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Bliss Anderson and Daniel L Morganstein

–8% (49) (with anti-PD-1) Seen less commonly in anti-CTLA-4 therapy (8, 9) Anti-thyroid drugs only in Graves’ disease (51, 52, 53, 54, 55) 14–20% (combined therapy) (49, 50) High dose steroids if severe thyroiditis seen (49

Open access

Wiebke Arlt and the Society for Endocrinology Clinical Committee

that their kit is up to date Provide the patient with a Steroid Emergency Card and encourage them to wear medical alert bracelets, in addition to keeping the steroid emergency card with them at all times and

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Peter Ergang, Anna Mikulecká, Martin Vodicˇka, Karla Vagnerová, Ivan Mikšík, and Jirˇí Pácha

biologically inactive 11-oxo steroids (cortisone and 11-dehydrocorticosterone) to cortisol and corticosterone, amplifying the cellular glucocorticoid action ( 5 ). 11HSD1 is expressed in many organs and tissues, including lymphoid organs and immune cells ( 6

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André Marques-Pinto and Davide Carvalho

) and ethinyl oestradiol (EE) (20) , as well as non-steroidal anti-inflammatory drugs (NSAID) and acetaminophen (21) . Natural chemicals such as genistein, a phytoestrogen (22) and heavy metals (23) can also have endocrine-disruptive effects

Open access

M P Schuijt, C G J Sweep, R van der Steen, A J Olthaar, N M M L Stikkelbroeck, H A Ross, and A E van Herwaarden

continuous infusion of the labeled steroid in a dialysate matrix. The abundance was compared between a dialysate matrix and mobile phase at the retention time of testosterone. Total imprecision was assessed by an adapted CLSI EP5 protocol with pooled

Open access

Shuang Ye, Yuanyuan Xu, Jiehao Li, Shuhui Zheng, Peng Sun, and Tinghuai Wang

, more evidence demonstrates estrogen could influence cell proliferation and migration elicited by combining steroid hormone receptors such as G protein-coupled estrogen receptor 1 (GPER), ERβ or estrogen-related receptors ( 7 , 8 , 9 , 10 ). GPER

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Helga Schultz, Svend Aage Engelholm, Eva Harder, Ulrik Pedersen-Bjergaard, and Peter Lommer Kristensen

Diamant M. Steroid diabetes: from mechanism to treatment? Netherlands Journal of Medicine 2014 72 62 – 72 . 2 Ellis ME Weiss RB Korzun AH Rice MA Norton L Perloff M Lesnick GJ Wood WC . Hyperglycemic complications associated

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Alessandra Gambineri and Carla Pelusi

tissues, particularly on adipose tissue. The sexual dimorphism of androgens in the pathophysiology of T2DM is emphasized. Sex hormone differences between the sexes Males and females produce the same steroid hormones in a similar way. Regarding

Open access

Masafumi Tetsuka and Misato Tanakadate

cortisone ([1,2- 3 H]-cortisone 60 Ci/mmol; American Radiolabeled Chemicals Inc., Tokyo, Japan). After culturing, the medium was recovered and the steroids were extracted once with 1 mL diethyl ether for 5 min. The organic phase was removed and evaporated at

Open access

Shenglong Le, Leiting Xu, Moritz Schumann, Na Wu, Timo Törmäkangas, Markku Alén, Sulin Cheng, and Petri Wiklund

Introduction Sex steroids are important regulators of pubertal development and their biological action is governed by sex hormone-binding globulin (SHBG) ( 1 ). Serum SHBG levels rise from birth to early childhood, then decline in early