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Xiuzhen Zhang, Dan Xu, Ping Xu, Shufen Yang, Qingmei Zhang, Yan Wu, and Fengyi Yuan

glycemic control ( 7 , 16 , 18 , 22 , 23 ). Conversely, new evidence has revealed modest improvements in the HbA1c level of T1DM patients with adjuvant metformin therapy. One meta-analysis highlighted that metformin reduced the HbA1c level by 0.26% in T

Open access

Malin Nylander, Signe Frøssing, Caroline Kistorp, Jens Faber, and Sven O Skouby

endothelial dysfunction, which is associated with an increased risk of cardiovascular disease (CVD) ( 4 ). PCOS is associated with both CVD and venous thromboembolism (VTE). A recent meta-analysis found an odds ratio of 1.44 (1.13–1.84) for coronary heart

Open access

Iulia Soare, Anca Sirbu, Mihai Mircea Diculescu, Bogdan Radu Mateescu, Cristian Tieranu, Sorina Martin, Carmen Gabriela Barbu, Mirela Ionescu, and Simona Fica

osteopenia ranges from 32 to 36% and osteoporosis from 7 to 15% ( 2 ). Fracture risk is higher in these patients than in healthy subjects, according to a recent meta-analysis showing a 32% increased risk, which is consistent with different cohort studies

Open access

Małgorzata Kałużna, Agnieszka Nomejko, Aleksandra Słowińska, Katarzyna Wachowiak-Ochmańska, Katarzyna Pikosz, Katarzyna Ziemnicka, and Marek Ruchała

) can be associated with lower SS ( 12 ). However, Silva et al. found that 81.3% of PCOS women were satisfied with their sexual life ( 13 ). Moreover, Zhao et al. ’s meta-analysis suggested no direct association between PCOS and the risk of female

Open access

Keiko Ohkuwa, Kiminori Sugino, Mitsuji Nagahama, Wataru Kitagawa, Kenichi Matsuzu, Akifumi Suzuki, Chisato Tomoda, Kiyomi Hames, Junko Akaishi, Chie Masaki, and Koichi Ito

meta-analysis of 3081 patients, Feng et al. reported that pretreatment NLR may be an excellent biomarker for predicting tumor size, metastasis, and prognosis in thyroid cancer ( 32 ). In this study, NLR levels at the time of initial RAI treatment were

Open access

B C M Hermans, J L Derks, H J M Groen, J A Stigt, R J van Suylen, L M Hillen, E C van den Broek, E J M Speel, and A-M C Dingemans

2016 . 22 Li D Zhu X Wang H Qiu M Li N . Should aggressive thoracic therapy be performed in patients with synchronous oligometastatic non-small cell lung cancer? A meta-analysis . Journal of Thoracic Disease 2017 310 – 317 . ( https

Open access

N K Stepto, D Hiam, M Gibson-Helm, S Cassar, C L Harrison, S K Hutchison, A E Joham, B J Canny, A Moreno-Asso, B J Strauss, N Hatzirodos, R J Rodgers, and H J Teede

. References 1 Bozdag G Mumusoglu S Zengin D Karabulut E Yildiz BO . The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis . Human Reproduction 2016 31 2841 – 2855 . (

Open access

Marra Jai Aghajani, Tao Yang, Ulf Schmitz, Alexander James, Charles Eugenio McCafferty, Paul de Souza, Navin Niles, and Tara L Roberts

-1, has been shown to induce potent inhibition of T-cell mediated anti-tumoural immunity ( 10 ). Elevated PD‐L1 levels have been associated with a poor prognosis in multiple cancer types ( 11 ). We have completed a meta-analysis confirming that non

Open access

R Perchard, L Magee, A Whatmore, F Ivison, P Murray, A Stevens, M Z Mughal, S Ehtisham, J Campbell, S Ainsworth, M Marshall, M Bone, I Doughty, and P E Clayton

seasonality was eliminated with a vitamin D-fortified diet ( 16 ). In a systematic review and meta-analysis conducted by Zipitis and coworkers ( 17 ), the risk of T1D was significantly reduced in individuals who had received cholecalciferol in early infancy

Open access

Xia Wu, Zhiling Li, Wenjiang Sun, and Huan Zheng

widely used in East Asian countries over the past 2 decades ( 28 ). A meta-analysis of cohort studies conducted in the general population, with hypertension, diabetes, end-stage renal disease, and other high-risk individuals, showed that a 1 m/s increase