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Klaus W Fagerstedt Department of Pathology, University of Helsinki, Helsinki, Finland

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Tom Böhling Department of Pathology, University of Helsinki, Helsinki, Finland
HUH Diagnostic Center and Helsinki University Hospital, Helsinki, Finland

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Harri Sihto Department of Pathology, University of Helsinki, Helsinki, Finland

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Tarja Salonen HUH Diagnostic Center and Helsinki University Hospital, Helsinki, Finland

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Fang Zhao Department of Pathology, University of Helsinki, Helsinki, Finland

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Mia Kero Department of Pathology, University of Helsinki, Helsinki, Finland
HUH Diagnostic Center and Helsinki University Hospital, Helsinki, Finland

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Leif C Andersson Department of Pathology, University of Helsinki, Helsinki, Finland

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Johanna Arola Department of Pathology, University of Helsinki, Helsinki, Finland
HUH Diagnostic Center and Helsinki University Hospital, Helsinki, Finland

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exocrine and endocrine portions of the tumor are derived from the bidirectional differentiation of a common stem cell ( 8 , 9 , 10 , 11 ). Stanniocalcin 1 (STC1) is a 56-kD homodimeric protein with autocrine and paracrine functions that protect cells

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Jiwen Yang Department of Nuclear Medicine, Yijishan Hospital of Wannan Medical College, Wuhu City, Anhui Province, China

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Yayin Huang Department of Clinical Laboratory, The Second People’s Hospital of Wuhu, Wuhu City, Anhui Province, China

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Bohan Dong Department of Biochemistry and Molecular Biology, Wannan Medical College, Wuhu City, Anhui Province, China

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Yunhai Dai Department of Nuclear Medicine, Yijishan Hospital of Wannan Medical College, Wuhu City, Anhui Province, China

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Xia JX Yao Y Zhou Q Long non-coding RNAs in stem cells and cancer . World Journal of Clinical Oncology 2014 5 134 – 141 . ( https://doi.org/10.5306/wjco.v5.i2.134 ) 4 Qiu MT Hu JW Yin R Xu L Long noncoding RNA: an emerging

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Tian Zhou School of Clinical Medicine, GuiZhou Medical University, Guiyang, Guizhou, China
Department of Breast Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China

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Dai-wei Zhao School of Clinical Medicine, GuiZhou Medical University, Guiyang, Guizhou, China
Department of Surgery, Second People's Hospital of Guizhou Province, Guiyang, Guizhou, China

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Ning Ma School of Clinical Medicine, GuiZhou Medical University, Guiyang, Guizhou, China

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Xue-ying Zhu School of Clinical Medicine, GuiZhou Medical University, Guiyang, Guizhou, China

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Xing-hong Chen Department of Surgery, Second People's Hospital of Guizhou Province, Guiyang, Guizhou, China

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Xue Luo Department of Breast Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China

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Song Chen School of Clinical Medicine, GuiZhou Medical University, Guiyang, Guizhou, China

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Qing-jun Gao Department of Thyroid Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China

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investigate PTC. In the present study, it was found that FOXP4 was highly expressed in THCA, and through the ROC curve analysis, it was suggested that FOXP4 might be used as a biomarker for diagnosing THCA. Currently, investigation on cancer stem cells shows

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Rocío del Carmen Bravo-Miana Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Departamento de Bioquímica Clínica, Córdoba, Argentina
Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Haya de la Torre y Medina Allende, Ciudad Universitaria, Córdoba (X5000HUA), Argentina

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Ana Belén Della Vedova Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Departamento de Bioquímica Clínica, Córdoba, Argentina
Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Haya de la Torre y Medina Allende, Ciudad Universitaria, Córdoba (X5000HUA), Argentina

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Ana Lucía De Paul Universidad Nacional de Córdoba, Facultad de Ciencias Médicas, Centro de Microscopía Electrónica, Córdoba, Argentina
Instituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET), Av. Enrique Barros y Enfermera Gordillo, Ciudad Universitaria, Córdoba, Argentina

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María Mónica Remedi Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Departamento de Bioquímica Clínica, Córdoba, Argentina
Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Haya de la Torre y Medina Allende, Ciudad Universitaria, Córdoba (X5000HUA), Argentina

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María Laura Guantay Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Departamento de Bioquímica Clínica, Córdoba, Argentina
Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Haya de la Torre y Medina Allende, Ciudad Universitaria, Córdoba (X5000HUA), Argentina

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Mónica Beatriz Gilardoni Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Departamento de Bioquímica Clínica, Córdoba, Argentina
Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Haya de la Torre y Medina Allende, Ciudad Universitaria, Córdoba (X5000HUA), Argentina

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Claudia Gabriela Pellizas Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Departamento de Bioquímica Clínica, Córdoba, Argentina
Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Haya de la Torre y Medina Allende, Ciudad Universitaria, Córdoba (X5000HUA), Argentina

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Ana Carolina Donadio Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Departamento de Bioquímica Clínica, Córdoba, Argentina
Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Haya de la Torre y Medina Allende, Ciudad Universitaria, Córdoba (X5000HUA), Argentina

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Desrochers LM Bordeleau F Reinhart-King CA Cerione RA Antonyak MA . Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation . Nature Communications 2016 7 11958 . ( https

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Meihua Jin Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Woo Kyung Lee Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

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Mi-Hyeon You Asan Institute of Life Science, Asan Medical Center, Seoul, Korea

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Ahreum Jang Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Sheue-yann Cheng Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

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Won Gu Kim Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Min Ji Jeon Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Yu-Mi Lee Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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(PHGDH), an important enzyme in serine biosynthesis, is associated with proliferation, tumorigenesis, and stemness of thyroid cancer cells ( 4 ). As PHGDH expression resulted in aggressive thyroid cancers, it might be a potential therapeutic target ( 4

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Masatada Watanabe Laboratory of Tissue Regeneration, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Shinagawa, Tokyo, Japan

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Shuji Ohno Division of Research for Pharmacy Students Education, Hoshi University, Shinagawa, Tokyo, Japan

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Hiroshi Wachi Laboratory of Tissue Regeneration, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Shinagawa, Tokyo, Japan

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mechanisms between cells of hematopoietic stem cell origin and cells of mesenchymal stem cell origin. This difference might provide a basis for new tissue-specific or cell-specific pharmacotherapeutic utilization of glucocorticoids, β-agonists and β

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Hong Tang Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China

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Xiaomei Jiang Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China

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Yu Hua Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China

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Heyue Li Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China

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Chunlan Zhu Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China

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Xiaobai Hao Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China

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Minhui Yi Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China

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Linxia Li Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China

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ubiquitination of TRAF3 ( 21 ). Laura Novellasdemunt et al. reported that NEDD4 and NEDD4L regulate Wnt signaling and intestinal stem cell priming by degrading the LGR5 receptor ( 33 ). In the current study, we found that GPX4 is the direct target of NEDD4L

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Juan Carlos Juárez-Cruz Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Miriam Daniela Zuñiga-Eulogio Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Monserrat Olea-Flores Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Eduardo Castañeda-Saucedo Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Miguel Ángel Mendoza-Catalán Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Carlos Ortuño-Pineda Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Ma Elena Moreno-Godínez Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Sócrates Villegas-Comonfort Instituto de Fisiología Celular, Universidad Nacional Autónoma de Mexico, Mexico City, México

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Teresita Padilla-Benavides Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA

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Napoleón Navarro-Tito Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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and therapeutic target of leptin signaling in breast cancer and cancer stem cells . Biochimica et Biophysica Acta 2013 207 – 222 . ( https://doi.org/10.1016/j.bbcan.2012.01.002 ) 12 Laudisio D Muscogiuri G Barrea L Savastano S Colao A

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Shikai Gui Department of Neurosurgery, the 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
Nanchang University, Nanchang, Jiangxi Province, China
Institute of Neuroscience, Nanchang University, Nanchang, Jiangxi Province, China

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Wanli Yu Department of Neurosurgery, the 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
Nanchang University, Nanchang, Jiangxi Province, China
Institute of Neuroscience, Nanchang University, Nanchang, Jiangxi Province, China

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Jiabao Xie Department of Neurosurgery, the 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
Nanchang University, Nanchang, Jiangxi Province, China
Institute of Neuroscience, Nanchang University, Nanchang, Jiangxi Province, China

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Lunshan Peng Department of Neurosurgery, the 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
Nanchang University, Nanchang, Jiangxi Province, China
Institute of Neuroscience, Nanchang University, Nanchang, Jiangxi Province, China

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Yuanyuan Xiong Department of Neurosurgery, the 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
Nanchang University, Nanchang, Jiangxi Province, China

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Zhen Song Nanchang University, Nanchang, Jiangxi Province, China
Department of Urology, the 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China

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Haitao Luo Department of Neurosurgery, the 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China

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Juexian Xiao Department of Neurosurgery, the 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China

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Shengtao Yuan Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, Nanjing, Jiangsu Province, China

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Zujue Cheng Department of Neurosurgery, the 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
Nanchang University, Nanchang, Jiangxi Province, China
Institute of Neuroscience, Nanchang University, Nanchang, Jiangxi Province, China

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Hematology and Oncology 2022 15 129 . ( https://doi.org/10.1186/s13045-022-01347-8 ) 33 Jin W . Role of JAK/STAT3 signaling in the regulation of metastasis, the transition of cancer stem cells, and chemoresistance of cancer by epithelial

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Zhandong Lei Key Laboratory of Cellular Physiology, Ministry of Education, and the Department of Physiology, Shanxi Medical University, Taiyuan, China
Department of Anatomy, Shanxi Medical University, Taiyuan, China

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Yunfei Chen Key Laboratory of Cellular Physiology, Ministry of Education, and the Department of Physiology, Shanxi Medical University, Taiyuan, China

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Jin Wang Key Laboratory of Cellular Physiology, Ministry of Education, and the Department of Physiology, Shanxi Medical University, Taiyuan, China

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Yan Zhang Key Laboratory of Cellular Physiology, Ministry of Education, and the Department of Physiology, Shanxi Medical University, Taiyuan, China

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Wenjuan Shi Key Laboratory of Cellular Physiology, Ministry of Education, and the Department of Physiology, Shanxi Medical University, Taiyuan, China

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Xuejiao Wang Key Laboratory of Cellular Physiology, Ministry of Education, and the Department of Physiology, Shanxi Medical University, Taiyuan, China

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Dehai Xing Key Laboratory of Cellular Physiology, Ministry of Education, and the Department of Physiology, Shanxi Medical University, Taiyuan, China

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Dongxue Li Key Laboratory of Cellular Physiology, Ministry of Education, and the Department of Physiology, Shanxi Medical University, Taiyuan, China

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Xiangying Jiao Key Laboratory of Cellular Physiology, Ministry of Education, and the Department of Physiology, Shanxi Medical University, Taiyuan, China

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Y Brown J Martinez OI Melton DA . Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation . Nature 2004 429 41 – 46 . ( https://doi.org/10.1038/nature02520 ) 6 Xu X D'Hoker J Stange G Bonne S

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