Introduction Subclinical hypothyroidism (SCH), characterized by elevated levels of thyroid-stimulating hormone (TSH) with total thyroxine (TT4) within the normal reference range, is the most common type of thyroid disorder in pregnancy ( 1
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Ling Shan, Yingying Zhou, Shiqiao Peng, Xinyi Wang, Zhongyan Shan, and Weiping Teng
Jeonghoon Ha, Jeongmin Lee, Kwanhoon Jo, Dong-Jun Lim, Moo Il Kang, Bong Yun Cha, and Min-Hee Kim
Introduction Subclinical hypothyroidism (SCH) is defined as a mildly elevated serum thyroid-stimulating hormone (TSH) level with a serum free thyroxine (FT4) level within the normal range ( 1 ). While treatment of SCH is not mandatory in most
Fan Zhang, Jian Chen, Xinyue Lin, Shiqiao Peng, Xiaohui Yu, Zhongyan Shan, and Weiping Teng
Introduction Thyroid hormones (THs) are vital for fetal neurodevelopment. The prevalence of subclinical hypothyroidism (SCH) in the general population is 4–10% and can reach 5% in pregnant women. Haddow et al . investigated the intelligence
Kinnaree Sorapipatcharoen, Thipwimol Tim-Aroon, Pat Mahachoklertwattana, Wasun Chantratita, Nareenart Iemwimangsa, Insee Sensorn, Bhakbhoom Panthan, Poramate Jiaranai, Saisuda Noojarern, Patcharin Khlairit, Sarunyu Pongratanakul, Chittiwat Suprasongsin, Manassawee Korwutthikulrangsri, Chutintorn Sriphrapradang, and Preamrudee Poomthavorn
Introduction Congenital primary hypothyroidism (CH) is classified into thyroid dysgenesis (TD) and thyroid dyshormonogenesis (TDH) ( 1 ). TDH has increasingly been reported while the incidence of TD has remained stable ( 2 , 3 ). Genetic
Nella Augusta Greggio, Elisa Rossi, Silvia Calabria, Alice Meneghin, Joaquin Gutierrez de Rubalcava, Carlo Piccinni, and Antonella Pedrini
Introduction Subclinical hypothyroidism (SH) is a biochemical condition defined as serum thyroid-stimulating hormone (TSH) exceeding the limit of its reference range by age, while the concentration of serum free thyroxin (FT4) remains within
Ulla Schmidt, Birte Nygaard, Ebbe Winther Jensen, Jan Kvetny, Anne Jarløv, and Jens Faber
healthy euthyroid subjects, ∼20% of T 3 is derived from thyroidal secretion and the remaining from local production (2) . By contrast, hypothyroid subjects substituted with levothyroxine ( l -T 4 ) monotherapy demonstrated higher plasma T 4 /T 3 ratio
Chunyun Fu, Shiyu Luo, Yingfeng Li, Qifei Li, Xuehua Hu, Mengting Li, Yue Zhang, Jiasun Su, Xuyun Hu, Yun Chen, Jin Wang, Bobo Xie, Jingsi Luo, Xin Fan, Shaoke Chen, and Yiping Shen
Introduction Congenital hypothyroidism (CH) is one of the most common causes of intellectual disability and growth retardation with worldwide incidence ranging from 1:2000 to 1:4000 newborns ( 1 , 2 , 3 ). Newborn screening allows for early
Sahar Hossam El Hini, Yehia Zakaria Mahmoud, Ahmed Abdelfadel Saedii, Sayed Shehata Mahmoud, Mohamed Ahmed Amin, Shereen Riad Mahmoud, and Ragaa Abdelshaheed Matta
Introduction Overt hypothyroidism (OH) and subclinical hypothyroidism (SCH) are characterized by the coexistence of traditional cardiovascular disease risk factors, insulin resistance (IR), elevated inflammatory markers, altered hemodynamic
Ningning Gong, Cuixia Gao, Xuedi Chen, Yu Wang, and Limin Tian
Anna Olsson-Brown, Rosemary Lord, Joseph Sacco, Jonathan Wagg, Mark Coles, and Munir Pirmohamed
clinical trials included both hyperthyroidism and hypothyroidism (Supplementary Table 1, see section on supplementary materials given at the end of this article) but the clinical and biochemical manifestations were not detailed. Radioisotope scanning of