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Stine A Holmboe Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Ravi Jasuja Research Program in Men’s Health: Aging and Metabolism, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Brian Lawney Research Program in Men’s Health: Aging and Metabolism, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Lærke Priskorn Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Niels Joergensen Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Allan Linneberg Centre for Clinical Research and Prevention, Frederiksberg Hospital, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Tina Kold Jensen Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark

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Niels Erik Skakkebæk Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Anders Juul Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Anna-Maria Andersson Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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-related characteristics and tested using general linear regression models. To compare the predictive value of the three free testosterone algorithms in relation to cardiometabolic conditions, Cox proportional hazards models with age as the underlying time scale were

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0552
Volume/Issue:
Volume 10: Issue 2
Open access
Alessandra Gambineri Endocrinology Unit, Department of Medical and Surgical Sciences, St Orsola-Malpighi Hospital, Alma Mater University of Bologna, Bologna, Italy

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Carla Pelusi Endocrinology Unit, Department of Medical and Surgical Sciences, St Orsola-Malpighi Hospital, Alma Mater University of Bologna, Bologna, Italy

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tissues, particularly on adipose tissue. The sexual dimorphism of androgens in the pathophysiology of T2DM is emphasized. Sex hormone differences between the sexes Males and females produce the same steroid hormones in a similar way. Regarding

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0450
Volume/Issue:
Volume 8: Issue 1
Open access
Salma R Ali Developmental Endocrinology Research Group, Royal Hospital for Children, University of Glasgow, Glasgow, UK
Office for Rare Conditions, University of Glasgow, Glasgow, UK

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Melissa Gardner Susan B Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA

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Yiqiao Xin Health Economics and Health Technology Assessment, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK

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Stuart O’Toole Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK

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Martyn Flett Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK

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Boma Lee Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK

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Mairi Steven Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK

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David E Sandberg Susan B Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA

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S Faisal Ahmed Developmental Endocrinology Research Group, Royal Hospital for Children, University of Glasgow, Glasgow, UK
Office for Rare Conditions, University of Glasgow, Glasgow, UK

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) measures ( 20 ). The questionnaire items were derived from focus groups and interviews involving clinicians with DSD expertise and parents of children with a disorders of sexual development (DSD). The parent self-report (PSR) questionnaire (for parents of

Article Type:
Research Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-24-0300
Volume/Issue:
Volume 13: Issue 11
Open access
Ping Gu Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

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Yuege Lin Department of Pathology, Nanjing Medical University, Nanjing, China

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Qi Wan Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

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Dongming Su Department of Pathology, Nanjing Medical University, Nanjing, China

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Qun Shu Department of Obstetrics, Shanghai First Maternity and Infant Health Hospital, School of Medicine, Tongji University, Shanghai, China

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). Recent reports have shown that oxytocin also contributes to maternal and sexual behaviors, bone formation, and metabolism ( 6 ). Strong evidence now also supports a relationship between oxytocin and diabetes; for example, Kujath et al. found lower

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0043
Volume/Issue:
Volume 10: Issue 7
Open access
Elena Valassi Endocrinology Department, Germans Trias i Pujol Hospital and Research Institute, Badalona, Barcelona, Spain
IRCCS, Istituto Auxologico Italiano, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy

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Iacopo Chiodini IRCCS, Istituto Auxologico Italiano, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy

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Richard A Feelders Division of Endocrinology, Erasmus Medical Centre, Rotterdam, Netherlands

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Cornelie D Andela Division of Endocrinology and Centre for Endocrine Tumours, Leiden University Medical Centre, Leiden, Netherlands

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Margueritta Abou-Hanna HRA Pharma Rare Diseases, Châtillon, France

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Sarah Idres HRA Pharma Rare Diseases, Châtillon, France

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Antoine Tabarin Department of Endocrinology and INSERM U862 University and CHU of Bordeaux, Pessac, France

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physicians. Methods Patient questionnaire design A 12-item patient questionnaire was developed based on the generally understood clinical characteristics and symptomology of CS, aiming to assess patients’ experiences of symptoms, diagnosis, care

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-22-0027
Volume/Issue:
Volume 11: Issue 7
Open access
D Santi Unit of Endocrinology, Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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A R M Granata Unit of Endocrinology, Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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M Simoni Unit of Endocrinology, Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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features of the selected studies. Table 1 Characteristics of studies included in the meta-analysis. References Number of treated patients Number of control patients Mean age (years) Baseline sperm concentration of treated patients (million/ml) Baseline

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-15-0050
Volume/Issue:
Volume 4: Issue 3
Open access
Antonia Ertelt Equine Clinic, Free University of Berlin, Berlin, Germany

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Ann-Kristin Barton Equine Clinic, Free University of Berlin, Berlin, Germany

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Robert R Schmitz Equine Clinic, Free University of Berlin, Berlin, Germany

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Heidrun Gehlen Equine Clinic, Free University of Berlin, Berlin, Germany

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present with a characteristic fat distribution showing deposits such as a cresty neck and at the comb, side of the chest, hip region, and tail head. Large omental fat deposits are also present, but not visible ( Fig. 1 ). Figure 1 Horse suffering from EMS

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-14-0038
Volume/Issue:
Volume 3: Issue 3
Open access
Paraskevi Kazakou Diabetes Centre, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Stavroula A Paschou Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Theodora Psaltopoulou Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Maria Gavriatopoulou Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Eleni Korompoki Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Katerina Stefanaki Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Fotini Kanouta Department of Endocrinology, Alexandra Hospital, Athens, Greece

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Georgia N Kassi Department of Endocrinology, Alexandra Hospital, Athens, Greece

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Meletios-Athanasios Dimopoulos Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Asimina Mitrakou Diabetes Centre, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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, 11 , 74 ). Survivors of the SARS outbreak after recovery presented mild secondary hypocortisolism (40%) or central hypothyroidism (5%). The potential underlying mechanisms may include edema and neuronal degeneration ( 74 ). Hyponatremia is prevalent

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-21-0184
Volume/Issue:
Volume 10: Issue 9
Open access
Frederic Schrøder Arendrup Department of Neurology, Danish Headache Center, Rigshospitalet, University of Copenhagen, Denmark

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Severine Mazaud-Guittot Inserm (Institut National de la Santé et de la Recherche Médicale), Irset – Inserm, UMR 1085, Rennes, France

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Bernard Jégou Inserm (Institut National de la Santé et de la Recherche Médicale), Irset – Inserm, UMR 1085, Rennes, France
EHESP-School of Public Health, Rennes, France

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David Møbjerg Kristensen Department of Neurology, Danish Headache Center, Rigshospitalet, University of Copenhagen, Denmark
Inserm (Institut National de la Santé et de la Recherche Médicale), Irset – Inserm, UMR 1085, Rennes, France

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Nanog that are characteristic for early embryonic stem cells ( 21 , 22 , 23 ). The exact nature of the migration related to proliferation is not clear; some evidence points to PGCs halting mitosis until colonizing the gonadal ridge ( 24 ), whereas

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0298
Volume/Issue:
Volume 7: Issue 1
Open access
Qiu-ming Yao Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China

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Bin Wang Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China

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Xiao-fei An Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China

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Jin-an Zhang Department of Endocrinology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China

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Liumei Ding Department of Clinical Laboratory, Jinshan Hospital of Fudan University, Shanghai, China

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characteristics We identified 572 articles from literature search ( Fig. 1 ). After reading titles and abstracts, most of them were excluded because some studies were not cohort or nested case-control studies or because the exposures or outcomes were not

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0253
Volume/Issue:
Volume 7: Issue 1
Open access