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Anne-Sophie C A M Koning, Philippe C Habets, Marit Bogaards, Jan Kroon, Hanneke M van Santen, Judith M de Bont, and Onno C Meijer

expressed in the brain. They are members of the nuclear receptor family and act as transcriptional regulators. Activation by cortisol leads to translocation of the receptors from the cytoplasm to the cell nucleus and subsequent interaction with DNA and

Open access

Yusaku Mori, Hiroyuki Shimizu, Hideki Kushima, Tomomi Saito, Munenori Hiromura, Michishige Terasaki, Masakazu Koshibu, Hirokazu Ohtaki, and Tsutomu Hirano

the vasoprotective and vasopressor effects of nesfatin-1 at different doses in mouse models of peripheral arterial remodeling. Additionally, we sought to clarify the underlying mechanisms in cultured human vascular endothelial cells (VECs) and vascular

Open access

Yu Lin, Yingying Zhang, Lei Xu, Wei Long, Chunjian Shan, Hongjuan Ding, Lianghui You, Chun Zhao, and Zhonghua Shi

of adipogenesis ( 6 , 7 ), stem cell pluripotency ( 8 ), cancer ( 9 ), cell development and differentiation ( 10 , 11 ), etc. Cui et al. ( 12 ) demonstrated that the transcribed ultraconserved lncRNA, uc.417, could serve as a negative regulator of

Open access

Shuang Ye, Yuanyuan Xu, Jiehao Li, Shuhui Zheng, Peng Sun, and Tinghuai Wang

beta as a therapeutic target in breast cancer stem cells . Journal of the National Cancer Institute 2017 109 1 – 14 . ( https://doi.org10.1093/jnci/djw236 ) 28376210 10 Filardo EJ . Epidermal growth factor receptor (EGFR) transactivation by

Open access

Jiaxin Zhang, Jinlan Jiang, Yao Qin, Yihui Zhang, Yungang Wu, and Huadong Xu

apoptosis of bone mesenchymal stem cells and osteoblasts through oxidative stress, which is related to the pathogenesis of osteoporosis ( 8 , 9 ). The systemic immune-inflammation index (SII) is a new inflammatory index based on peripheral blood neutrophils

Open access

Hui Long, Yanhong Nie, Li Wang, Yong Lu, Yan Wang, Yijun Cai, Zhen Liu, Miaomiao Jia, Qifeng Lyu, Yanping Kuang, and Qiang Sun

nuclear transfer and the embryo stem cell establishment ( 4 , 5 ). These achievements were dependent on an amount of oocytes retrieval in ovarian stimulation. However, ovarian stimulation regimen in nonhuman primates has not been set up as well as human

Open access

Kirsty G Pringle, Sarah J Delforce, Yu Wang, Katie A Ashton, Anthony Proietto, Geoffrey Otton, C Caroline Blackwell, Rodney J Scott, and Eugenie R Lumbers

MF Zhang S , . Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers. Breast Cancer Research 2015 17 112 . ( doi:10.1186/s13058-015-0622-z ) 37

Open access

Devis Pascut, Sofia Tamini, Silvia Bresolin, Pablo Giraudi, Giuseppe Basso, Alessandro Minocci, Claudio Tiribelli, Graziano Grugni, and Alessandro Sartorio

required for human adipogenesis and drives characteristics of brown adipocytes . Stem Cells 2014 32 1578 – 1590 . ( ) 25 Ying W Tseng A Chang RC-A Wang H Lin Y-L Kanameni S Brehm T Morin A Jones B Splawn T , miR

Open access

Anna-Pauliina Iivonen, Johanna Känsäkoski, Atte Karppinen, Leena Kivipelto, Camilla Schalin-Jäntti, Auli Karhu, and Taneli Raivio

24 Gaston-Massuet C Andoniadou CL Signore M Jayakody SA Charolidi N Kyeyune R Vernay B Jacques TS Taketo MM Le Tissier P , et al . Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and

Open access

Sylvia Thiele, Anke Hannemann, Maria Winzer, Ulrike Baschant, Heike Weidner, Matthias Nauck, Rajesh V Thakker, Martin Bornhäuser, Lorenz C Hofbauer, and Martina Rauner

) ratio in osteoblastic cells promotes osteoclastogenesis, inhibition of osteoblast differentiation, reduced matrix production, increased osteoblast and osteocyte apoptosis and increased autophagy further seem to contribute to GIO ( 5 , 6 , 7 , 8