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Sandeep Kumar Parvathareddy, Abdul K Siraj, Zeeshan Qadri, Saeeda O Ahmed, Felisa DeVera, Saif Al-Sobhi, Fouad Al-Dayel, and Khawla S Al-Kuraya

ethnicity. In addition, using N stage classification only might underestimate the significance and the extent of the burden of the disease since it is based solely on anatomical location of LN metastasis. An additional emerging prognostic factor in PTC is

Open access

Kjell Oberg, Eric Krenning, Anders Sundin, Lisa Bodei, Mark Kidd, Margot Tesselaar, Valentina Ambrosini, Richard P Baum, Matthew Kulke, Marianne Pavel, Jaroslaw Cwikla, Ignat Drozdov, Massimo Falconi, Nicola Fazio, Andrea Frilling, Robert Jensen, Klaus Koopmans, Tiny Korse, Dik Kwekkeboom, Helmut Maecke, Giovanni Paganelli, Ramon Salazar, Stefano Severi, Jonathan Strosberg, Vikas Prasad, Aldo Scarpa, Ashley Grossman, Annemeik Walenkamp, Mauro Cives, Irene Virgolini, Andreas Kjaer, and Irvin M Modlin

Leary C Mares JE Abdalla EK Fleming JB Vauthey JN Rashid A One hundred years after ‘carcinoid’: epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the united states . Journal of Clinical Oncology

Open access

Marra Jai Aghajani, Tara Laurine Roberts, Tao Yang, Charles Eugenio McCafferty, Nicole J Caixeiro, Paul DeSouza, and Navin Niles

reduce patient exposure to avoidable toxicities, and the financial burden of these therapies on healthcare systems. Elevated sPD-L1 has recently been identified as a poor prognostic factor in several cancer types, including multiple myeloma, diffuse

Open access

Guoquan Zhu, Yuying Deng, Liqin Pan, Wei Ouyang, Huijuan Feng, Juqing Wu, Pan Chen, Jing Wang, Yanying Chen, and Jiaxin Luo

-mutated allele was not preferentially associated with poor prognostic factors, based on the observation of 132 cases of well-differentiated PTC with follow-up periods ranging from 13–372 months. Thus, they suggest reevaluating the role of the BRAF V600E

Open access

Klaus W Fagerstedt, Tom Böhling, Harri Sihto, Tarja Salonen, Fang Zhao, Mia Kero, Leif C Andersson, and Johanna Arola

from hypoxia and oxidative stress ( 12 ). Expression of STC1 has been shown to be a negative prognostic factor for gastric cancer ( 13 ). The role of STC1 in NE tumors is unknown. Other recently reported markers for neuroendocrine tumors include

Open access

Olof Joakim Pettersson, Katarzyna Fröss-Baron, Joakim Crona, and Anders Sundin

considerably during treatment. We also propose that TGR between baseline and 10-months follow-up should be further evaluated as a prognostic factor and that these findings should be investigated prospectively in a larger study. This also warrants future

Open access

Matteo Scopel, Eugenio De Carlo, Francesca Bergamo, Sabina Murgioni, Riccardo Carandina, Anna Rita Cervino, Marta Burei, Federica Vianello, Vittorina Zagonel, Matteo Fassan, and Roberto Vettor

pancreas, followed at a distance by the lung and rectum ( 6 ). Bone metastases can have an important impact on the patient’s quality of life and are considered negative prognostic factors of NETs ( 7 , 8 ). The sites most frequently affected are the

Open access

Alexander Heinzel, Dirk Müller, Hanneke M van Santen, Sarah C Clement, Arthur B Schneider, and Frederik A Verburg

other prognostic factors as up to and including the seventh version of the TNM system ( 17 ) the presence of distant metastases is the only prognostic factor relevant to DTC-related mortality in patients >18 and <45 years. Although the latest edition of

Open access

Ashley K Clift, Omar Faiz, Robert Goldin, John Martin, Harpreet Wasan, Marc-Olaf Liedke, Erik Schloericke, Anna Malczewska, Guido Rindi, Mark Kidd, Irvin M Modlin, and Andrea Frilling

. Nomograms predicting progression-free survival, overall survival, and pelvic recurrence in locally advanced cervical cancer developed from an analysis of identifiable prognostic factors in patients from nrg oncology/gynecologic oncology group randomized

Open access

Abdul K Siraj, Rong Bu, Maham Arshad, Kaleem Iqbal, Sandeep Kumar Parvathareddy, Tariq Masoodi, Laila Omar Ghazwani, Saif S Al-Sobhi, Fouad Al-Dayel, and Khawla S Al-Kuraya

metastasis and stage IV tumours. We also found low expression of POLE and POLD1 to be associated with poor prognostic factors such as lymph node involvement, grade 3 tumours and stage III tumours in CRC ( 45 ). However, no significant association with disease