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used various cortisol measurement techniques (morning plasma, salivary, post-dexamethasone suppression, 24-h urine) that assess distinct aspects of the hypothalamic–pituitary–axis. An emerging new technique that may also be of use is measurement of hair
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children . Epidemiology of Obesity in Children and Adolescents 2011 455 – 482 . 5 Rutters F La Fleur S Lemmens S Born J Martens M Adam T . The hypothalamic–pituitary-adrenal axis, obesity, and chronic stress exposure: foods and HPA axis
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, et al. Central noradrenaline transporter availability is linked with HPA axis responsiveness and copeptin in human obesity and non-obese controls . Stress 2019 22 93 – 102 . ( https://doi.org/10.1080/10253890.2018.1511698 ) 48 Slavich GM
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Division of Interventional Cognitive Neurology, Department of Neurology, Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
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disease and psychological depression . Journal of Physiology and Pharmacology 2006 57 ( Supplement 11 ) 5 – 29 . 14 Keller J Gomez R Williams G Lembke A Lazzeroni L Murphy GM Jr Schatzberg AF . HPA axis in major depression: cortisol
Faculty of Medicine, University of Basel, Basel, Switzerland
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Faculty of Medicine, University of Basel, Basel, Switzerland
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blood pressure and tissue perfusion, occurs in sepsis and in septic shock resulting in activation of counteracting mediators ( 13 , 14 ). This includes activation of the arginine vasopressin (AVP) on the hypothalamic–pituitary–adrenal (HPA) axis ( 15
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46.4%) over a mean follow-up of 74 months. In a similar study, Alexandriki and coworkers ( 39 ) reported that the absence of HPA axis recovery within 12 months post-surgery predicted sustained remission with specificity of 89.1% (at sensitivity of 64
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Introduction Glucocorticoid and androgen hormone measurements play a decisive role in the diagnosis and management of many disorders of the hypothalamic–pituitary–adrenal (HPA) axis and gonads. Examples include Addison's disease (AD), Cushing
Department of Research and Development, Växjö, Sweden
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Department of Research and Development, Växjö, Sweden
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functioning and quality of life, but also on somatic health due to metabolic, inflammatory, autonomic and hypothalamic–pituitary–adrenal (HPA) axis dysregulations ( 7 , 8 , 9 , 10 , 11 ). Longitudinal studies have shown that depression was associated with