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M A Webb, H Mani, S J Robertson, H L Waller, D R Webb, C L Edwardson, D H Bodicoat, T Yates, K Khunti, and M J Davies

were eligible. Exclusion criteria were pregnancy, diabetes, use of corticosteroids, a disabling physical or mental condition and inability to speak English. The SUCCESS study recruited a total of 161 participants and for the purpose of this study

Open access

Sandra R Dahl, Ingrid Nermoen, Ingeborg Brønstad, Eystein S Husebye, Kristian Løvås, and Per M Thorsby

–MS/MS methods are superior to immunoassays in monitoring patients with 21OHD on corticosteroid replacement therapy as they are more specific and can be multiplexed. Immunoassays seem to overestimate high concentrations of 17OHP and androstenedione considerably

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Marloes L P Langelaan, Jérôme M H Kisters, Mirjam M Oosterwerff, and Arjen-Kars Boer

cortisol concentrations ( 8 , 9 ). LC–MS/MS analyses are not influenced by changes in e.g. concentrations of cortisol-binding globulin or cross-reactivity with other corticosteroid substances. In addition, LC–MS/MS analysis enables the analysis of cortisol

Open access

Hauke Thomsen, Xinjun Li, Kristina Sundquist, Jan Sundquist, Asta Försti, and Kari Hemminki

Introduction Addison’s disease (AD) is an autoimmune disease (AID) characterized by a gradual autoantibody destruction of the adrenal cortex with resulting impaired production of corticosteroids and mineralocorticoids ( 1 ). Most patients

Open access

Karolien Van De Maele, Jean De Schepper, Jesse Vanbesien, Monique Van Helvoirt, Ann De Guchtenaere, and Inge Gies

with corticosteroids, metformin and vitamin D supplementation. The studied outcomes combined anthropometric, densitometric and biochemical measurements. Following anthropometric measures were performed at baseline and at the end: body weight and

Open access

Anna Olsson-Brown, Rosemary Lord, Joseph Sacco, Jonathan Wagg, Mark Coles, and Munir Pirmohamed

reversible with corticosteroid containing immunosuppression, the endocrinopathies appear to be irreversible and, in the majority of cases, require lifelong replacement therapy ( 11 ). Thyroid dysfunction reported within metastatic malignant melanoma

Open access

Carolina Inda, Natalia G Armando, Paula A dos Santos Claro, and Susana Silberstein

controlling energy metabolism ( 12 , 13 ). The adaptive function of the HPA depends on the negative feedback mechanisms that bring the HPA to baseline levels. Corticosteroids are released in a pulsatile ultradian pattern that may vary in amplitude and

Open access

Dimitra Argyro Vassiliadi, Ioannis Ilias, Maria Pratikaki, Edison Jahaj, Alice G Vassiliou, Maria Detsika, Kleio Ampelakiotou, Marina Koulenti, Konstantinos N Manolopoulos, Stamatis Tsipilis, Evdokia Gavrielatou, Aristidis Diamantopoulos, Alexandros Zacharis, Nicolaos Athanasiou, Stylianos Orfanos, Anastasia Kotanidou, Stylianos Tsagarakis, and Ioanna Dimopoulou

patterns. Chen et al . ( 19 ) reported a significant (56%) proportion of subnormal TSH levels, compared to controls, in patients with COVID-19. It should be noted that more than half of these patients were on corticosteroids, known to lower TSH levels ( 27

Open access

Chenjia Tang, Yanting Dong, Lusi Lu, and Nan Zhang

patients with SAT. The risk of recurrence in patients with SAT was HLA-dependent, and the co-presence of HLA-B*18:01 and –B*35 was a determining factor ( 16 ). Some studies have shown that patients who received corticosteroid therapy tended to receive T4

Open access

Ida Staby, Jesper Krogh, Marianne Klose, Jonas Baekdal, Ulla Feldt-Rasmussen, Lars Poulsgaard, Jacob Bertram Springborg, and Mikkel Andreassen

JOL Dekkers OM . Adrenal insufficiency in corticosteroids use: systematic review and meta-analysis . Journal of Clinical Endocrinology and Metabolism 2015 100 2171 – 2180 . ( ) 23 Joseph RM Hunter AL