International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Pediatric Endocrinology Clinic, Department of Pediatrics, Aretaeio Hospital, Nicosia, Cyprus
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Denmark
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cell function that are independent of adrenal androgens are needed in the management of this patient group. Insulin-like factor 3 (INSL3) is a peptide hormone secreted by the Leydig cells, and it appears to be a new clinical biomarker of Leydig cell
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associations among insulin autoantibodies, islet cell antibodies, and HLA DAQ1*0301-DQB1*0302 in siblings of patients with type 1 (insulin-dependent) diabetes mellitus. Belgian diabetes registry . Journal of Clinical Endocrinology and Metabolism 1994 78 1172
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role of salivary cortisol for the diagnosis of AI during the insulin tolerance test, the gold standard test for the diagnosis of AI. AI was defined by a peak serum cortisol level <500 nmol/L. It found that a salivary cortisol cut-off level of 13.3 nmol
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Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland
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with hyperinsulinemia ( 11 ). Therefore, the explanation of a higher tendency to T2DM in MACS could be connected as a causal link between hypercortisolism and insulin resistance ( 9 ). In previous studies, approximately one-third of MACS patients
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Department of Neurosurgery, Technical University Munich (TMU), Munich, Germany
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Medizinische Klinik Und Poliklinik III, University Hospital Carl Gustav Carus, Dresden, Germany
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Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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. Nevertheless, results have been largely unsatisfactory (reviewed in ( 10 , 11 )). Linsitinib, a dual inhibitor of the insulin-like growth factor 1 receptor (IGF1R) and insulin receptor (IR), is the only targeted drug to have entered a phase III trial for ACC
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androgen excess, insulin resistance, and anovulation, like patients with non-classic CAH. It is important to rule out a diagnosis of non-classic CAH in patients with the diagnosis of PCOS, due to the divergent therapy and the genetic implications pre
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Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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. Maternal stress Prenatal maternal stress has been linked with long-term changes in the immune system in the offspring, including increases in pro-inflammatory cytokines such as TNF-α ( 84 ), as well as higher insulin levels and BMI ( 85 ), altered DNA
Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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history included levothyroxine 200 µg once daily, 3-monthly vitamin B12 injections, an actrapid/glargine basal bolus insulin regimen and the combined oral contraceptive pill (COCP). Eight years previously, she had been hospitalised for an episode of
IRCCS, Istituto Auxologico Italiano, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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included categories ‘insulin resistance’, ‘dyslipidaemia’, ‘cardiovascular complications’ and ‘psychosis’, which are not shown because these same categories were not reported in the patient survey. In the patient survey, responses for the categories