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Sebastião Freitas de Medeiros, Márcia Marly Winck Yamamoto, Matheus Antônio Souto de Medeiros, Bruna Barcelo Barbosa, José Maria Soares Junior, and Edmund Chada Baracat

-analysis . Human Reproduction Update 2018 694 – 709 . ( ) 2 Lauritsen MP Bentzen JG Pinborg A Loft A Forman JL Thuesen LL Cohen A Hougaard DM Nyboe Andersen A . The prevalence of polycystic ovary

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Kristian Almstrup, Hanne Frederiksen, Anna-Maria Andersson, and Anders Juul

Research and Research Training in Endocrine Disrupting Effects of Male Reproduction and Child Health (EDMaRC). Author contribution statement K A and A J designed and conceptualized the study. K A and H F conducted the experiments and gathered the

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Xia Wu, Zhiling Li, Wenjiang Sun, and Huan Zheng

criteria and long-term health risks related to polycystic ovary syndrome (PCOS) . Human Reproduction 2004 19 41 – 47 . ( ) 21 Hulley SB Designing Clinical Research . Lippincott Williams & Wilkins, 2013

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Xiying Zeng, Yinxiang Huang, Mulin Zhang, Yun Chen, Jiawen Ye, Yan Han, Danyan Ma, Xin Zheng, Xiaohong Yan, and Changqin Liu

serum anti-Mullerian-hormone levels in severely obese women . Journal of Assisted Reproduction and Genetics 2018 35 1317 – 1324 . ( ) 10 Cassar S Teede HJ Moran LJ Joham AE Harrison CL Strauss BJ

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Xingyan Liu, Mei Xu, Min Qian, and Lindong Yang

Reproduction 2012 18 320 – 324 . ( ) 14 Carey AH Waterworth D Patel K White D Little J Novelli P Franks S Williamson R . Polycystic ovaries and premature male pattern baldness are associated with one

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Malin Nylander, Signe Frøssing, Caroline Kistorp, Jens Faber, and Sven O Skouby

guidance. References 1 Bozdag G Mumusoglu S Zengin D Karabulut E Yildiz BO. The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis . Human Reproduction 2016 31 2841

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Catarina I Gonçalves, José M Aragüés, Margarida Bastos, Luísa Barros, Nuno Vicente, Davide Carvalho, and Manuel C Lemos

inborn errors of metabolism ( 21 ). The involvement of digenism as a cause of CHH suggests that there are multiple layers of redundancy in the hypothalamic–pituitary–gonadal (HPG) control of reproduction and that, at least in the case of less severe

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Stavroula A Paschou, Eleni Palioura, Dimitrios Ioannidis, Panagiotis Anagnostis, Argyro Panagiotakou, Vasiliki Loi, Georgios Karageorgos, Dimitrios G Goulis, and Andromachi Vryonidou

according to the Rotterdam consensus criteria . Human Reproduction 2009 24 710 – 717 . ( doi:10.1093/humrep/den433 ) 6 Castelo-Branco C Steinvarcel F Osorio A Ros C Balasch J. Atherogenic metabolic profile in PCOS patients: role

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Annette Mouritsen, Alexander Siegfried Busch, Lise Aksglaede, Ewa Rajpert-De Meyts, and Anders Juul

Education and Science (DFF-1331-00113); The Innovation Fund Denmark (InnovationsFonden, 14-2013-4); The International Center for Research and Research Training in Endocrine Disrupting Effects of Male Reproduction and Child Health (EDMaRC). References

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Yao Ye, Aurelia Vattai, Nina Ditsch, Christina Kuhn, Martina Rahmeh, Sven Mahner, Myriam Ripphahn, Roland Immler, Markus Sperandio, Udo Jeschke, and Viktoria von Schönfeldt

RW Critchley HO. Chemokine and cyclooxygenase-2 expression in human endometrium coincides with leukocyte accumulation . Human Reproduction 1997 12 1300 – 1306 . ( ) 10.1093/humrep/12.6.1300 16 Toth B