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Morten Winkler Møller, Marianne Skovsager Andersen, Christian Bonde Pedersen, Bjarne Winther Kristensen, and Frantz Rom Poulsen

). For other PAs, except prolactinomas, surgery is the first choice of treatment. The primary surgical technique has been transsphenoidal surgery since Hardy introduced surgical microscopes in 1962 ( 9 ). Further development of this technique has improved

Open access

Chao-bin He, Yu Zhang, Zhi-yuan Cai, and Xiao-jun Lin

small numbers of included patients and the absence of unified standards, it is still unclear how much benefit can be obtained from surgery for patients with metastatic PNETs. PNET is a heterogeneous group of tumors and differs both biologically and

Open access

Jülide Durmuşoğlu, Henri J L M Timmers, Pepijn van Houten, Johan F Langenhuijsen, Ad R M M Hermus, and Annenienke C van de Ven

incidence of VTE in patients with ACC since malignancy, abdominal surgery and chemotherapy are associated with VTE ( 13 , 14 ). In addition, hormonal excess of cortisol and androgens/estrogens are also associated with an increased risk of VTE ( 15 , 16

Open access

Eeva M Ryhänen, Ilkka Heiskanen, Harri Sintonen, Matti J Välimäki, Risto P Roine, and Camilla Schalin-Jäntti

Introduction The clinical presentation of primary hyperparathyroidism (PHPT) has changed during the last decades. The majority of patients are nowadays asymptomatic with only mild hypercalcaemia (1, 2, 3) . Surgery offers the only opportunity for

Open access

Agnieszka Bogusz, Svenja Boekhoff, Monika Warmuth-Metz, Gabriele Calaminus, Maria Eveslage, and Hermann L Müller

 + pHL significantly decreased between 1 and 3 years after surgery for the PEDQOL domains social functionality friends ( P  = 0.050) and family ( P  = 0.016). Decreased QoL was observed during further follow-up in CP with a + pHL when compared with CP

Open access

Raluca Maria Furnica, Muhammad Muddaththir Dusoruth, Alexandre Persu, Damien Gruson, Michel Mourad, and Dominique Maiter

testing, as these tumours carry a very high rate of germline mutations, up to 35–40% in recent series ( 9 , 10 , 11 ). Surgery represents the primary treatment of PPGL ( 2 , 3 ). Thanks to improvements in medical treatment, anaesthesia and surgical

Open access

Nidan Qiao

Introduction Cushing’s disease (CD) is a subtype of pituitary adenoma with hypercortisolism and presents a particular challenge to neurosurgeons. Transsphenoidal surgery (TS) has long been the standard of care for patients with CD ( 1 , 2

Open access

Samira M Sadowski, Emanuel Christ, Benoit Bédat, Attila Kollár, Wolfram Karenovics, Aurel Perren, Frédéric Triponez, and on behalf of the SwissNET registry

recommendations for best practice: Patients are staged according to the UICC 7th TNM classification and surgery is the recommended therapy of choice in localized disease. Techniques are lobectomy or sleeve resection, with a complete anatomic resection and

Open access

Eva Jakobsson Ung, Ann-Charlotte Olofsson, Ida Björkman, Tobias Hallén, Daniel S Olsson, Oskar Ragnarsson, Thomas Skoglund, Sofie Jakobsson, and Gudmundur Johannsson

Introduction Pituitary tumours are rare; for example, the annual incidence of non-functioning pituitary adenomas is 0.65–2.34 per 100,000 ( 1 , 2 , 3 ). Although most pituitary tumours are benign, patients often need to undergo surgery and

Open access

Richard P Steeds, Vandana Sagar, Shishir Shetty, Tessa Oelofse, Harjot Singh, Raheel Ahmad, Elizabeth Bradley, Rachel Moore, Suzanne Vickrage, Stacey Smith, Ivan Yim, Yasir S Elhassan, Hema Venkataraman, John Ayuk, Stephen Rooney, and Tahir Shah

be referred to a Cardiologist and seen every 6 months. Medical management of CHD Treatment of CHD should be multidisciplinary, as there are competing demands of both CHD and NET. In some patients, surgery for CHD may be the priority to