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Open access

Xiaoya Zheng, Shanshan Yu, Jian Long, Qiang Wei, Liping Liu, Chun Liu, and Wei Ren

Objective: Both primary thyroid lymphoma (PTL) and diffuse sclerosing variant of papillary thyroid carcinoma (DSVPTC) are two rare malignant tumours with different therapies and prognoses. This study compared their clinical features.

Methods: From a retrospective review of the pathologic database at our institute between January 2015 and August 2020, 52 PTL patients and 40 DSVPTC patients were included. Demographic, clinical, laboratory and ultrasound data were extracted from electronic medical records. Statistical analyses were performed using GraphPad Prism 5.0.

Results: Both PTL and DSVPTC were more likely to occur in women (83.7% and 67.5%), but DSVPTC patients were younger (median age: 36 vs 64.5), had fewer compressive symptoms, and more frequently had neck lymph node metastasis than PTL patients. The prevalence of Hashimoto’s thyroiditis (HT) and hypothyroidism was significantly higher in PTL patients than in DSVPTC patients (31% vs 17.5%). Hyperthyroidism could only be found in DSVPTC patients, which accounted for 7.5%. Heterogeneous echogenicity and irregular edges were frequently observed in both PTL and DSVPTC. However, compared with PTL, DSVPTC exhibited smaller lesion sizes, higher frequencies of diffuse sonographic patterns and calcification, and lower frequencies of hypoechoic features and internal blood flow signal. The overall survival rate with PTL was 77.23%, which was lower than that with DSVPTC (90.91%), but this difference was not significant (p=0.096).

Conclusion: Clinical characteristics such as age, compression symptoms, and sonographic features such as a large mass with heterogeneous echogenicity, hypoechoic, irregular edges, and calcification are helpful for impression diagnosis of PTL and DSVPTC before surgery.

Open access

Anping Su, Yanping Gong, Wenshuang Wu, Rixiang Gong, Zhihui Li, and Jingqiang Zhu

Introduction Total thyroidectomy with central neck dissection has been adopted in many specialized endocrine surgery units for the treatment of papillary thyroid carcinoma (PTC) ( 1 , 2 , 3 ). However, central neck dissection, especially

Open access

Logan Mills, Panagiotis Drymousis, Yogesh Vashist, Christoph Burdelski, Andreas Prachalias, Parthi Srinivasan, Krishna Menon, Corina Cotoi, Saboor Khan, Judith Cave, Thomas Armstrong, Martin O Weickert, Jakob Izbicki, Joerg Schrader, Andreja Frilling, John K Ramage, and Raj Srirajaskanthan

tumours ( 1 , 11 ). Variation and controversy exist as to the specific criteria used to select patients for surveillance, and as to the best strategy for using imaging for surveillance. The case for surgery in all non-functional tumours ≤2 cm does not

Open access

Wei Sun, Boyuan Zheng, Zhihong Wang, Wenwu Dong, Yuan Qin, and Hao Zhang

receive PCLND ( 9 ). In addition, dynamic observation of central lymph nodes is considered safe and should be performed for all patients with PTC before and during surgery to ensure that they are free from central neck metastasis ( 10 ). However, other

Open access

Dirk-Jan van Beek, Rachel S van Leeuwaarde, Carolina R C Pieterman, Menno R Vriens, Gerlof D Valk, and the DutchMEN Study Group

complications of surgery (e.g. hypoparathyroidism after (sub)total parathyroidectomy) and survival of dp-NETs as important topics since these affect quality of life. In a process of informed shared decision-making, research questions and study aims were

Open access

Danuta Gąsior-Perczak, Iwona Pałyga, Monika Szymonek, Artur Kowalik, Agnieszka Walczyk, Janusz Kopczyński, Katarzyna Lizis-Kolus, Anna Słuszniak, Janusz Słuszniak, Tomasz Łopatyński, Ryszard Mężyk, Stanisław Góźdź, and Aldona Kowalska

with a postoperative diagnosis of DTC underwent the first follow-up evaluation at 4–6 weeks after TT or L surgery. The procedures included a physical examination; neck ultrasound (US) and measurement of serum thyroid-stimulating hormone (TSH), Tg and

Open access

Stephanie E Baldeweg, Mark Vanderpump, Will Drake, Narendra Reddy, Andrew Markey, Gordon T Plant, Michael Powell, Saurabh Sinha, John Wass, and the Society for Endocrinology Clinical Committee

, major surgery, especially coronary artery bypass grafting, dynamic testing of the pituitary gland, anticoagulation therapy, coagulopathies, pregnancy and head trauma. Differential diagnosis SAH due to ruptured intracranial aneurysm or

Open access

C Sui, Q He, R Du, D Zhang, F Li, G Dionigi, N Liang, and H Sun

retrospective study was conducted in line with the STROCSS criteria ( 17 ). Setting The Thyroid Surgery Division in China-Japan Union Hospital of Jilin University is the largest referral and academic endocrine surgery center in the northeastern region of

Open access

Andrea Mazurat, Andrea Torroni, Jane Hendrickson-Rebizant, Harbinder Benning, Richard W Nason, and K Alok Pathak

reported. Funding This study was supported by the University of Manitoba Research Grant 2009 and the Department of Surgery, University of Manitoba Research Grant 2010. Author contribution statement K A Pathak and R W Nason involved in study concept and

Open access

Mubashir Mulla and Klaus-Martin Schulte

importance of a thorough preoperative evaluation and subsequent appropriate initial surgery has been emphasised in many studies (7, 36) . US is the most popular imaging modality used in preoperative evaluation of cervical LN in PTC and is recommended by ATA