1 syndrome in patients. However, the frequency of tumour development and age of onset depended on the background strain and sex of the mice. Thus, overall, more pituitary tumours developed in female C57BL/6 Men1 +/- mice than in female 129S6/SvEv
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Kate E Lines, Mahsa Javid, Anita A C Reed, Gerard V Walls, Mark Stevenson, Michelle Simon, Kreepa G Kooblall, Sian E Piret, Paul T Christie, Paul J Newey, Ann-Marie Mallon, and Rajesh V Thakker
Sayaka Kawano, Yukiko Kawagoe, Kenji Kuwasako, Satoshi Shimamoto, Koji Igarashi, Mariko Tokashiki, Kazuo Kitamura, and Johji Kato
2013, were randomly selected for this study (172 males and 174 females; 62.0±8.9 years, mean± s.d .). Upon visiting the community center of Kiyotake Town, the medical history of the residents, which included the questionnaire of whether or not they have
Lukas Engler, Christian Adolf, Daniel A Heinrich, Anna-Katharine Brem, Anna Riester, Anna Franke, Felix Beuschlein, Martin Reincke, Axel Steiger, and Heike Künzel
Introduction Patients with primary aldosteronism (PA) are thought to be a natural model for chronic aldosterone excess, showing significantly higher scores for depression and anxiety compared to the general population, with females being more
Estelle Bonnet, Mathias Winter, Delphine Mallet, Ingrid Plotton, Claire Bouvattier, Maryse Cartigny, Laetiti Martinerie, Michel Polak, Anne Bachelot, Frédéric Huet, Sabine Baron, Muriel Houang, Sylvie Soskin, Anne Lienhardt, Jérôme Bertherat, Cyril Amouroux, Aurore Bouty, Lise Duranteau, Rémi Besson, Alaa El Ghoneimi, Dinane Samara-Boustani, François Becmeur, Nicolas Kalfa, Françoise Paris, François Medjkane, Aude Brac de la Perrière, Patricia Bretones, Hervé Lejeune, Marc Nicolino, Pierre Mouriquand, Daniela-Brindusa Gorduza, and Claire-Lise Gay
deficiency (HSD17B3). These two rare autosomal recessive conditions display a great heterogeneity at both the genotypic and phenotypic levels ( 1 , 2 , 3 , 4 , 5 , 6 ). Clinical presentations of external genitalia at birth range from a female appearance
Yael Sofer, Nava Nevo, Michal Vechoropoulos, Gabi Shefer, Etty Osher, Nathan Landis, Karen Tordjman, Geoffrey L Hammond, and Naftali Stern
of gestational diabetes as early as 11–13 weeks of gestation ( 15 ). Of note, several studies have shown that the relationship between SHBG levels and diabetes is independent of sex hormones, in both female and male subjects ( 16 , 17 , 18 ). In a
Sarmistha Banerjee, Allison M Hayes, and Bernard H Shapiro
, males and females express different CYP profiles. In some cases, the isoforms may be sex exclusive as is the case of CYP2C12, only expressed in female rats ( 1 , 2 ). More commonly, isoforms are sex predominant: for example, women express greater levels
Luchuan Li, Baoyuan Li, Bin Lv, Weili Liang, Binbin Zhang, Qingdong Zeng, Andrew G Turner, and Lei Sheng
age was 53 ± 13 years with 70.8% ( n = 225) of patients being female. Diagnosis with PHPT was initially based on elevated serum calcium or the presence of parathyroid nodules, primarily evident through regular health check-ups ( n = 130, 41
Henrik Falhammar, Hedi Claahsen-van der Grinten, Nicole Reisch, Jolanta Slowikowska-Hilczer, Anna Nordenström, Robert Roehle, Claire Bouvattier, Baudewijntje P C Kreukels, Birgit Köhler, and on behalf of the dsd-LIFE group
sex hormone levels during adolescence may affect peak bone mass ( 3 ), while high androgen levels may affect voice and insulin sensitivity in females ( 22 ). Thus, more data on the health status in individuals with a DSD are needed, including modifying
Katherine U Gaynor, Irina V Grigorieva, Samantha M Mirczuk, Sian E Piret, Kreepa G Kooblall, Mark Stevenson, Karine Rizzoti, Michael R Bowl, M Andrew Nesbit, Paul T Christie, William D Fraser, Tertius Hough, Michael P Whyte, Robin Lovell-Badge, and Rajesh V Thakker
presence or absence of the X chromosome deletion-insertion in three affected males, four carrier females, and three unaffected related males from the MO kindred ( Fig. 2A ). Thus, individuals II.5, II.6 and III.1, who are unaffected males with
Marie Lindhardt Ljubicic, Trine Holm Johannsen, Margit Bistrup Fischer, Emmie N Upners, Alexander S Busch, Katharina M Main, Anna-Maria Andersson, Casper P Hagen, and Anders Juul
genitalia score (EGS) with scores ranging from 0 (female) to 12 (male) ( 16 ). Hormone assays Serum samples were taken as part of routine follow-up, and all preanalytical handling was identical and carried out the same day as sampling. The serum
