Endocrine Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK
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Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK
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Endocrine Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK
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capacity of rodent adrenal capsule nearly 80 years ago ( 4 ), the exact in vivo identity of adrenocortical stem cells (ACSCs) remains elusive. Adult mesenchymal stromal or stem cells (MSCs) have drawn significant interest among researchers in the stem
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Department of Health & Life Sciences, Charles R. Drew University of Medicine and Science, Los Angeles, California, USA
Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
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Department of Health & Life Sciences, Charles R. Drew University of Medicine and Science, Los Angeles, California, USA
Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
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muscle stem cells’, have a remarkable ability to regenerate after muscle injury and are responsible for compensation of muscle turnover caused by daily wear and tear. In this study, we expand our previous results and conclusions ( 11 , 12 ) by now
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Hematology Department, Fundeni Hospital, Bucharest, Romania
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Endocrine Department, Elias Hospital, Bucharest, Romania
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Introduction Hematopoietic stem cell transplantation (HSCT) is increasingly used for the treatment of both malignant and nonmalignant diseases. Survival after autologous/allogeneic HSCT is no longer the highest concern, as many patients
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Division of Haematology-Oncology and Stem Cell Transplantation, Children’s Hospital, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Edinburgh Royal Hospital for Sick Children, Edinburgh, UK
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Introduction Fertility in males is dependent on the presence of a germ cell population that is capable of developing into sperm in adulthood. However, the ability of spermatogonial stem cells (SSC) to give rise to sperm is dependent on the
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Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
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North American (ENA) KS- and high-grade SCA patient-derived induced pluripotent stem cells (iPSCs) ( 10 , 11 , 12 , 13 , 14 , 15 ). Here, we present the first iPSC-based disease-modeling study performed on KS patients from Saudi Arabia. Saudi Arabia
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Section of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
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Introduction Hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment for children with life-threatening hematological and immunological diseases, including high-risk leukemias, but late effects are becoming prevalent
Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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that thyroid hormones are essential regulators of cardiac regeneration across phylogeny. Thyroid hormones also promote CM differentiation and maturation. They have been widely used to induce maturation of CMs derived from mouse embryonic stem cells
Research Center for Translational Medicine, Cancer Stem Cell Institute, East Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China
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), particularly in liver metastasis ( 10 ). For this reason, sunitinib, a multi-targeted tyrosine kinase receptor inhibitor of VEGFR1-3, platelet-derived growth factor receptor, mast/stem cell growth factor receptor kit, proto-oncogene tyrosine-protein kinase
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Vita-Salute San Raffaele University, Milan, Italy
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variability of isolated human islets and the need for lifelong immunosuppression. Different approaches using stem cells to support islet survival and function are being explored in preclinical and clinical settings ( 5 ). Now, the most advanced strategies to
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
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Saint Vincent’s Clinical School, UNSW Sydney, Sydney, Australia
SydPath, Saint Vincent’s Hospital, Sydney, Australia
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Gene & Stem Cell Therapy Program Centenary Institute, The University of Sydney, Camperdown, New South Wales, Australia
Faculty of Medicine & Health, The University of Sydney, Camperdown, New South Wales, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
School of Medicine, University of Wollongong, New South Wales, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Department of Head & Neck Surgery, Liverpool Hospital, Liverpool, New South Wales, Australia
Department of Clinical Medicine, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
South West Sydney Clinical School, UNSW Sydney, Sydney, Australia
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-L1 upregulation occurred in parallel with the up- and down-regulation of the stem-cell-related CD44 and CD24 surface markers, respectively; this was also accompanied by a morphological change from tightly arranged epithelial-like cells to widely