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ADP, vaspin, and visfatin in the context of thyroid dysfunction and the associated changes in adipose tissue and insulin resistance. The reason for choosing them is the increasing evidence regarding their changes in states of thyroid dysfunction
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Department of Obstetrics and Gynaecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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several metabolic and cardiovascular health implications. Women with PCOS commonly suffer from chronic anovulation, infertility, hyperandrogenaemia, obesity, dyslipidaemia and low-grade chronic inflammation ( 2 ). Insulin resistance is a common feature of
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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(MSCC) and brain tumours. Diabetes mellitus (DM) is a well-known metabolic side effect from treatment with glucocorticoids. The diabetogenic effect is mainly a result of insulin resistance in muscle and fatty tissue, increased production of glucose from
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), cardiovascular disease (CVD) contributes to a two- to four-times higher death rate in patients with T1DM, compared with the general population ( 3 , 4 ). Diabetes Control and Complications Trials (DCCT) have exhibited that intensive insulin therapy attenuated
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Introduction GH regulates β-cell function (βCF) and insulin sensitivity (IS) both directly and via complex interactions with its principal mediator, insulin-like growth factor 1 (IGF1) (1) . While GH reduces IS, IGF1 increases it. The hyperglycemic
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exerted by obesity on cognitive dysfunction and vice versa. Both have been associated with morphological reductions in brain volume, relating to systemic dysmetabolism and insulin resistance and/or to the degree of cognitive impairment ( 21 , 22 , 23
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Introduction Gestational diabetes mellitus (GDM) is primarily resulted from insulin resistance and glucose intolerance during pregnancy, affecting 7% of pregnant women globally ( 1 , 2 ). GDM causes higher risks of diabetes, obesity and
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. This was highlighted in a scientific advisory committee (SACN) statement on nutrition that stated, although cereal fiber intake has been associated with a reduced incidence of type 2 diabetes (T2DM) and metabolic risk factors such as insulin resistance
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) , glucagon (3) , insulin (4) , and leptin (5) , among others, represent several commonly measured metabolic variables documented as key effectors targeting energy intake and expenditure. Accurate quantification of these peptides is therefore essential when
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the increase in the incidence of TN is related to some components of MS ( 7 ). Researchers in the field have found that MS and insulin resistance are important factors associated with the increased incidence of nodular goiter and thyroid cancer ( 8