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Stavroula A Paschou, Eleni Palioura, Dimitrios Ioannidis, Panagiotis Anagnostis, Argyro Panagiotakou, Vasiliki Loi, Georgios Karageorgos, Dimitrios G Goulis, and Andromachi Vryonidou

steroidogenesis to the total circulating steroid pool ( 23 ). In the present study, when a cohort of women with PCOS was classified into two subgroups according to DHEA-S concentrations, no significant difference was observed between them in insulin resistance

Open access

Davoud Jafari-Gharabaghlou, Mostafa Vaghari-Tabari, Hajar Oghbaei, Laura Lotz, Reza Zarezadeh, Yeganeh Rastgar Rezaei, Mahnaz Ranjkesh, Mohammad Nouri, Amir Fattahi, Saba Nikanfar, and Ralf Dittrich

present in the uterus and placenta where they can influence implantation and pregnancy as well as maternal–fetal transmission of metabolites ( 6 , 7 ). It has been demonstrated that various stages of implantation are profoundly regulated by steroids

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Huifei Sophia Zheng, Jeffrey G Daniel, Julia M Salamat, Laci Mackay, Chad D Foradori, Robert J Kemppainen, Satyanarayana R Pondugula, Ya-Xiong Tao, and Chen-Che Jeff Huang

catecholamine synthesis-associated genes were considered DEG, several genes associated with the regulation of neurotransmitter secretion (GO:0046928, fold enrichment of 4.0, FDR P = 0.000407) were included in the Dex-upregulated genes. Regarding steroid

Open access

Xiaomin Li, Ling Fang, Hongjiang Li, and Xiaoqin Yang

steroid ring of estrogen produces a cascade of metabolites with diverse biological properties, such as 2-hydroxyestrone (2-OHE1), 4-hydroxyestrone (4-OHE1), and 16α-hydroxyestrone (16α-OHE1). These hydroxylated metabolites can be further methylated into

Open access

Andrew R Dismukes, Vanessa J Meyer, Elizabeth A Shirtcliff, Katherine P Theall, Kyle C Esteves, and Stacy S Drury

Introduction Dehydroepiandrosterone (DHEA) is a steroid hormone that is sometimes called the ‘anti-aging hormone’ because of ts protective effects on memory, neuronal growth, and neuronal activity ( 1 ). DHEA is produced both centrally, as a

Open access

Gabriella Oliveira Lima, Alex Luiz Menezes da Silva, Julianne Elba Cunha Azevedo, Chirlene Pinheiro Nascimento, Luana Rodrigues Vieira, Akira Otake Hamoy, Luan Oliveira Ferreira, Verônica Regina Lobato Oliveira Bahia, Nilton Akio Muto, Dielly Catrina Favacho Lopes, and Moisés Hamoy

Povoroznyuk V Balatska N Barbosa AP Karonova T Vitamin D supplementation guidelines . Journal of Steroid Biochemistry and Molecular Biology 2018 175 125 – 135 . ( ) 10.1016/j.jsbmb.2017.01.021 5 Vieth R

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Elizabeth Yan Zhang and Bao-Ting Zhu

chromatography and GC–MS – II. Fractionation and quantitation of the main groups of estrogen conjugates . Journal of Steroid Biochemistry 1987 28 215 – 226 . ( doi:10.1016/0022-4731(87)90380-3 ). 21 Zhou R Lai Y Yamabe N Fukui M Zhu BT . Estriol

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Soraya Puglisi, Paola Perotti, Mattia Barbot, Paolo Cosio, Carla Scaroni, Antonio Stigliano, Pina Lardo, Valentina Morelli, Elisa Polledri, Iacopo Chiodini, Giuseppe Reimondo, Anna Pia, and Massimo Terzolo

effects associated to treatment were either directly related to the drug intake (nausea, vomiting, dizziness, sedation, headache) or secondary to the metyrapone-induced alteration of steroid synthesis (hirsutism, hypertension) ( 8 , 9 ). In patients

Open access

Gavin P Vinson and Caroline H Brennan

on mood and behaviour. Steroids in the brain The spectrum of structures and functions of neurosteroids is so wide as to form a branch of endocrinology (or at least paracrinology) in its own right. Many are locally synthesized, although usually

Open access

Sebastião Freitas de Medeiros, Cinthia Marenza Ormond, Matheus Antônio Souto de Medeiros, Nayara de Souza Santos, Camila Regis Banhara, and Márcia Marly Winck Yamamoto

sulfotransferase (SULT2 A1) drive these precursors toward the synthesis of ∆4 steroids and dehydroepiandrosterone sulfate (DHEAS), respectively ( 7 ). After exclusion of other hyperandrogenemic conditions such as hyperprolactinemia, thyroid dysfunction and the