Introduction Type 2 diabetes mellitus (T2DM) is a complex disease characterized by hyperglycemia secondary to inappropriate insulin secretion, resistance to its action, or both. Over time, these alterations and oxidative stress promote the
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Jairo Arturo Pinzón-Cortés, Angelina Perna-Chaux, Nicolás Steven Rojas-Villamizar, Angélica Díaz-Basabe, Diana Carolina Polanía-Villanueva, María Fernanda Jácome, Carlos Olimpo Mendivil, Helena Groot, and Valeriano López-Segura
Hong Wang, Jie Cao, Jian-bin Su, Xue-qin Wang, Dong-mei Zhang, and Xiao-hua Wang
Introduction Individuals with type 2 diabetes (T2D) suffer from an increased risk of thrombotic complications such as myocardial infarction (MI), stroke, and venous thromboembolism (VTE) ( 1 ). Hyperglycemia, increased oxidative stress, and
Taísa A R Vicente, Ívina E S Rocha, Roberto Salvatori, Carla R P Oliveira, Rossana M C Pereira, Anita H O Souza, Viviane C Campos, Elenilde G Santos, Rachel D C Araújo Diniz, Eugênia H O Valença, Carlos C Epitácio-Pereira, Mario C P Oliveira, Andrea Mari, and Manuel H Aguiar-Oliveira
, especially in subjects older than 23 years, with a case of diabetes mellitus (DM) diagnosed in a 38-year-old patient due to βCF exhaustion (7) . However, recently, in a large Ecuadorian study of kindred with Laron syndrome, none of the GH
A V Dreval, I V Trigolosova, I V Misnikova, Y A Kovalyova, R S Tishenina, I A Barsukov, A V Vinogradova, and B H R Wolffenbuttel
glucose anomalies in these patients are now known to include diabetes mellitus (DM), impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) and have been discussed extensively in a review by Colao et al . (2) . Looking more specifically at
Yu Ah Hong, Kyung-Do Han, Jae-Seung Yun, Eun Sil Sil, Seung-Hyun Ko, and Sungjin Chung
Introduction Diabetic nephropathy is a major microvascular complication of type 2 diabetes mellitus (DM), and in many countries of the world, it is the major cause of end-stage renal disease (ESRD) ( 1 , 2 , 3 ). Identification of high
Xiao-jun Zhou, Lin Ding, Jia-xin Liu, Le-qun Su, Jian-jun Dong, and Lin Liao
Introduction Diabetes, as one of the largest global health emergencies in the 21st century, has increased with a burgeoning trend. The latest International Diabetes Federation (IDF) Diabetes Atlas indicated that in 2016 the estimated number of
Punith Kempegowda, Eka Melson, Agnes Johnson, Lucy Wallett, Lucretia Thomas, Dengyi Zhou, Catherine Holmes, Agata Juszczak, Mohammed Ali Karamat, Sandip Ghosh, Wasim Hanif, Parth Narendran, and Srikanth Bellary
Introduction People with diabetes are disproportionately affected by COVID-19. They are more likely to be admitted to the intensive care unit (ICU) compared to those without diabetes ( 1 ). A recent UK cohort study has also demonstrated two
Guang-Ran Yang, Dongmei Li, and Zidian Xie
Introduction Diabetic retinopathy (DR), a typical microvascular complication of diabetes mellitus (DM), is the leading cause of blindness in adult patients aged 20–74 years old in developed countries ( 1 ). In the US, about 4.2 million DM
Alessandra Gambineri and Carla Pelusi
Role of sex and gender on the development of type 2 diabetes There is increasing evidence that sex and gender differences influence the epidemiology, pathophysiology, treatment and outcomes of many diseases, including type 2 diabetes (T2DM
Jing Hong, Wen-Yue Liu, Xiang Hu, Fei-Fei Jiang, Ze-Ru Xu, Fang Li, Fei-Xia Shen, and Hong Zhu
Introduction Diabetic foot disease, a common complication in patients with diabetes mellitus (DM) ( 1 ), is generally associated with a high prevalence of severe macroangiopathic comorbidities that result in high morbidity and mortality ( 2
