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Open access

T Grimmichova, M Haluzik, K Vondra, P Matucha, and M Hill

ultrasound-guided fine-needle aspiration ( 6 ). Finally, and the topic of our study, (8) type 2 diabetes (T2DM), obesity and insulin resistance (IR) in the framework of the worldwide epidemic of diabetes and obesity. In general, patients with diabetes have an

Open access

V Kenan Çelik, Sercan Kapancık, Turgut Kaçan, Selen Baloglu Kaçan, Serkan Kapancık, and Hasan Kılıçgün

, 24 ). According to our findings, decreased polyamine synthesis also affects spermine and spermidine concentrations; thus, a suspicion raises that it causes insulin resistance in type II diabetes as well. For this to be clear, there is a need for

Open access

Eliana Piantanida, Daniela Gallo, Giovanni Veronesi, Eugenia Dozio, Eugenia Trotti, Adriana Lai, Silvia Ippolito, Jessica Sabatino, Maria Laura Tanda, Antonio Toniolo, Marco Ferrario, and Luigi Bartalena

to calculate LDL cholesterol ( 37 ). FPG and insulin levels were used to calculate homeostatis model analysis of insulin resistance (HOMA-IR, normal value <2.5) and beta-cell function (HOMA-B, normal value <81.7). HOMA-IR was calculated according to

Open access

Benjamin Paul Green, Javier Thomas Gonzalez, Kevin Thomas, Emma Stevenson, and Penny Louise Sheena Rumbold

) , glucagon (3) , insulin (4) , and leptin (5) , among others, represent several commonly measured metabolic variables documented as key effectors targeting energy intake and expenditure. Accurate quantification of these peptides is therefore essential when

Open access

Henri Honka, Jukka Koffert, Saila Kauhanen, Nobuyuki Kudomi, Saija Hurme, Andrea Mari, Andreas Lindqvist, Nils Wierup, Riitta Parkkola, Leif Groop, and Pirjo Nuutila

assessment of insulin resistance; ISR, insulin secretion rate; OGIS, oral glucose insulin sensitivity index; VLDL-TAG, very-low density lipoprotein-triacylglycerol. Glucose, pancreatic and gut hormones during the mixed-meal test Incremental

Open access

Malin Nylander, Signe Frøssing, Caroline Kistorp, Jens Faber, and Sven O Skouby

and dyslipidemia, as well as insulin resistance ( 3 ). The abdominal obesity is characterized by a state of low-grade inflammation. Visceral adipose tissue secretes pro-inflammatory adipokines promoting an inflammatory state, contributing to

Open access

Giorgio Radetti, Mariacarolina Salerno, Chiara Guzzetti, Marco Cappa, Andrea Corrias, Alessandra Cassio, Graziano Cesaretti, Roberto Gastaldi, Mario Rotondi, Fiorenzo Lupi, Antonio Fanolla, Giovanna Weber, and Sandro Loche

clinical trials with l -T4 have shown no beneficial effect on the lipid profile in patients with subclinical hypothyroidism. Increased insulin resistance has also been described in some studies ( 19 , 20 , 21 ) but not in others ( 22 ). We believe that

Open access

Ali Abbasi

they did not measure a specific biomarker ( n =1) or investigated a measure of insulin resistance as the main exposure ( n =4). The characteristics of the 28 studies are summarized in Table 1 .The studies were performed in different populations; most

Open access

Line K Johnson, Kirsten B Holven, Njord Nordstrand, Jan R Mellembakken, Tom Tanbo, and Jøran Hjelmesæth

Introduction Women with polycystic ovarian syndrome (PCOS) are often overweight and have a central fat distribution (1) . It is well known that abdominal obesity is associated with insulin resistance, metabolic syndrome (MS) and increased risk of

Open access

Tingting Shu, Zhigang Lv, Yuchun Xie, Junming Tang, and Xuhua Mao

those in healthy individuals ( 7 , 9 , 10 ). However, the mechanism by which hepcidin mediates T2DM pathogenesis remains unclear. Recent reports attribute the probable mechanism to the induction of peripheral tissue insulin resistance ( 11 ) through