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Shan Wu, Jianjun Zhou, Jing Guo, Zhan Hua, Jianchen Li, and Zai Wang

), particularly in liver metastasis ( 10 ). For this reason, sunitinib, a multi-targeted tyrosine kinase receptor inhibitor of VEGFR1-3, platelet-derived growth factor receptor, mast/stem cell growth factor receptor kit, proto-oncogene tyrosine-protein kinase

Open access

Anna Gorbacheva, Anna Eremkina, Daria Goliusova, Julia Krupinova, and Natalia Mokrysheva

targets and develop modern effective therapeutic algorithms for MEN1. However, differentiation of induced pluripotent stem cells, mesenchymal stem cells (MSCs) or fibroblasts into osteoblasts is also a non-trivial task. In particular, stem cells can form

Open access

Jana Ernst, Urszula Grabiec, Kathrin Falk, Faramarz Dehghani, and Kristina Schaedlich

-vitro investigations of our group previously performed in murine C3H10-T1/2 mesenchymal stem cells identifying the induction phase as a particularly vulnerable exposure window of adipogenesis ( 17 , 52 ) and in the SGBS cell model revealing effective but non

Open access

Ping Gu, Yuege Lin, Qi Wan, Dongming Su, and Qun Shu

periodontal stem cells ( 27 ). Importantly, Mohan et al. reported that oxytocin has a proliferative effect on pancreatic β-cells and protects against apoptosis in vitro ( 13 ). β-cell proliferation is important for islet expansion during pregnancy ( 28

Open access

Marra Jai Aghajani, Tao Yang, Ulf Schmitz, Alexander James, Charles Eugenio McCafferty, Paul de Souza, Navin Niles, and Tara L Roberts

-L1 upregulation occurred in parallel with the up- and down-regulation of the stem-cell-related CD44 and CD24 surface markers, respectively; this was also accompanied by a morphological change from tightly arranged epithelial-like cells to widely

Open access

E T Aristizabal Prada and C J Auernhammer

embryonic pathway that is important in juxtacrine signalling between neighbouring cells, regulates cell proliferation and cell differentiation and has been demonstrated to play an essential role in tumourigenesis and maintenance of cancer stem cells (CSCs

Open access

Tatiana V Novoselova, Peter J King, Leonardo Guasti, Louise A Metherell, Adrian J L Clark, and Li F Chan

are known to contain adrenocortical stem/progenitor cells capable of dividing, migrating centripetally and differentiating into mature steroid-producing cell types ( 46 , 47 , 48 ). In keeping with this, the absence of MRAP and therefore ACTH

Open access

Konstantin Yakimchuk, Chandrashekar Bangalore Revanna, Dan Huang, Jose Inzunza, and Sam Okret

. Toxicologic Pathology 2010 38 110 – 122 . ( ) 17 Prins GS Hu WY Shi GB Hu DP Majumdar S Li G Huang K Nelles JL Ho SM Walker CL , et al . Bisphenol A promotes human prostate stem-progenitor cell self

Open access

Alexander V Amram, Stephen Cutie, and Guo N Huang

that thyroid hormones are essential regulators of cardiac regeneration across phylogeny. Thyroid hormones also promote CM differentiation and maturation. They have been widely used to induce maturation of CMs derived from mouse embryonic stem cells

Open access

Huifei Sophia Zheng, Jeffrey G Daniel, Julia M Salamat, Laci Mackay, Chad D Foradori, Robert J Kemppainen, Satyanarayana R Pondugula, Ya-Xiong Tao, and Chen-Che Jeff Huang

were associated with the function and development of neuronal cells. An RNA-seq study showed that the proliferation of cells is the leading functional network in hypothalamic neural-progenitor/stem cells treated with Dex ( 49 ), thereby indicating the