Introduction Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy, accounting for 88% of thyroid carcinomas ( 1 , 2 ). Prognosis remains excellent and treatment, typically involving surgery followed by radioactive iodine
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Lauren E Henke, John D Pfeifer, Thomas J Baranski, Todd DeWees, and Perry W Grigsby
Jiwen Yang, Yayin Huang, Bohan Dong, and Yunhai Dai
in vitro . Introduction Thyroid cancer is a common endocrine malignant cancer ( 1 ). The survival of patients with thyroid cancer has improved with the combined therapy of surgery and radioactive iodine (RAI) therapy. However, the
Changjiao Yan, Meiling Huang, Xin Li, Ting Wang, and Rui Ling
. Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial . Lancet 2014 384 . ( https://doi.org/10.1016/S0140-6736(14)60421-9 ) 24768112
Wei Sun, Boyuan Zheng, Zhihong Wang, Wenwu Dong, Yuan Qin, and Hao Zhang
studies have reported benefits of PCLND in patients with cN0. For example, PCLDN can help to accurately diagnose tumor-node-metastasis (TNM) staging, help decide on the use of thyroid-stimulating hormone (TSH) suppression therapy or radioactive iodine (RAI
Katerina Saltiki, Elli Anagnostou, George Simeakis, Sofia Kouki, Anastasia Angelopoulou, Leda Sarika, Alexandra Papathoma, and Maria Alevizaki
metastases from PTC were present in 2/9 patients (the tall cell variant and one classical PTC). Three out of 9 patients received Radioactive Iodine therapy. All patients are in remission concerning PTC. Of the non-exon 8 carriers, only 1/48 (2.1%) had
Wei Li, Qing Huang, Danyang Sun, Guizhi Zhang, and Jian Tan
) ( 1 ). Through surgery and radioactive iodine ablation, most PTC patients have a good prognosis; however, a significant proportion of patients have persistent or recurrent disease and suffer from frequent recurrences or even distant metastases, leading
Bilal B Mughal, Jean-Baptiste Fini, and Barbara A Demeneix
chlorine and bromine. Interestingly, THs are the only complex halogenated (iodine) molecules produced by and necessary for vertebrate homeostasis, making TH physiology highly vulnerable to EDCs. Halogen-substituted phenolic moieties can mimic natural THs
