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were associated with the function and development of neuronal cells. An RNA-seq study showed that the proliferation of cells is the leading functional network in hypothalamic neural-progenitor/stem cells treated with Dex ( 49 ), thereby indicating the
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European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
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to tumor cell growth and motility by lysophosphatidic acid production. Journal of Cell Biology 2002 158 227 – 233 . ( https://doi.org/10.1083/jcb.200204026 ) 10 Lee D Suh DS Lee SC Tigyi GJ Kim JH . Role of autotaxin in cancer stem cells
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indicated by elevated levels of circulating pancreatic enzymes ( 56 , 57 , 58 ). In a recent experimental study with derivatives from human pluripotent stem cells, it was demonstrated that the high expression of ACE2 in β cells and consequently the high β
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Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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significant attention has also been given to the hypothesis of adrenal regeneration from adrenocortical stem cells (ACSCs). Rodent model studies have shown that ACSCs are present in the subcapsular region of the adrenal cortex and migrate centripetally
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Institute of Pediatrics, Nanjing Medical University, Nanjing, China
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Institute of Pediatrics, Nanjing Medical University, Nanjing, China
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Institute of Pediatrics, Nanjing Medical University, Nanjing, China
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transcripts as shown in Fig. 6D . Based on the previous study, the verified target of miR-23b-5p is high-mobility group box 2 ( Hmgb2 ) in myocardial tissues ( 52 ). However, Hmgb2 was observed with pro-adipogenic effect in mesenchymal stem cells ( 60
Aix Marseille University, INSERM, INRA, C2VN, Marseille, France
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Research Unit EA 3279 and Department of Public Health, Aix-Marseille University, Marseille, France
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Research Unit EA 3279 and Department of Public Health, Aix-Marseille University, Marseille, France
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Nutrition, Metabolic Diseases and Endocrinology Department, AP-HM, La Conception Hospital, Marseille, France
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Nutrition, Metabolic Diseases and Endocrinology Department, AP-HM, La Conception Hospital, Marseille, France
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before hematopoietic stem-cell transplantation, represents a major risk factor for developing MS and CVD ( 10 , 11 , 12 , 13 , 14 , 15 ). In the LEA cohort, MS was found in 18.9% of young adults (mean age 21 years) who had received TBI during
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, 167 , 168 , 169 , 170 , 171 , 172 ) ( Fig. 4A and B ). The effects also depend on the developmental stage of the adipocytes, whether the cytokine acts directly on the mesenchymal stem cell, on the early committed preadipocytes (brown, beige or
Postgraduation Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
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Postgraduation Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
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migration, invasion, epithelial-mesenchymal transition and stemness properties in prostate cancer cells through targeting Argonaute 2 . International Journal of Oncology 2014 45 362 – 372 . ( doi:10.3892/ijo.2014.2413 ) 10.3892/ijo.2014.2413 24805183
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telomere length corresponds to the telomere length of the stem cells and endothelial progenitor cells. Thus, the lymphocyte telomere length could be used as a biomarker of vessel ageing. Therefore, the telomere length measuring in easily accessible tissues
Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands
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Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands
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Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands
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survivors of acute lymphoblastic leukemia with a history of cranial irradiation ( 12 ), those treated with total body irradiation prior to hematopoietic stem cell transplantation and survivors of non-brain solid tumors of the head whose treatment included