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Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany
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Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany
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) ratio in osteoblastic cells promotes osteoclastogenesis, inhibition of osteoblast differentiation, reduced matrix production, increased osteoblast and osteocyte apoptosis and increased autophagy further seem to contribute to GIO ( 5 , 6 , 7 , 8
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. Reactivated thyroid hormone receptor β attenuates anaplastic thyroid cancer (ATC) stem cell activity . Endocrine-Related Cancer 2023 30 e220306 . ( https://doi.org/10.1530/ERC-22-0306 ) 72 Kelly WK O'Connor OA Krug LM Chiao JH Heaney M Curley T
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insulin sensitivity and beta-cell function and subsequently glycaemic control. GLP-1 receptor agonists and dual hormone therapies have exhibited promising outcomes in those with T2D and obesity. Tirzepatide, a dual GLP-1 and GIP receptor agonist, has
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signaling pathways in osteoblasts, osteoclasts, and mesenchymal stem cells modulate the functional activity and differentiation fate of these cells; in general, increased catecholaminergic activity inhibits osteoblast function and enhances osteoclast
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, mesenchymal stem cells are also the precursor of marrow adipocytes, and the differentiation of these stem cells to these two cell lineages is competitive and reciprocally regulated ( 5 ). Bone marrow adiposity (BMA) itself is increasingly recognised to have a
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Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, People’s Republic of China
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