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K Amrein, A Papinutti, E Mathew, G Vila, and D Parekh

Hypercalcemia may occur, but less frequent compared with ‘older’ active analogs Very expensive What endocrinology can learn from intensive care and vice versa Sample size and power of a study So far, many single vitamin D intervention

Open access

Dorte Glintborg, Magda Lambaa Altinok, Pernille Ravn, Kurt Bjerregaard Stage, Kurt Højlund, and Marianne Andersen

weeks prior to evaluation. Power calculation The primary endpoint of the study was change in adrenal activity (evaluated by 60 min area under the curve (AUC) for ACTH-stimulated cortisol levels) during treatment with escitalopram/placebo. The

Open access

T Grimmichova, M Haluzik, K Vondra, P Matucha, and M Hill

iodine sufficiency ( 15 ). The power of the sample size was established. The patients were recruited from October 2013 to February 2018. Patient history, ultrasound of neck (US), and biochemical testing were done at the Institute of Endocrinology and 2nd

Open access

Vito Francic, Martin Keppel, Verena Schwetz, Christian Trummer, Marlene Pandis, Valentin Borzan, Martin R Grübler, Nicolas D Verheyen, Marcus E Kleber, Graciela Delgado, Angela P Moissl, Benjamin Dieplinger, Winfried März, Andreas Tomaschitz, Stefan Pilz, and Barbara Obermayer-Pietsch

size of 0.5, for a two-sided alternative hypothesis with an α of 0.05 and a power of 90%. Further details can be found in the publication of the original study ( 23 ). Recruitment took place from June 2011 to August 2014 and 200 Caucasian study

Open access

Marta Fichna, Piotr P Małecki, Magdalena Żurawek, Katarzyna Furman, Bolesław Gębarski, Piotr Fichna, and Marek Ruchała

-squaretest was used for association analyses on 2 × 2 and 2 × 3 contingency tables. Two-tailed P values <0.05 were considered statistically significant. The power of the study was evaluated by means of the online PS power and sample size calculator v.2

Open access

Benjamin D Maylor, Julia K Zakrzewski-Fruer, Charlie J Orton, and Daniel P Bailey

any allergies to the food and drink being provided in the study. Sample size Sample size estimations were based on previous data ( 18 ). Based on a 10% within-group error variance, a within-person correlation of 0.6, 80% power, and α = 0.05, it

Open access

Angelica Lindén Hirschberg

IGF ( 43 ), all of which may enhance skeletal muscular activity. Obviously, muscle growth and the accompanying increase in strength and power could enhance performance. In addition, bone formation is stimulated by androgens, both directly and in part

Open access

Yun Cai, Jieni Yan, Yong Gu, Heng Chen, Yang Chen, Xinyu Xu, Mei Zhang, Liping Yu, Xuqin Zheng, and Tao Yang

differences of the TPOAb-positive proportion as well as the H-TPOAb proportion between IA-2A-negative and -positive patients (both P < 0.05) further indicate the relations between IA-2A and TPOAb titers. Our study is powered by a large number of GD, HT, T1

Open access

Selma Flora Nordqvist, Victor Brun Boesen, Åse Krogh Rasmussen, Ulla Feldt-Rasmussen, Laszlo Hegedüs, Steen Joop Bonnema, Per Karkov Cramon, Torquil Watt, Mogens Groenvold, and Jakob Bue Bjorner

values may be used in classical power and sample size calculation for future clinical trials, comparing mean levels of groups. In some instances (e.g. important outcomes for non-toxic goiter interventions), smaller differences may be argued for ( 35

Open access

Xingrong Tan, Wenjing Hu, Shan Yang, Han Dai, Shangcheng Xu, Gangyi Yang, Ling Li, Shiguo Tang, and Yi Wang

occurrence of MetS and its components was predicted by binary logistic regression analysis with cytokine concentration as the independent variable. A P -value <0.05 (two-tailed) was considered to be significant. G*Power can be used to compute effect sizes