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Andrea V Haas Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Paul N Hopkins Cardiovascular Genetics, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA

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Nancy J Brown Vanderbilt University Medical Center, Nashville, Tennessee, USA

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Luminita H Pojoga Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Jonathan S Williams Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Gail K Adler Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Gordon H Williams Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

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used various cortisol measurement techniques (morning plasma, salivary, post-dexamethasone suppression, 24-h urine) that assess distinct aspects of the hypothalamic–pituitary–axis. An emerging new technique that may also be of use is measurement of hair

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Mardia López-Alarcón Unidad de Investigación Médica en Nutrición, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, Mexico

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Jessie N Zurita-Cruz Unidad de Investigación Médica en Nutrición, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, Mexico

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Alonso Torres-Rodríguez Escuela Española de Desarrollo Transpersonal, Madrid, España

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Karla Bedia-Mejía Unidad de Investigación Médica en Nutrición, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, Mexico

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Manuel Pérez-Güemez Unidad de Investigación Médica en Nutrición, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, Mexico

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Leonel Jaramillo-Villanueva Departamento de Psiquiatría, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, Mexico

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Mario E Rendón-Macías Universidad Panamericana, Facultad de Ciencias de la Salud, Escuela de Medicina, México, Mexico

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Jose R Fernández Departments of Nutrition Sciences and Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, USA

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Patricia Martínez-Maroñas Escuela Española de Desarrollo Transpersonal, Madrid, España

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children . Epidemiology of Obesity in Children and Adolescents 2011 455 – 482 . 5 Rutters F La Fleur S Lemmens S Born J Martens M Adam T . The hypothalamic–pituitary-adrenal axis, obesity, and chronic stress exposure: foods and HPA axis

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Sun Fei Wuxi Medical College of Jiangnan University, Wuxi, China

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Min Liu Wuxi Maternity and Child Health Care Hospital, Wuxi, China

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Hu Shanshan Wuxi Maternity and Child Health Care Hospital, Wuxi, China

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Ruijie Xie Department of Microsurgery, University of South China, Hengyang, China

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Wu Danni Wuxi Medical College of Jiangnan University, Wuxi, China

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Zhou Ningying Wuxi Medical College of Jiangnan University, Wuxi, China

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, et al. Central noradrenaline transporter availability is linked with HPA axis responsiveness and copeptin in human obesity and non-obese controls . Stress 2019 22 93 – 102 . ( https://doi.org/10.1080/10253890.2018.1511698 ) 48 Slavich GM

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Lukas Engler Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Christian Adolf Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Daniel A Heinrich Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Anna-Katharine Brem Max-Planck-Institute of Psychiatry, Munich, Germany
Division of Interventional Cognitive Neurology, Department of Neurology, Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

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Anna Riester Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Anna Franke Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Felix Beuschlein Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Martin Reincke Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Axel Steiger Max-Planck-Institute of Psychiatry, Munich, Germany

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Heike Künzel Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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disease and psychological depression . Journal of Physiology and Pharmacology 2006 57 ( Supplement 11 ) 5 – 29 . 14 Keller J Gomez R Williams G Lembke A Lazzeroni L Murphy GM Jr Schatzberg AF . HPA axis in major depression: cortisol

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Milena Kloter Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland

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Claudia Gregoriano Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Ellen Haag Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland

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Alexander Kutz Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland

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Beat Mueller Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland

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Philipp Schuetz Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland

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blood pressure and tissue perfusion, occurs in sepsis and in septic shock resulting in activation of counteracting mediators ( 13 , 14 ). This includes activation of the arginine vasopressin (AVP) on the hypothalamic–pituitary–adrenal (HPA) axis ( 15

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Prachi Bansal Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Anurag Lila Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Manjunath Goroshi Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Swati Jadhav Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Nilesh Lomte Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Kunal Thakkar Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Atul Goel Department of Neurosurgery, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Abhidha Shah Department of Neurosurgery, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Shilpa Sankhe Department of Radiology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Naina Goel Department of Pathology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Neelam Jaguste Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Tushar Bandgar Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Nalini Shah Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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46.4%) over a mean follow-up of 74 months. In a similar study, Alexandriki and coworkers ( 39 ) reported that the absence of HPA axis recovery within 12 months post-surgery predicted sustained remission with specificity of 89.1% (at sensitivity of 64

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Paal Methlie Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway

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Steinar Hustad Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway

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Ralf Kellman Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway

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Bjørg Almås Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway

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Martina M Erichsen Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway

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Eystein S Husebye Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway

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Kristian Løvås Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway

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Introduction Glucocorticoid and androgen hormone measurements play a decisive role in the diagnosis and management of many disorders of the hypothalamic–pituitary–adrenal (HPA) axis and gonads. Examples include Addison's disease (AD), Cushing

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Eva O Melin Department of Clinical Sciences, Endocrinology and Diabetes, Lund University, Lund, Sweden
Department of Research and Development, Växjö, Sweden
Primary Care, Växjö, Sweden

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Jonatan Dereke Department of Clinical Sciences Lund, Diabetes Research Laboratory, Lund University, Lund, Sweden

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Maria Thunander Department of Clinical Sciences, Endocrinology and Diabetes, Lund University, Lund, Sweden
Department of Research and Development, Växjö, Sweden
Department of Internal Medicine, Endocrinology and Diabetes, Central Hospital, Växjö, Sweden

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Magnus Hillman Department of Clinical Sciences Lund, Diabetes Research Laboratory, Lund University, Lund, Sweden

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functioning and quality of life, but also on somatic health due to metabolic, inflammatory, autonomic and hypothalamic–pituitary–adrenal (HPA) axis dysregulations ( 7 , 8 , 9 , 10 , 11 ). Longitudinal studies have shown that depression was associated with

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