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Sahar Hossam El Hini, Yehia Zakaria Mahmoud, Ahmed Abdelfadel Saedii, Sayed Shehata Mahmoud, Mohamed Ahmed Amin, Shereen Riad Mahmoud, and Ragaa Abdelshaheed Matta

Introduction Overt hypothyroidism (OH) and subclinical hypothyroidism (SCH) are characterized by the coexistence of traditional cardiovascular disease risk factors, insulin resistance (IR), elevated inflammatory markers, altered hemodynamic

Open access

Ningning Gong, Cuixia Gao, Xuedi Chen, Yu Wang, and Limin Tian

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Anna Olsson-Brown, Rosemary Lord, Joseph Sacco, Jonathan Wagg, Mark Coles, and Munir Pirmohamed

clinical trials included both hyperthyroidism and hypothyroidism (Supplementary Table 1, see section on supplementary materials given at the end of this article) but the clinical and biochemical manifestations were not detailed. Radioisotope scanning of

Open access

Xiaoya Zheng, Heng Xiao, Jian Long, Qiang Wei, Liping Liu, Liping Zan, and Wei Ren

presence of hypothyroidism was defined as a TSH value >5.91 µIU/mL with (overt hypothyroidism) or without (subclinical hypothyroidism) decreased FT3 or FT4 levels. Statistical analysis Statistical analyses were performed using GraphPad Prism 5

Open access

Jaafar Jaafar, Eugenio Fernandez, Heba Alwan, and Jacques Philippe

Common terminology criteria for adverse events V4.0 (CTCAE) for thyroid adverse events. Adverse event Grade 1 2 3 4 5 Hypothyroidism Asymptomatic; clinical or diagnostic observations only; intervention not indicated

Open access

L E Zijlstra, D M van Velzen, S Simsek, S P Mooijaart, M van Buren, D J Stott, I Ford, J W Jukema, and S Trompet

Introduction Subclinical hyperthyroidism has been linked to atrial fibrillation and coronary artery calcification, whereas subclinical hypothyroidism has been associated with hypercholesterolemia and atherosclerosis ( 1 , 2 ). Despite these

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Xingyao Tang, Zhi-Hui Song, Dawei Wang, Jinkui Yang, Marly Augusto Cardoso, Jian-Bo Zhou, and Rafael Simó

factor for dementia, promotes neurocognitive function and regulation metabolic processes ( 4 ). Thyroid dysfunction, including clinical hyperthyroidism, subclinical hyperthyroidism, subclinical hypothyroidism, and clinical hypothyroidism, has been

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Nadia Sawicka-Gutaj, Ariadna Zybek-Kocik, Michał Kloska, Paulina Ziółkowska, Agata Czarnywojtek, Jerzy Sowiński, Dorota Mańkowska-Wierzbicka, and Marek Ruchała

-apoptotic and proinflammatory properties of this adipocytokine has been recently reported ( 11 , 12 , 13 ). In addition, visfatin serum concentrations in hypothyroidism are associated with free thyroid hormones and antithyroperoxidase antibodies, while in

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Caroline Serrano-Nascimento, Rafael Barrera Salgueiro, Kaio Fernando Vitzel, Thiago Pantaleão, Vânia Maria Corrêa da Costa, and Maria Tereza Nunes

). Therefore, several physiological changes occur in the maternal hypothalamus–pituitary–thyroid axis to successfully achieve both maternal and fetal TH serum levels requirements ( 16 ). ID is commonly associated with maternal hypothyroidism and several

Open access

Ruth Percik, Sherwin Criseno, Safwaan Adam, Kate Young, and Daniel L Morganstein

indicated Life-threatening consequences; urgent intervention indicated Death Hypothyroidism Asymptomatic; clinical or diagnostic observations only; intervention not indicated Symptomatic; thyroid replacement indicated; limiting instrumental