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Marta Araujo-Castro, Héctor Pian, Ignacio Ruz-Caracuel, Alberto Acitores Cancela, Eider Pascual-Corrales, and Víctor Rodríguez Berrocal

Introduction Acromegaly is a rare disease characterized by the overproduction of growth hormone (GH), which is commonly secreted by a pituitary adenoma (PA). Because of cardiovascular, respiratory, and metabolic comorbidities, patients with

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Nadia Sabbah, Peter Wolf, Céline Piedvache, Séverine Trabado, Tristan Verdelet, Catherine Cornu, Jean-Claude Souberbielle, and Philippe Chanson

Introduction IGF-1 measurement is important for the diagnosis and management of patients with growth hormone (GH) deficiency or acromegaly as well as in their follow-up ( 1 , 2 ). We previously established normative data for six IGF-I assays

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Paula Bruna Araujo, Leandro Kasuki, Carlos Henrique de Azeredo Lima, Liana Ogino, Aline H S Camacho, Leila Chimelli, Márta Korbonits, and Monica R Gadelha

hydrocarbon receptor-interacting protein ( AIP ) gene mutations ( AIPmut ) were first described by Vierimaa and coworkers in 2006 ( 3 ). This study has found AIPmut in seemingly sporadic acromegaly patients and in familial isolated pituitary adenomas (FIPA

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Nidan Qiao

pituitary neoplasms, acromegaly, Cushing’s disease, craniopharyngioma and growth hormone deficiency. More than half of the studies were published in the recent 2 years. Table 2 Summary of studies on sellar region disease using machine learning methods

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Amir H Zamanipoor Najafabadi, Merel van der Meulen, Ana Luisa Priego Zurita, S Faisal Ahmed, Wouter R van Furth, Evangelia Charmandari, Olaf Hiort, Alberto M Pereira, Mehul Dattani, Diana Vitali, Johan P de Graaf, and Nienke R Biermasz

. Pituitary adenomas comprise non-hormone-producing adenomas and adenomas producing an excess of growth hormone (acromegaly), adrenocorticotropic hormone (Cushing’s disease), prolactin (prolactinoma), thyrotropin hormone (TSH-producing adenoma), and

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Kunal Thakkar, Swati Ramteke-Jadhav, Rajeev Kasaliwal, Saba Samad Memon, Virendra Patil, Puja Thadani, Nilesh Lomte, Shilpa Sankhe, Atul Goel, Sridhar Epari, Naina Goel, Anurag Lila, Nalini S Shah, and Tushar Bandgar

hyperprolactinemia. Another patient (case 7) had headache, amenorrhoea, and clinical features of acromegaly. On hormonal evaluation, she had high IGF1 levels and mild hyperprolactinemia ( Table 1 ). In a recent extensive review including 69 patients with GCTs

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Shota Dzemaili, Jitske Tiemensma, Richard Quinton, Nelly Pitteloud, Diane Morin, and Andrew A Dwyer

normative scores for the IPQ-R for the general population (i.e. healthy adults), comparisons were made to patients with acute or chronic pain ( 24 ), men with CHH ( 22 ) and patients with acromegaly ( 24 ) to provide a clinical context for these data. Age at

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L M Mongioì, R A Condorelli, S La Vignera, and A E Calogero

life, HRQoL): GH deficiency (Assessment of Growth Hormone Deficiency in Adults, AGHDA) ( 18 ), acromegaly (Acromegaly Quality of Life questionnaire, AcroQoL) and Cushing’s syndrome (Cushing Quality of Life questionnaire, CushingQoL) ( 19 ). Along the

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Mikkel Andreassen, Anders Juul, Ulla Feldt-Rasmussen, and Niels Jørgensen

Patients characteristics. Numbers Primary diagnosis  Acromegaly 8  Prolactinoma 3  Mixed GH and prolactin secreting adenoma 2  Empty sella 2  Non-secreting adenoma 2

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Peter Wolf, Yvonne Winhofer, Martin Krššák, and Michael Krebs

Metabolic disturbances in patients suffering from excessive production of growth hormone (GH), termed acromegaly, seem to be similar to those in the insulin resistant state, i.e. hyperglycemia, hyperinsulinemia and hypertriglyceridemia ( 63 ). Conversely