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Department of Cell Biology and Anatomy, Department of Medicine, Turku PET Centre, Department of Radiology, Medical Imaging Centre of Southwest Finland, Department of Endocrinology, Abdominal Center: Endocrinology, Minerva Foundation Institute for Medical Research, Institute of Biomedicine, University of Turku, FI-20520 Turku, Finland
Department of Cell Biology and Anatomy, Department of Medicine, Turku PET Centre, Department of Radiology, Medical Imaging Centre of Southwest Finland, Department of Endocrinology, Abdominal Center: Endocrinology, Minerva Foundation Institute for Medical Research, Institute of Biomedicine, University of Turku, FI-20520 Turku, Finland
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Department of Cell Biology and Anatomy, Department of Medicine, Turku PET Centre, Department of Radiology, Medical Imaging Centre of Southwest Finland, Department of Endocrinology, Abdominal Center: Endocrinology, Minerva Foundation Institute for Medical Research, Institute of Biomedicine, University of Turku, FI-20520 Turku, Finland
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Department of Cell Biology and Anatomy, Department of Medicine, Turku PET Centre, Department of Radiology, Medical Imaging Centre of Southwest Finland, Department of Endocrinology, Abdominal Center: Endocrinology, Minerva Foundation Institute for Medical Research, Institute of Biomedicine, University of Turku, FI-20520 Turku, Finland
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rodent osteoblasts (10, 13, 14, 15) , osteoclast-like cells (16) and in primary human osteoblasts differentiated from bone marrow-derived mesenchymal stem cells (17) . In vitro , insulin signaling promotes osteoblast differentiation and OC expression
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, hyperthyroidism significantly affected the proliferative potential of human hematopoietic stem/progenitor cells by decreasing the expression of pro- and anti-apoptotic genes, such as B-cell lymphoma-2 (BCL-2), B-cell lymphoma-XL (BCL-xL), and BCL2-associated X
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Pediatric Endocrinology Clinic, Department of Pediatrics, Aretaeio Hospital, Nicosia, Cyprus
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Denmark
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from aberrant adrenal cells descended together with the testis during fetal life. However, lately, it has been hypothesized that TARTs stem from pluripotent cells as the tumors also have testicular features ( 5 ). Associations between high
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Istituto Auxologico Italiano, IRCCS, Division of Metabolic Diseases and Auxology, Piancavallo (VB), Italy
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Introduction The prevalence of childhood type 2 diabetes mellitus (T2DM) is rapidly increasing worldwide ( 1 ). T2DM is characterized by visceral obesity, insulin resistance and defective β-cell function. In children and adolescents, glucose
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therapeutic strategies aimed at reducing prostate cancer burden in obesity. Adipose tissue is a complex organ that consists of multiple cell types including adipocytes, adipocyte progenitor cells, mesenchymal stem cells, endothelial cells and various resident
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mature adipocytes are of mesenchymal origin. The adipose tissue also constitutes a reservoir of mesenchymal stem cells, which may serve as an alternative cell source to bone marrow for tissue engineering in humans and equids (13, 14) . White fat
Department of Public Health, Erasmus University Medical Center, Rotterdam, Netherlands
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Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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Netherlands Comprehensive Cancer Organisation, Utrecht, Netherlands
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Department of Epidemiology and Data Science, Amsterdam UMC, Amsterdam, Netherlands
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and enhance cell differentiation in intestinal cells. Furthermore, increased intracellular TH levels, through Dio3 depletion, significantly reduced the tumorigenic potential of colorectal stem cells ( 9 ). However, these results were obtained from
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Children’s Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Research Program for Clinical and Molecular Metabolism, University of Helsinki, Helsinki, Finland
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Folkhälsan Institute of Genetics, University of Helsinki, Helsinki, Finland
Children’s Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Research Program for Clinical and Molecular Metabolism, University of Helsinki, Helsinki, Finland
Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden
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stem cell (MSC) differentiation and for deposition of collagen type I in the ECM ( 15 , 16 ). Monoallelic pathogenic mutations in the fibronectin-1 gene ( FN1 ) were first identified in 2017 in patients with a subtype of SMD, namely SMD with corner
Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK
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Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
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Department of Hepatology and Liver Transplantation, University Hospitals Birmingham (Queen Elizabeth), NHS Hospitals Foundation Trust, Birmingham, UK
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injury, qVICs become activated and also give rise to aVICs to enable valve repair and remodelling to take place ( 4 ). The pVICs are valvular stem cells derived from various origins and are found in the bone marrow, circulation, and heart valve leaflet
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V Billin AN Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells . American Journal of Physiology: Endocrinology and Metabolism 2014