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Hamidreza Mani, Yogini Chudasama, Michelle Hadjiconstantinou, Danielle H Bodicoat, Charlotte Edwardson, Miles J Levy, Laura J Gray, Janette Barnett, Heather Daly, Trevor A Howlett, Kamlesh Khunti, and Melanie J Davies

approval by East Midlands’ Research Ethics Committee 11/EM/0141, Clinical Trials.Gov registration number Nbib1462864). The intervention was a single seven-hour, group-based, face-to-face structured education programme. The study was powered to detect a mean

Open access

Tiemo S Gerber, Arno Schad, Nils Hartmann, Erik Springer, Ulrich Zechner, and Thomas J Musholt

from the patients was retrieved and reviewed using the Turin consensus algorithm, in the course of which necrosis, the number of mitotic cells per ten high-powered fields (mitotic index) and the extrathyroidal and vascular invasion were determined. The

Open access

Emanuelle Nunes-Souza, Mônica Evelise Silveira, Monalisa Castilho Mendes, Seigo Nagashima, Caroline Busatta Vaz de Paula, Guilherme Guilherme Vieira Cavalcante da Silva, Giovanna Silva Barbosa, Julia Belgrowicz Martins, Lúcia de Noronha, Luana Lenzi, José Renato Sales Barbosa, Rayssa Danilow Fachin Donin, Juliana Ferreira de Moura, Gislaine Custódio, Cleber Machado-Souza, Enzo Lalli, and Bonald Cavalcante de Figueiredo

expression for each biomarker was obtained by quantitative analysis (morphometry). Immunopositive areas of each photomicrograph, in square micrometers, were transformed into a percent by high power field value (HPF). We also counted hematoxylin and immune

Open access

Jakob Høgild Langdahl, Anja Lisbeth Frederiksen, John Vissing, Morten Frost, Knud Bonnet Yderstræde, and Per Heden Andersen

varying proportions of m.3243A>G subjects with DM, IGT and NGT. In addition, low statistical power could explain the diverging results. Our study provides additional evidence for insulin resistance in the early stages of the development of mitochondrial

Open access

Boju Pan, Anqi Wang, Junyi Pang, Yuhan Zhang, Ming Cui, Jian Sun, and Zhiyong Liang

inconsistent, ranging from <1 to >10 mitoses/10 high-power fields (HPF). Additionally, the Ki-67 index ranged from 1 to 20% (mean, 8%). In addition, the atypical mitosis, necrosis and nucleolus in the carcinoma samples were variable. Almost all the patients in

Open access

Natércia Neves Marques de Queiroz, Franciane Trindade Cunha de Melo, Fabrício de Souza Resende, Luísa Corrêa Janaú, Norberto Jorge Kzan de Souza Neto, Manuela Nascimento de Lemos, Ana Carolina Lobato Virgolino, Maria Clara Neres Iunes de Oliveira, Angélica Leite de Alcântara, Lorena Vilhena de Moraes, Tiago Franco David, Wanderson Maia da Silva, Scarlatt Souza Reis, Márcia Costa dos Santos, Ana Carolina Contente Braga de Souza, Pedro Paulo Freire Piani, Neyla Arroyo Lara Mourão, Karem Mileo Felício, João Felício Abrahão Neto, and João Soares Felício

a poor prediction power, altogether being capable of determining only 5.4% of 25(OH)D levels. An inclination coefficient of −0.235 was obtained using BMI and vitamin D level as variables in a simple linear regression model according to the formula

Open access

Cecilia Lundin, Agota Malmborg, Julia Slezak, Kristina Gemzell Danielsson, Marie Bixo, Hanna Bengtsdotter, Lena Marions, Ingela Lindh, Elvar Theodorsson, Mats Hammar, and Inger Sundström-Poromaa

. Free androgen index was calculated as (testosterone/SHBG) ×100. Statistics The power analysis was based on data from Graham and colleagues who used a five-point scale for assessment of sexual desire ( 7 ). Assuming that the SD was twice the size

Open access

Fahim Ebrahimi, Sandrine A Urwyler, Philipp Schuetz, Beat Mueller, Luca Bernasconi, Peter Neyer, Marc Y Donath, and Mirjam Christ-Crain

and metabolic syndrome. However, the current trial was not designed and not powered to investigate the effects on glucose metabolism, since most of the included patients did not have impaired glucose tolerance (only 16 (24%) patients were diabetic

Open access

Laura P B Elbers, Marije Wijnberge, Joost C M Meijers, Dennis C W Poland, Dees P M Brandjes, Eric Fliers, and Victor E A Gerdes

assumption of an effect size of 0.5 (calculated as the difference of the means divided by the mean of the standard deviations), with a power of 80% and an alpha error of 0.05. Performing a secondary analysis with all patients with vitamin D deficiency at

Open access

Weiwei He, Bin Wang, Kaida Mu, Jing Zhang, Yanping Yang, Wei Yao, Sheli Li, and Jin-an Zhang

make a sufficient power over 80% required at least 331 cases and 265 controls for rs153109, and at least 799 cases and 640 controls for both rs181206 and rs17855750. The final sample size in our case-control study led to a statistical power of over 95