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Agnieszka Pazderska, Yaasir Mamoojee, Satish Artham, Margaret Miller, Stephen G Ball, Tim Cheetham, and Richard Quinton

Not imaged Not imaged Normal Not imaged Preliminary data on patients 1, 4 and 6 were presented in: Santhakumar, A., Miller, M., Quinton, R. Pubertal induction in adult males with isolated hypogonadotropic hypogonadism using long

Open access

Jin Kyu Oh, Young Jae Im, Kwanjin Park, and Jae-Seung Paick

gonadotropin-induced testosterone levels during organogenesis ( 1 ). Among patients with hypogonadotropic hypogonadism, functional deficiencies are more frequently associated with foetal luteinising hormone than with disorders of sexual differentiation. Less

Open access

D Santi, A R M Granata, and M Simoni

about 30% of cases, which fall in the category of ’male idiopathic infertility’ (2) . The medical treatment of infertility may be specific or non-specific. Specific treatments are used for certain etiologies, such as hypogonadotropic hypogonadism, male

Open access

Ichelle Maa van Roessel, Boudewijn Bakker, Hanneke M van Santen, and Wassim Chemaitilly

reported at 7% in a large cohort of CCS ( 47 ). Hypogonadotropic hypogonadism is defined as sex hormone deficit occurring because of hypothalamic–pituitary injury ( 44 ). Up to 4% of children with a brain tumor, not including craniopharyngioma, developed

Open access

Fernanda A Correa, Ericka B Trarbach, Cintia Tusset, Ana Claudia Latronico, Luciana R Montenegro, Luciani R Carvalho, Marcela M Franca, Aline P Otto, Everlayny F Costalonga, Vinicius N Brito, Ana Paula Abreu, Mirian Y Nishi, Alexander A L Jorge, Ivo J P Arnhold, Yisrael Sidis, Nelly Pitteloud, and Berenice B Mendonca

idiopathic hypogonadotropic hypogonadism . PNAS 2007 104 17447 – 17452 . ( doi:10.1073/pnas.0707173104 ). 12 Trarbach EB Costa EM Versiani B de Castro M Baptista MT Garmes HM de Mendonca BB Latronico AC . Novel fibroblast growth factor

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Christian Høst, Anders Bojesen, Mogens Erlandsen, Kristian A Groth, Kurt Kristensen, Anne Grethe Jurik, Niels H Birkebæk, and Claus H Gravholt

.1210/jcem.85.8.6747 ) 16 Yialamas MA Dwyer AA Hanley E Lee H Pitteloud N Hayes FJ . Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism . Journal of Clinical Endocrinology and

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Kristin Ottarsdottir, Anna G Nilsson, Margareta Hellgren, Ulf Lindblad, and Bledar Daka

idiopathic hypogonadotropic hypogonadism . Journal of Clinical Endocrinology and Metabolism 2007 92 4254 – 4259 . ( ) 36 Singh R Artaza JN Taylor WE Gonzalez-Cadavid NF Bhasin S. Androgens stimulate myogenic

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Bruno Donadille, Muriel Houang, Irène Netchine, Jean-Pierre Siffroi, and Sophie Christin-Maitre

cryptorchidism is known to be directly related to altered sperm production, as described in patients with hypogonadotropic hypogonadism ( 26 ). A second hypothesis relies on the fact that Burckhardt’s patient had a severe syndrome including psychomotor

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Rossella Cannarella, Andrea Crafa, Sandro La Vignera, Rosita A Condorelli, and Aldo E Calogero

role of IGF1 in the management of patients with delayed puberty or hypogonadotropic hypogonadism. It is concerning that the evidence in humans is scarce, as the IGF1R knockout is incompatible with life. The human phenotype that is closest to the animal

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Letícia Ribeiro Oliveira, Carlos Alberto Longui, Guilherme Guaragna-Filho, José Luiz Costa, Rafael Lanaro, David Antônio Silva, Maria Izabel Chiamolera, Maricilda Palandi de Mello, André Moreno Morcillo, Andrea Trevas Maciel-Guerra, and Gil Guerra-Junior

hypogonadotropic hypogonadism, gonadal dysgenesis, Leydig cell hypoplasia (LHCGR defect) or defects in testosterone biosynthesis, against the normal or increased testosterone which directs to the molecular investigation of PAIS/CAIS or 5AR2D ( 11 , 12 , 35 , 36