Search Results

You are looking at 61 - 70 of 738 items for :

Clear All
Karim Gariani Service of Endocrinology, Diabetes, Hypertension and Nutrition, Geneva University Hospitals, Geneva, Switzerland

Search for other papers by Karim Gariani in
Google Scholar
PubMed
Close
,
Pedro Marques-Vidal Departments of Medicine and Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland

Search for other papers by Pedro Marques-Vidal in
Google Scholar
PubMed
Close
,
Gérard Waeber Departments of Medicine and Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland

Search for other papers by Gérard Waeber in
Google Scholar
PubMed
Close
,
Peter Vollenweider Departments of Medicine and Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland

Search for other papers by Peter Vollenweider in
Google Scholar
PubMed
Close
, and
François R Jornayvaz Service of Endocrinology, Diabetes, Hypertension and Nutrition, Geneva University Hospitals, Geneva, Switzerland

Search for other papers by François R Jornayvaz in
Google Scholar
PubMed
Close

(TG) level, increased insulin resistance (IR) and a higher fasting plasma glucose ( 5 ). Patients with T2DM may exhibit evidence of subclinical hypercortisolism such as higher 24-h urine-free cortisol levels, higher plasma cortisol levels after

Open access
Melinda Kertész Department of Medicine and Nephrology-Diabetes Centre, Medical School, University of Pécs, Pécs, Baranya, Hungary

Search for other papers by Melinda Kertész in
Google Scholar
PubMed
Close
,
Szilárd Kun Department of Medicine and Nephrology-Diabetes Centre, Medical School, University of Pécs, Pécs, Baranya, Hungary

Search for other papers by Szilárd Kun in
Google Scholar
PubMed
Close
,
Eszter Sélley Department of Medicine and Nephrology-Diabetes Centre, Medical School, University of Pécs, Pécs, Baranya, Hungary

Search for other papers by Eszter Sélley in
Google Scholar
PubMed
Close
,
Zsuzsanna Nagy Department of Medicine and Nephrology-Diabetes Centre, Medical School, University of Pécs, Pécs, Baranya, Hungary

Search for other papers by Zsuzsanna Nagy in
Google Scholar
PubMed
Close
,
Tamás Kőszegi Department of Laboratory Medicine, Medical School, University of Pécs, Pécs, Baranya, Hungary

Search for other papers by Tamás Kőszegi in
Google Scholar
PubMed
Close
, and
István Wittmann Department of Medicine and Nephrology-Diabetes Centre, Medical School, University of Pécs, Pécs, Baranya, Hungary

Search for other papers by István Wittmann in
Google Scholar
PubMed
Close

Introduction Insulin resistance related to glucotoxicity and lipotoxicity is a well-described phenomenon ( 1 , 2 ). It is also known that in insulin-resistant patients other hormonal resistance may occur (e.g. resistance to leptin and FSH ( 3

Open access
Julia Modesto Vicente Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil

Search for other papers by Julia Modesto Vicente in
Google Scholar
PubMed
Close
,
Junia Carolina Santos-Silva Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil

Search for other papers by Junia Carolina Santos-Silva in
Google Scholar
PubMed
Close
,
Caio Jordão Teixeira Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil

Search for other papers by Caio Jordão Teixeira in
Google Scholar
PubMed
Close
,
Dailson Nogueira de Souza Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil

Search for other papers by Dailson Nogueira de Souza in
Google Scholar
PubMed
Close
,
Jean Franciesco Vettorazzi Department of Structural and Functional Biology, Institute of Biology, State University of Campinas, Campinas, Brazil

Search for other papers by Jean Franciesco Vettorazzi in
Google Scholar
PubMed
Close
,
Fabiola Sales Furtuoso Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil

Search for other papers by Fabiola Sales Furtuoso in
Google Scholar
PubMed
Close
,
Isabel Gouveia Adabo Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil

Search for other papers by Isabel Gouveia Adabo in
Google Scholar
PubMed
Close
,
Fabio Takeo Sato Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, State University of Campinas, Campinas, Brazil

Search for other papers by Fabio Takeo Sato in
Google Scholar
PubMed
Close
,
Marco Aurélio Ramirez Vinolo Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, State University of Campinas, Campinas, Brazil

Search for other papers by Marco Aurélio Ramirez Vinolo in
Google Scholar
PubMed
Close
,
Everardo Magalhães Carneiro Department of Structural and Functional Biology, Institute of Biology, State University of Campinas, Campinas, Brazil

Search for other papers by Everardo Magalhães Carneiro in
Google Scholar
PubMed
Close
,
Silvana Bordin Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil

Search for other papers by Silvana Bordin in
Google Scholar
PubMed
Close
, and
Gabriel Forato Anhê Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil

Search for other papers by Gabriel Forato Anhê in
Google Scholar
PubMed
Close

). Additional prospective data revealed that exclusive breastfeeding for at least 6 months presented increased insulin sensitivity as assessed by HOMA-IR index 3 years after delivery rather than increased pancreatic β-cell function as indicated by in vivo

Open access
Clemens Kamrath Center of Child and Adolescent Medicine, Justus Liebig University, Giessen, Germany

Search for other papers by Clemens Kamrath in
Google Scholar
PubMed
Close
,
Alexander Eckert German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
Institute of Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany

Search for other papers by Alexander Eckert in
Google Scholar
PubMed
Close
,
Birgit Rami-Merhar Department of Pediatrics and Adolescent Medicine, Medical University Vienna, Vienna, Austria

Search for other papers by Birgit Rami-Merhar in
Google Scholar
PubMed
Close
,
Sebastian Kummer Department of General Pediatrics, Neonatology and Pediatric Cardiology, Heinrich Heine University, Medical Faculty, Duesseldorf, Germany

Search for other papers by Sebastian Kummer in
Google Scholar
PubMed
Close
,
Martin Wabitsch Center for Rare Endocrine Diseases, Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Centre, Ulm, Germany

Search for other papers by Martin Wabitsch in
Google Scholar
PubMed
Close
,
Katharina Laubner Division of Endocrinology and Diabetology, Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany

Search for other papers by Katharina Laubner in
Google Scholar
PubMed
Close
,
Florian Kopp Forth Clinical Department of Medicine, Academic Teaching Hospital Augsburg, Augsburg, Germany

Search for other papers by Florian Kopp in
Google Scholar
PubMed
Close
,
Silvia Müther Center for Pediatric Diabetology, DRK-Kliniken-Berlin Westend, Berlin, Germany

Search for other papers by Silvia Müther in
Google Scholar
PubMed
Close
,
Steffen Mühldorfer Department for Gastroenterology, Endocrinology and Metabolic Diseases, Bayreuth University Hospital, Friedrich-Alexander University Erlangen-Nuremberg, Bayreuth, Germany

Search for other papers by Steffen Mühldorfer in
Google Scholar
PubMed
Close
, and
Reinhard W Holl German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
Institute of Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany

Search for other papers by Reinhard W Holl in
Google Scholar
PubMed
Close

Introduction Diabetes mellitus due to insulin resistance is among the most prevalent endocrine disorders. It is commonly associated with obesity and lifestyle factors but may also occur in a very rare and severe form in patients with defects

Open access
Rongpeng Gong Medical College, Qinghai University, Xining, People’s Republic of China

Search for other papers by Rongpeng Gong in
Google Scholar
PubMed
Close
,
Gang Luo College of Eco-Environmental Engineering, Qinghai University, Xining, People’s Republic of China

Search for other papers by Gang Luo in
Google Scholar
PubMed
Close
,
Mingxiang Wang Medical College, Qinghai University, Xining, People’s Republic of China

Search for other papers by Mingxiang Wang in
Google Scholar
PubMed
Close
,
Lingbo Ma Medical College, Qinghai University, Xining, People’s Republic of China

Search for other papers by Lingbo Ma in
Google Scholar
PubMed
Close
,
Shengnan Sun Medical College, Qinghai University, Xining, People’s Republic of China

Search for other papers by Shengnan Sun in
Google Scholar
PubMed
Close
, and
Xiaoxing Wei Medical College, Qinghai University, Xining, People’s Republic of China

Search for other papers by Xiaoxing Wei in
Google Scholar
PubMed
Close

Background Insulin resistance (IR) is the insensitivity to insulin in insulin-dependent organs and tissues ( 1 ). The clinical manifestation of IR is the failure to respond to increase in blood sugar, which is associated with metabolic

Open access
Monika Bilic Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada
Department of Nutritional Sciences, University of Toronto, Toronto, Canada

Search for other papers by Monika Bilic in
Google Scholar
PubMed
Close
,
Huma Qamar Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada
Department of Nutritional Sciences, University of Toronto, Toronto, Canada

Search for other papers by Huma Qamar in
Google Scholar
PubMed
Close
,
Akpevwe Onoyovwi Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada

Search for other papers by Akpevwe Onoyovwi in
Google Scholar
PubMed
Close
,
Jill Korsiak Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada

Search for other papers by Jill Korsiak in
Google Scholar
PubMed
Close
,
Eszter Papp Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada

Search for other papers by Eszter Papp in
Google Scholar
PubMed
Close
,
Abdullah Al Mahmud Nutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh

Search for other papers by Abdullah Al Mahmud in
Google Scholar
PubMed
Close
,
Rosanna Weksberg Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada
Molecular and Medical Genetics, University of Toronto, Toronto, Canada
Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, Canada

Search for other papers by Rosanna Weksberg in
Google Scholar
PubMed
Close
,
Alison D Gernand Department of Nutritional Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA

Search for other papers by Alison D Gernand in
Google Scholar
PubMed
Close
,
Jennifer Harrington Division of Endocrinology, Hospital for Sick Children, Toronto, Canada

Search for other papers by Jennifer Harrington in
Google Scholar
PubMed
Close
, and
Daniel E Roth Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada
Department of Nutritional Sciences, University of Toronto, Toronto, Canada
Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, Canada

Search for other papers by Daniel E Roth in
Google Scholar
PubMed
Close

improve growth-related outcomes. The insulin-like growth factor (IGF) axis includes several signal and binding proteins, many of which are under the regulation of growth hormone. IGF-I is the primary regulator of fetal growth, and its circulating

Open access
Chenmin Wei Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
Department of Endocrinology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

Search for other papers by Chenmin Wei in
Google Scholar
PubMed
Close
,
Zichen Zhang Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

Search for other papers by Zichen Zhang in
Google Scholar
PubMed
Close
,
Qi Fu Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

Search for other papers by Qi Fu in
Google Scholar
PubMed
Close
,
Yunqiang He Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

Search for other papers by Yunqiang He in
Google Scholar
PubMed
Close
,
Tao Yang Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

Search for other papers by Tao Yang in
Google Scholar
PubMed
Close
, and
Min Sun Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

Search for other papers by Min Sun in
Google Scholar
PubMed
Close

and decreased insulin biosynthesis and secretion) ( 1 , 2 ). Of these factors, ER and oxidative stress are well known to affect receptor‐signal transduction, gene expression, and ion channel transport and induce cell apoptosis and death ( 3 ). The

Open access
Werner F Blum University Children’s Hospital, Giessen, Germany

Search for other papers by Werner F Blum in
Google Scholar
PubMed
Close
,
Abdullah Alherbish Al Habib Medical Group, Riyadh, Saudi Arabia

Search for other papers by Abdullah Alherbish in
Google Scholar
PubMed
Close
,
Afaf Alsagheir King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

Search for other papers by Afaf Alsagheir in
Google Scholar
PubMed
Close
,
Ahmed El Awwa Department of Pediatric Endocrinology & Diabetes, Hamad Medical Center, Doha, Qatar

Search for other papers by Ahmed El Awwa in
Google Scholar
PubMed
Close
,
Walid Kaplan Tawam Hospital, Al Ain, UAE

Search for other papers by Walid Kaplan in
Google Scholar
PubMed
Close
,
Ekaterina Koledova Global Medical Affairs Endocrinology, Merck KGaA, Darmstadt, Germany

Search for other papers by Ekaterina Koledova in
Google Scholar
PubMed
Close
, and
Martin O Savage William Harvey Research Institute, Barts and the London School of Medicine & Dentistry, London, UK

Search for other papers by Martin O Savage in
Google Scholar
PubMed
Close

Introduction The growth hormone (GH)–insulin-like growth factor (IGF)-I axis is the principle endocrine system regulating linear growth in children ( 1 ). Linked to the nutritional status of the individual, GH is a potent stimulator of IGF

Open access
Yumei Zhai The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China

Search for other papers by Yumei Zhai in
Google Scholar
PubMed
Close
,
Haiming Fu Department of Clinical Laboratory, Baotou Maternal and Child Health Center, Baotou, Inner Mongolia Autonomous Region, P.R. China

Search for other papers by Haiming Fu in
Google Scholar
PubMed
Close
,
Yu Li The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China

Search for other papers by Yu Li in
Google Scholar
PubMed
Close
,
Siyuan Li The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China

Search for other papers by Siyuan Li in
Google Scholar
PubMed
Close
,
Wenchen Zhang The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China

Search for other papers by Wenchen Zhang in
Google Scholar
PubMed
Close
,
Jianwei Yue The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China

Search for other papers by Jianwei Yue in
Google Scholar
PubMed
Close
, and
Zichao Wang The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China

Search for other papers by Zichao Wang in
Google Scholar
PubMed
Close

crucial to mitigate associated disabilities and fatalities ( 5 ). Insulin resistance (IR) is a central factor in cardiovascular diseases ( 6 ). In hypertensive patients, IR not only exacerbates hypertension but also contributes to hypertension

Open access
Rongpeng Gong Medical College of Qinghai University, Xining, People’s Republic of China

Search for other papers by Rongpeng Gong in
Google Scholar
PubMed
Close
,
Yuanyuan Liu Medical College of Qinghai University, Xining, People’s Republic of China

Search for other papers by Yuanyuan Liu in
Google Scholar
PubMed
Close
,
Gang Luo Medical College of Qinghai University, Xining, People’s Republic of China

Search for other papers by Gang Luo in
Google Scholar
PubMed
Close
,
Jiahui Yin College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China

Search for other papers by Jiahui Yin in
Google Scholar
PubMed
Close
,
Zuomiao Xiao Department of Clinical Laboratory, The Affiliated Ganzhou Hospital of Nanchang University, Ganzhou, China

Search for other papers by Zuomiao Xiao in
Google Scholar
PubMed
Close
, and
Tianyang Hu Precision Medicine Center, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China

Search for other papers by Tianyang Hu in
Google Scholar
PubMed
Close

Background Insulin resistance (IR) is a systemic disorder of glucose metabolism that results in changes in multiple organs and insulin regulatory pathways ( 1 , 2 , 3 ). The clinical significance of IR has become clear over the past few

Open access