/non-hypertensive group. A study among adults with obesity showed that weight loss decreased interstitial fluid glycerol concentrations during a hyperinsulinemic–euglycemic clamp, suggestive of insulin sensitization, along with decreases in 5α-reductase activity and
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Martijn J J Finken, Aleid J G Wirix, Ines A von Rosenstiel-Jadoul, Bibian van der Voorn, Mai J M Chinapaw, Michaela F Hartmann, Joana E Kist-van Holthe, Stefan A Wudy, and Joost Rotteveel
Rongpeng Gong, Gang Luo, Mingxiang Wang, Lingbo Ma, Shengnan Sun, and Xiaoxing Wei
increased ( 17 ). There are currently a variety of approaches for making a primary diagnosis of IR, either directly or indirectly ( 18 ). The gold standard for diagnosing IR is the hyperinsulinemic-euglycemic clamp test, which was initially developed by
Alessandro Ciresi, Stefano Radellini, Valentina Guarnotta, Maria Grazia Mineo, and Carla Giordano
-016-0475-z 27126309 40 Ciresi A Guarnotta V Pizzolanti G Giordano C . Comparison between euglycemic hyperinsulinemic clamp and surrogate indices of insulin sensitivity in children with growth hormone deficiency . Growth Hormone and IGF Research
Dorte Glintborg, Magda Lambaa Altinok, Pernille Ravn, Kurt Bjerregaard Stage, Kurt Højlund, and Marianne Andersen
urinary cortisol excretion. We used a combination of disease-specific and generic questionnaires to describe HRQoL. Measures of insulin sensitivity were calculated at fasting and by measures derived from 3-h OGTT. The euglycemic–hyperinsulinemic clamp is
Rongpeng Gong, Yuanyuan Liu, Gang Luo, Jiahui Yin, Zuomiao Xiao, and Tianyang Hu
death. Currently, there are several methods for predicting IR directly or indirectly. Among them, the hyperinsulinemic-euglycemic clamp (HEC) test, originally developed by DeFronzo ( 13 ), is considered the gold standard method for diagnosing IR
Christian Trummer, Stefan Pilz, Verena Schwetz, Barbara Obermayer-Pietsch, and Elisabeth Lerchbaum
glucose. In another study by Joham and coworkers ( 48 ), hyperinsulinemic–euglycemic clamps were performed in 42 PCOS patients and 34 control women. In the PCOS group, 25(OH)D concentrations were significantly associated with insulin resistance measured by
Lars Peter Sørensen, Tina Parkner, Esben Søndergaard, Bo Martin Bibby, Holger Jon Møller, and Søren Nielsen
euglycemic hyperinsulinemic clamp technique (26) , which was evident in normal-weight and obese healthy individuals (20, 21, 26) , as well as in individuals with normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and T2DM (24
Tatsuya Kondo, Nobukazu Miyakawa, Sayaka Kitano, Takuro Watanabe, Rieko Goto, Mary Ann Suico, Miki Sato, Yuki Takaki, Masaji Sakaguchi, Motoyuki Igata, Junji Kawashima, Hiroyuki Motoshima, Takeshi Matsumura, Hirofumi Kai, and Eiichi Araki
-Mendia LE Gonzalez-Ortiz M Martinez-Abundis E Ramos-Zavala MG Hernandez-Gonzalez SO Jacques-Camarena O Rodriguez-Moran M The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic
Katrine M Lauritsen, Jens Hohwü Voigt, Steen Bønløkke Pedersen, Troels K Hansen, Niels Møller, Niels Jessen, Lars C Gormsen, and Esben Søndergaard
droplet formation in humans ( 29 ). However, insulin-stimulated glucose uptake in adipose tissue during a hyperinsulinemic-euglycemic clamp has previously been found to be unaffected by 8 weeks of SGLT2 inhibition measured by PET/CT ( 30 ). Therefore
Dmitry M Davydov and Malik K Nurbekov
nongenetic factors, as another study found that overweight women who are homozygous for the D allele of this gene had more intensive glucose utilization (detected by hyperinsulinemic–euglycemic clamps) compared with those who are homozygous for the I
