vertebrate phyla including human ( 12 , 13 ) and identified as the cognate ligand of the human orphan G protein-coupled receptor, GPR103 ( 10 , 11 , 12 , 14 ). Neuroanatomical observations have revealed that 26RFa- and GPR103-expressing neurons are
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Gaëtan Prévost, Marie Picot, Marie-Anne Le Solliec, Arnaud Arabo, Hind Berrahmoune, Mouna El Mehdi, Saloua Cherifi, Alexandre Benani, Emmanuelle Nédélec, Françoise Gobet, Valéry Brunel, Jérôme Leprince, Hervé Lefebvre, Youssef Anouar, and Nicolas Chartrel
Solène Castellnou, Alexandre Vasiljevic, Véronique Lapras, Véronique Raverot, Eudeline Alix, Françoise Borson-Chazot, Emmanuel Jouanneau, Gérald Raverot, and Hélène Lasolle
Bruns C Weckbecker G de Herder WW , et al . The multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5 . European Journal of Endocrinology 2005 152 645
Hélène Lasolle, Amandine Ferriere, Alexandre Vasiljevic, Sandrine Eimer, Marie-Laure Nunes, and Antoine Tabarin
acromegaly using current criteria of biochemical ‘cure’ . European Journal of Endocrinology 2005 379 – 387 . ( https://doi.org/10.1530/eje.1.01863 ) 3 Gadelha MR Wildemberg LE Bronstein MD Gatto F Ferone D . Somatostatin receptor ligands in
Kjell Oberg, Eric Krenning, Anders Sundin, Lisa Bodei, Mark Kidd, Margot Tesselaar, Valentina Ambrosini, Richard P Baum, Matthew Kulke, Marianne Pavel, Jaroslaw Cwikla, Ignat Drozdov, Massimo Falconi, Nicola Fazio, Andrea Frilling, Robert Jensen, Klaus Koopmans, Tiny Korse, Dik Kwekkeboom, Helmut Maecke, Giovanni Paganelli, Ramon Salazar, Stefano Severi, Jonathan Strosberg, Vikas Prasad, Aldo Scarpa, Ashley Grossman, Annemeik Walenkamp, Mauro Cives, Irene Virgolini, Andreas Kjaer, and Irvin M Modlin
-radioactive without bound isotopes) should be discontinued before somatostatin receptor imaging (SRI). Overall, the heterogeneity in SSR expression was considered a potential sensitivity limitation to this approach because current ligands are SSR2/5 avid. Similarly
Katherine Van Loon, Li Zhang, Jennifer Keiser, Cendy Carrasco, Katherine Glass, Maria-Teresa Ramirez, Sarah Bobiak, Eric K Nakakura, Alan P Venook, Manisha H Shah, and Emily K Bergsland
radiological and nuclear imaging and may be easily missed by conventional radiography. Additional data regarding the sensitivity of other imaging modalities, including gallium-68-labeled somatostatin receptor analogs and sodium fluoride PET, for the detection
T L C Wolters, C D C C van der Heijden, N van Leeuwen, B T P Hijmans-Kersten, M G Netea, J W A Smit, D H J Thijssen, A R M M Hermus, N P Riksen, and R T Netea-Maier
, biochemical, radiological, vascular, cardiac, and sleep parameters in an unselected cohort of patients with acromegaly undergoing presurgical somatostatin receptor ligand therapy . Journal of Clinical Endocrinology and Metabolism 2013 1040 – 1050
Lin Ji, Huan-Tong Wu, Xiao-Yan Qin, and Rongfeng Lan
-CPE may be the opposite regulators of Wnt signaling. Moreover, full-length CPE was found to interact with Wnt3a ligand and the frizzled receptor to form a complex, thereby leading to the disruption of disheveled-induced signalosomes, which play a critical
Rimesh Pal, Sanjay Kumar Bhadada, Awesh Singhare, Anil Bhansali, Sadishkumar Kamalanathan, Manoj Chadha, Phulrenu Chauhan, Ashwani Sood, Vandana Dhiman, Dinesh Chandra Sharma, Uma Nahar Saikia, Debajyoti Chatterjee, and Vikas Agashe
secretion by the tumor tissue. As firm evidence to our hypothesis is the fact that octreotide, a somatostatin receptor ligand, is largely ineffective in correcting the biochemical abnormalities in TIO ( 43 , 44 , 45 ). All the resected tumors ( n = 22
Marko Stojanovic, Zida Wu, Craig E Stiles, Dragana Miljic, Ivan Soldatovic, Sandra Pekic, Mirjana Doknic, Milan Petakov, Vera Popovic, Christian Strasburger, and Márta Korbonits
://doi.org/10.1074/jbc.272.14.8878 ) 10.1074/jbc.272.14.8878 12 Carver LA Bradfield CA . Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo . Journal of Biological Chemistry 1997 272 11452 – 11456
Esben Thyssen Vestergaard, Morten B Krag, Morten M Poulsen, Steen B Pedersen, Niels Moller, Jens Otto Lunde Jorgensen, and Niels Jessen
Introduction GH release from the pituitary gland is considered to be regulated at the hypothalamic level by GH releasing hormone (GHRH) and somatostatin (1) . More recently, ghrelin, an endogenous ligand of the GH secretagogue receptor (GHS-R), has
