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Bo Zhu, Yumei Chen, Fang Xu, Xiaolu Shen, Xuanyu Chen, Jieqiang Lv, and Songying Zhang

group had 10–12 mice. The study was approved by the ethics commitment of Assisted Reproduction Unit, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine. Islet isolation and culture The islets were isolated from the female mice as

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Yael Sofer, Nava Nevo, Michal Vechoropoulos, Gabi Shefer, Etty Osher, Nathan Landis, Karen Tordjman, Geoffrey L Hammond, and Naftali Stern

reproduction . Biology of Reproduction 2011 85 431 – 441 . ( ) 21613632 10.1095/biolreprod.111.092593 2 Hammond GL Wu TS Simard M. Evolving utility of sex hormone-binding globulin measurements

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M A Webb, H Mani, S J Robertson, H L Waller, D R Webb, C L Edwardson, D H Bodicoat, T Yates, K Khunti, and M J Davies

Phillips DI Norman RJ Davies MJ. The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria . Human Reproduction 2010 25 544 – 551 . ( ) 2 Carmina E Lobo

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Zeeshan Javed, Maria Papageorgiou, Leigh A Madden, Alan S Rigby, Eric S Kilpatrick, Stephen L Atkin, and Thozhukat Sathyapalan

-Kandarakis E Paterakis T Alexandraki K Piperi C Aessopos A Katsikis I Katsilambros N Kreatsas G Panidis D . Indices of low-grade chronic inflammation in polycystic ovary syndrome and the beneficial effect of metformin . Human Reproduction

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Fiona Broughton Pipkin, Hiten D Mistry, Chandrima Roy, Bernhard Dick, Jason Waugh, Rebecca Chikhi, Lesia O Kurlak, and Markus G Mohaupt

Liggins GC . The role of cortisol in preparing the fetus for birth . Reproduction, Fertility, and Development 1994 6 141 – 150 . ( doi:10.1071/RD9940141 ). 4 Liggins GC . Adrenocortical-related maturational events in the fetus . American

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Giovanni Tulipano

and follicle-stimulating hormone/luteinizing hormone (FSH/LH) from gonadotrophs. The pituitary hormones act on endocrine and non-endocrine target tissues involved in different physiological functions including somatic growth, reproduction, metabolism

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Christian Trummer, Stefan Pilz, Verena Schwetz, Barbara Obermayer-Pietsch, and Elisabeth Lerchbaum

.fertnstert.2004.10.014 8 Thonneau P Marchand S Tallec A Ferial ML Ducot B Lansac J Lopes P Tabaste JM Spira A. Incidence and main causes of infertility in a resident population (1,850,000) of three French regions (1988–1989) . Human Reproduction 1991 6

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Feifei Cheng, Noel Yat Hey Ng, Claudia Ha Ting Tam, Yuying Zhang, Cadmon King Poo Lim, Guozhi Jiang, Alex Chi Wai Ng, Tiffany Tse Ling Yau, Lai Ping Cheung, Aimin Xu, Juliana C N Chan, and Ronald C W Ma

Q Yang D Li S Lu S Wu X Wei Z Song X Wang X Fu S Prevalence of polycystic ovary syndrome in women in China: a large community-based study . Human Reproduction 2013 28 2562 – 2569 . ( ) 3 Cheung

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Sarmistha Banerjee, Allison M Hayes, and Bernard H Shapiro

.1412 ) 8 Goldman AS Animal models of inborn errors of steroidogenesis and steroid action . In Mammalian Reproduction, Colloquium der Gesellschaft für Biologische Chemie , pp. 9 – 1 1 . Eds Gibian H Plotz EJ . Berlin: Springer, 1970 . 9 Feder

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J Brossaud, V Pallet, and J-B Corcuff

Knutson D. Vitamin A in reproduction and development . Nutrients 2011 3 385 – 428 . ( doi:10.3390/nu3040385 ) 22254103 10.3390/nu3040385 36 Angioni AR Lania A Cattaneo A Beck-Peccoz P Spada A. Effects of chronic retinoid