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Open access

Kathrin Zopf, Kathrin R Frey, Tina Kienitz, Manfred Ventz, Britta Bauer, and Marcus Quinkler

dose of hydrocortisone was lowered in recent years to an average of 20 mg per day. Failure of dose adaptations in situations with a high need for glucocorticoids is likely to lead to adrenal crisis (AC), which is a major threat to patients with AI ( 14

Open access

Stephanie Burger-Stritt, Linda Bachmann, Max Kurlbaum, and Stefanie Hahner

patients with primary AI ( 3 ). The relative risk of death from infectious disease compared to the background population was 6.6 in a Swedish analysis ( 1 ). Patients with chronic AI are at risk of adrenal crisis (AC) which contributes to the increased

Open access

Wiebke Arlt and the Society for Endocrinology Clinical Committee

Introduction Acute adrenal insufficiency , also termed adrenal crisis , is a life-threatening endocrine emergency brought about by a lack of production of the adrenal hormone cortisol, the major glucocorticoid. Identifying patients at risk

Open access

Thabiso R P Mofokeng, Salem A Beshyah, Fazleh Mahomed, Kwazi C Z Ndlovu, and Ian L Ross

236 (85.5) 54 (98.2) 291 (87.6, 83.6–90.8) Reference  Rural 40 (14.5) 1 (1.8) 0.006 41 (12.4, 9.2–16.4) <0.001 Experience managing adrenal crisis  No patients 154 (55.8) 25 (45.4) 0.160 179 (54.1, 48

Open access

Lia Ferreira, João Silva, Susana Garrido, Carlos Bello, Diana Oliveira, Hélder Simões, Isabel Paiva, Joana Guimarães, Marta Ferreira, Teresa Pereira, Rita Bettencourt-Silva, Ana Filipa Martins, Tiago Silva, Vera Fernandes, Maria Lopes Pereira, and Adrenal Tumors Study Group of the Portuguese Society of Endocrinology

hospitalization due to adrenal crisis through the review of all hospital medical records since the diagnosis. Adrenal crisis (AC) was defined as an acute impairment of general health requiring hospital admission and administration of intravenous saline and

Open access

Marie Freel

, or not-for-profit sector. References 1 Arlt W The Society for Endocrinology Clinical Committee. SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Emergency management of acute adrenal insufficiency (adrenal crisis) in adult

Open access

C E Higham, A Olsson-Brown, P Carroll, T Cooksley, J Larkin, P Lorigan, D Morganstein, P J Trainer, and the Society for Endocrinology Clinical Committee

( 19 ). If myxedema secondary to hypothyroidism is suspected, specialist endocrine input should be sought. Thyroxine should never be instigated unless cortisol deficiency is excluded as it can trigger an adrenal crisis. If in doubt, treat for

Open access

Salem A Beshyah, Khawla F Ali, and Hussein F Saadi

their usual dose if they feel symptoms of under replacement, I warn my patients to break the fast and seek emergency help if they experience symptoms of the impending adrenal crisis.) a The initial question confirms consent with the choices

Open access

S E Baldeweg, S Ball, A Brooke, H K Gleeson, M J Levy, M Prentice, J Wass, and the Society for Endocrinology Clinical Committee

(adrenal crisis) in adult patients . Endocrine Connections 2016 5 G1 – G3 . ( ) 10.1530/EC-16-0054) 4 Ball S Barth J Levy M & Society for Endocrinology Clinical Committee . Society for Endocrinology

Open access

Marcus Quinkler, Bertil Ekman, Claudio Marelli, Sharif Uddin, Pierre Zelissen, Robert D Murray, and on behalf of the EU-AIR Investigators

retrospective epidemiological data indicate high mortality among patients with both PAI and SAI ( 25 , 26 , 27 , 28 ). Besides adrenal crisis ( 29 ) and infectious disease ( 26 ), cardiovascular disease shows a 2-fold increased risk for mortality in Swedish