women compared to only two of the eleven premenopausal women ( P = 0.08). There was no significant correlation between any other clinical features of HA. Figure 1 Percentage of patients with each symptom. Figure 2 Steroid cell tumor
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Manjeetkaur Sehemby, Prachi Bansal, Vijaya Sarathi, Ashwini Kolhe, Kanchan Kothari, Swati Jadhav-Ramteke, Anurag R Lila, Tushar Bandgar, and Nalini S Shah
Emanuelle Nunes-Souza, Mônica Evelise Silveira, Monalisa Castilho Mendes, Seigo Nagashima, Caroline Busatta Vaz de Paula, Guilherme Guilherme Vieira Cavalcante da Silva, Giovanna Silva Barbosa, Julia Belgrowicz Martins, Lúcia de Noronha, Luana Lenzi, José Renato Sales Barbosa, Rayssa Danilow Fachin Donin, Juliana Ferreira de Moura, Gislaine Custódio, Cleber Machado-Souza, Enzo Lalli, and Bonald Cavalcante de Figueiredo
major steroid products in the fetal zone, namely DHEA and DHEA sulfate (DHEAS), which serve as estrogen precursors essential for the maintenance of pregnancy ( 5 , 6 ). Onset of zonal differential steroidogenic activity and strong remodeling of the
A Daniel Bird, Spencer Greatorex, David Reser, Gareth G Lavery, and Timothy J Cole
the large short-chain dehydrogenase/reductase (SDR) family of enzymes that are NAD + or NADP + dependent oxidoreductases, typically 250–350 amino acids in length ( 3 ). SDR enzymes have a wide range of substrates including steroids, aromatic
Qiuli Liu, Lin-ang Wang, Jian Su, Dali Tong, Weihua Lan, Luofu Wang, Gaolei Liu, Jun Zhang, Victor Wei Zhang, Dianzheng Zhang, Rongrong Chen, Qingyi Zhu, and Jun Jiang
), respectively. Increased levels of ACTH are not only unable to compensate for the deficient cortisol synthesis, but their trophic effects also produce adrenal gland enlargement ( 2 ). Pathologically, CAH is mainly caused by an inborn error of steroid synthesis
Arpna Sharma, Vijay Simha Baddela, Frank Becker, Dirk Dannenberger, Torsten Viergutz, and Jens Vanselow
the test groups with highest fatty acid concentrations. Steroid hormone estimation Concentrations of 17β-estradiol (E2) and progesterone (P4) in the conditioned media were determined by competitive 3H radioimmunoassay (RIA) with rabbit
Shilpa Lingaiah, Laure Morin-Papunen, Terhi Piltonen, Inger Sundström-Poromaa, Elisabet Stener-Victorin, and Juha S Tapanainen
levels). Women using hormonal preparations and medications affecting glucose metabolism and steroid synthesis were excluded from the study. Alternatively, a washout period of 2 months was required for women using hormonal preparations before participating
Annette Mouritsen, Alexander Siegfried Busch, Lise Aksglaede, Ewa Rajpert-De Meyts, and Anders Juul
Estradiol (E2) and dihydrotestosterone (DHT). Finally, T concentration depends on the clearance rate, determined by, conversion of T to its metabolites, conjugation capacity, as well as urinary excretion. The ability of excreting T and other steroids in the
Avinaash Maharaj, Ruth Kwong, Jack Williams, Christopher Smith, Helen Storr, Ruth Krone, Debora Braslavsky, Maria Clemente, Nanik Ram, Indraneel Banerjee, Semra Çetinkaya, Federica Buonocore, Tülay Güran, John C Achermann, Louise Metherell, and Rathi Prasad
which primary adrenal insufficiency (PAI) and steroid-resistant nephrotic syndrome (SRNS) necessitating renal transplantation predominate ( 1 , 2 , 3 , 4 ). Additional clinical features including ichthyosis, progressive neurological disease, primary
Brijesh Krishnappa, Ravikumar Shah, Saba Samad Memon, Chakra Diwaker, Anurag R Lila, Virendra A Patil, Nalini S Shah, and Tushar R Bandgar
(panhypophysitis)) AND ((steroid) OR (glucocorticoid) OR (corticoids) OR (predniso*) OR (corticoster*) OR (methylprednisolone) OR (conservatively) OR (conservative))’ as keywords with ‘humans’ and ‘English’ language filters. We further manually reviewed the
David Mark Robertson, Chel Hee Lee, and Angela Baerwald
). The key ovarian factors believed responsible are the steroids, oestradiol and progesterone, and the protein hormones, inhibin A and B. However, their respective roles are not clearly understood. In a previous study (( 2 ), and ( 3 ) designated in
