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Elin Kahlert, Martina Blaschke, Knut Brockmann, Clemens Freiberg, Onno E Janssen, Nikolaus Stahnke, Domenika Strik, Martin Merkel, Alexander Mann, Klaus-Peter Liesenkötter, and Heide Siggelkow

-GT (>40 U/I) (mean ±  s.d. , n  = 213). Treatment with hGH was documented for 130 women (50%). Therapy was started at an average age of 9.8 ± 3.4 years and continued for 6.1 ± 3.0 years. We discovered that the start of hGHT correlated

Open access

M Krause, H Frederiksen, K Sundberg, F S Jørgensen, L N Jensen, P Nørgaard, C Jørgensen, P Ertberg, J H Petersen, U Feldt-Rasmussen, A Juul, K T Drzewiecki, N E Skakkebaek, and A M Andersson

associations of the exposure biomarkers to IGF-I were directly associated or possibly mediated through IGFBP3. Calculations of mediation proportions were performed in the lava-package (version 1.5.1 ( 33 )) in the statistical software ‘R’ (version 3.3.2 ( 34

Open access

Werner F Blum, Abdullah Alherbish, Afaf Alsagheir, Ahmed El Awwa, Walid Kaplan, Ekaterina Koledova, and Martin O Savage

since 1985, when the global Creutzfeldt–Jakob epidemic, related to the use of pituitary-derived hGH, precipitated its licensing by the US Food and Drug Administration and European Medicines Agency. However, rhGH therapy has evolved in the past 30 years

Open access

Charlotte Höybye, Andreas F H Pfeiffer, Diego Ferone, Jens Sandahl Christiansen, David Gilfoyle, Eva Dam Christoffersen, Eva Mortensen, Jonathan A Leff, and Michael Beckert

results of a phase II, randomized, active controlled, open label study of safety and efficacy of HM10560A a long acting r-Hgh-HMbib1 conjugate in adult patients with growth hormone deficiency (AGHD) . In ENDO 2015 meeting abstracts . Presented at ENDO

Open access

Alessandro Ciresi, Stefano Radellini, Valentina Guarnotta, Maria Grazia Mineo, and Carla Giordano

, NovoNordisk), for measurements of GH. Blood samples for GH were also measured during ITT (0.1 U/kg of body weight of human Humulin R insulin) at baseline and at 30, 60, 90 and 120 min after insulin administration and results were accepted with blood glucose

Open access

Laura van Iersel, Sarah C Clement, Antoinette Y N Schouten-van Meeteren, Annemieke M Boot, Hedi L Claahsen-van der Grinten, Bernd Granzen, K Sen Han, Geert O Janssens, Erna M Michiels, A S Paul van Trotsenburg, W Peter Vandertop, Dannis G van Vuurden, Hubert N Caron, Leontien C M Kremer, and Hanneke M van Santen

.1365-2265.2006.02688.x ) 10 Fleseriu M Hashim IA Karavitaki N Melmed S Murad MH Salvatori R Samuels MH. Hormonal replacement in hypopituitarism in adults: an Endocrine Society Clinical Practice Guideline . Journal of Clinical Endocrinology and