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Universidad La Salle, Posgrado de la Facultad de Ciencias Químicas, Ciudad de México, México
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:100 (Santa Cruz Biotechnology); antibody against aromatase (GTX32456), rabbit polyclonal diluted 1:200 (GeneTex, Irvine, CA, USA); and antibody against HSD17β1, rabbit polyclonal diluted 1:200 (GeneTex). The secondary antibody used was Mach2 anti-rabbit HRP
Division of Endocrinology and Metabolism, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
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NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
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NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
National Institute for Health Research (NIHR) Health Protection Research Unit in Environmental Exposures and Health, Imperial College London, London, UK
Mohn Centre for Children’s Health and Wellbeing, Imperial College London, London, UK
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NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
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NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
National Institute for Health Research (NIHR) Health Protection Research Unit in Environmental Exposures and Health, Imperial College London, London, UK
Mohn Centre for Children’s Health and Wellbeing, Imperial College London, London, UK
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months by the same participant, only the first completed was used for analysis ( Fig. 1 ). The questionnaire asked participants to self-report secondary sexual characteristic development from 1 (development not started) to 4 (development completed). Scale
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tyrosine kinase receptor, is expressed in Rathke's pouch and ventral diencephalon in the developing human embryo (5) . PROKR2 is a G protein-coupled receptor essential for normal olfactory bulb development and sexual maturation in mice (6) , and it is
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Y Oto Y Itabashi H Shiraishi M Yoshino A Tanaka Y Obata K Murakami N et al . Testosterone replacement therapy to improve secondary sexual characteristics and body composition without adverse behavioral problems in adult male patients
Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
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Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK
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Centre for Endocrinology, William Harvey Research Institute, Barts and The London Medical School, Queen Mary University of London, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, UK
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Department of Paediatric Endocrinology, Makarios Children's Hospital, Nicosia, Cyprus
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Sussex Community NHS Trust, Brighton, UK
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Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
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The University of Dublin, Trinity College Dublin, Dublin, Republic of Ireland
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spermatogonia have been described ( 132 ), and this, in combination with the high rates of undescended testes and hypogonadism, is likely to contribute to this sub-fertility. Young people with PWS have relationships that may include sexual activity, and advice
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Serviço de Endocrinologia, Departamento de Endocrinologia, Faculdade de Medicina da Universidade do Porto, Al. Prof. Hernâni Monteiro, 4200-319 Porto, Portugal
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axis is active in utero and during the first year of life (185) . Afterwards, gonadotropin secretion is reduced until puberty, when sequential endocrine changes set in motion the development of secondary sexual characteristics that will lead to
Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden.
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overrepresentation of women with these types of endocrine characteristics in elite sports. Essential hyperandrogenism is one example of the latter that has received much attention in recent years. The present overview describes our current state of knowledge about
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Blast injury Infiltrative/granulomatous disease Langerhans cell histiocytosis Autoimmune hypophysitis (primary, secondary) Sarcoidosis Tuberculosis Wegener’s granulomatosis Amyloidosis
Department of Developmental and Cell Biology, University of California, Irvine, California, USA
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Department of Pharmaceutical Sciences, University of California, Irvine, California, USA
Department of Biomedical Engineering, University of California, Irvine, California, USA
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and secondary sexual characteristics during puberty . International Journal of Hygiene and Environmental Health 2015 218 603 – 615 . ( https://doi.org/10.1016/j.ijheh.2015.06.004 ) 134 Golden R Gandy J Vollmer G A review of the endocrine
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Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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related to sexual function may not be avoided and are frequently reported ( 15 ), even if surgery is performed at a later age ( 18 , 19 , 20 ). Alternatively, patients and parents may opt out of surgery. There is some indication that GC treatment alone