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Unit of Clinical Physiology, Karolinska University Hospital, Stockholm, Sweden
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Unit of Clinical Physiology, Karolinska University Hospital, Stockholm, Sweden
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Unit of Clinical Physiology, Karolinska University Hospital, Stockholm, Sweden
Unit of Cardiology, Karolinska University Hospital, Stockholm, Sweden
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Unit of Clinical Physiology, Karolinska University Hospital, Stockholm, Sweden
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satellite cell (SC) niche, i.e. myoblast stem cells ( 22 ). Adult skeletal muscle is terminally differentiated and in response to injury, a local pool of SCs situated beneath the basal lamina surrounding each myofibre proliferate ( 23 ). Their progeny
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Endocrinology and Diabetology Unit, Diabetology and Metabolic Disease Unit, Endocrinology Unit, Unit of Human Pathology, Surgical Department, Department of Clinical Sciences and Community Health, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pad.Granelli, Via F. Sforza, 35, 20122 Milan, Italy
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studies demonstrating that embryonic stem cells lacking PPARγ do not contribute to fat formation (28, 29) and that the abolishment of the expression of PPARγ at the adipose tissue level prevents WAT development (30, 31, 32) . In accordance with this
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. Angiogenesis in epithelian ovarian cancer . Molecular Pathology 2002 55 348 – 359 . 10.1136/mp.55.6.348 39 Markowska A Sajdak S Markowska J Huczynski A . Angiogenesis and cancer stem cells: new perspectives on therapy of ovarian cancer
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stem cells . Scientific Reports 2015 5 15280 . ( doi:10.1038/srep15280 ) 10.1038/srep15280 10 Sasaki T Lorkovic ZJ Liang SC Matzke AJ Matzke M . The ability to form homodimers is essential for RDM1 to function in RNA
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. Endocrine-Related Cancer 2011 18 491 – 503 . ( https://doi.org/10.1530/ERC-11-0102 7 Guo S Liu M Wang G Torroella-Kouri M Gonzalez-Perez RR . Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells
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. Cancer Research 2006 66 5707 – 5715 . ( doi:10.1158/0008-5472.CAN-05-4518 ) 32 Dor Y Brown J Martinez OI Melton DA. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation . Nature 2004
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Faculty of Medicine, University of Freiburg, Freiburg, Germany
Institute of Veterinary Medicine, Georg-August-University Goettingen, Goettingen, Germany
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. PNAS 1993 90 7578 – 7582 . ( https://doi.org/10.1073/pnas.90.16.7578 ) 30 Tanaka K Okamoto S Ishikawa Y Tamura H Hara T DDX1 is required for testicular tumorigenesis, partially through the transcriptional activation of 12p stem cell
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Department of Nephrology, School of Medicine, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
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Genetics 2010 696 – 706 . ( https://doi.org/10.1016/j.ajhg.2010.03.004 ) 42 Tsai RY McKay RD . A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells . Genes and Development 2002 2991 – 3003 . ( https
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Inserm (Institut National de la Santé et de la Recherche Médicale), Irset – Inserm, UMR 1085, Rennes, France
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( 1 , 19 ). PGCs are diploid stem cells responsible for giving rise to the germline in both males and females. Thus, they are the precursors of oocytes and spermatozoa in the ovaries and testes, respectively ( 20 ). PGCs arise in the extraembryonic
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recent progress facilitated by the TALEN, CRISPR/Cas9 or induced pluripotent stem cell (iPSCs) technologies, will promote, most likely, an acceleration of such models in the near future. Regarding SDH-deficient mouse models, the first homozygous KO of