysfunction may lead to either a relatively lower corticosteroid concentration in the AV, lowered cortisol levels in general, or a blunted response to synacthen stimulation ( 18 ). Of particular relevance to patients with primary aldosteronism, the