Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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, 24 ). Our dataset does not have the power to examine risk factors for peroperative hemodynamic instability but while keeping this limitation in mind, it suggests that medical pretreatment with PBZ titrated to orthostatic hypotension reduces
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SDHB . High-power (A) and low-power (B) H&E staining images of metastatic pheochromocytoma deposits in the iliac and peri-vesicular lymph nodes at presentation. CT (C) and PET-CT (D) images showing metastatic deposits of pheochromocytoma in the pelvic
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-squaretest was used for association analyses on 2 × 2 and 2 × 3 contingency tables. Two-tailed P values <0.05 were considered statistically significant. The power of the study was evaluated by means of the online PS power and sample size calculator v.2
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consistently recognized as factors with significant prognostic power in most studies, although an interobserver variation of Ki67 was found in previous studies ( 9 , 18 , 19 ). According to a meta-analysis, the higher mortality risk of cortisol-secreting ACC
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Wellcome–MRC Institute of Metabolic Science, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK
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contributing to the excess polar metabolite in this cohort but could also be due to the limited power of the study to detect a renal threshold effect or due to the shortcomings of eGFR as a marker of renal function ( 29 ). Nonetheless, we believe our findings
University of Alcalá, Madrid, Spain
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. Nevertheless, the retrospective design is a limitation that reduces the possibility of drawing conclusions in terms of causality. Another weakness of the study is the fact that only a minority of patients underwent AVS, which limits the power to determine if
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Supplements 2015 17 ( Supplement D ) D2 – D8 . ( https://doi.org/10.1093/eurheartj/suv035 ) 43 Cox JL & Pieper K . Harnessing the power of real-life data . European Heart Journal Supplements 2015 17 ( Supplement D ) D9 – D14 . ( https://doi.org/10
Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
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Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, España
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Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
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Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
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Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
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some of the variables used in the subanalyses, thereby reducing statistical power and impoverishing the interpretation of results. Second, the prescription of drugs that could cause SIAD was not registered. The main strength of our study is that we
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Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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statistical power to split the groups by sex. Interestingly, the healthy first-trimester DEX-treated subjects ( n = 9 women, 10 men) also had enlargement of the bilateral amygdala, larger surface area of the left superior frontal gyrus and alterations in