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Sarah Zaheer, Kayla Meyer, Rebecca Easly, Omar Bayomy, Janet Leung, Andrew W Koefoed, Mahyar Heydarpour, Roy Freeman, and Gail K Adler

following a bout of intense physical exercise in healthy humans ( 29 , 30 , 31 ). This increase in sclerostin is accompanied by activation of the pituitary–adrenal axis, raising the possibility that acute increases in cortisol due to pituitary

Open access

Milène Tetsi Nomigni, Sophie Ouzounian, Alice Benoit, Jacqueline Vadrot, Frédérique Tissier, Sylvie Renouf, Hervé Lefebvre, Sophie Christin-Maitre, and Estelle Louiset

androgen and cortisol oversecretion is highly suggestive of adrenocortical carcinoma (12) . In very few cases, androgen-secreting adrenal lesions have been identified as bilateral macronodular hyperplasia (13, 14) , adenoma (15) , primary pigmented

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Boni Xiang, Ran Tao, Xinhua Liu, Xiaoming Zhu, Min He, Zengyi Ma, Yehong Yang, Zhaoyun Zhang, Yiming Li, Zhenwei Yao, Yongfei Wang, and Hongying Ye

impairment was relieved after a pituitary implant of 198 Au ( 6 ). Primary cortisol deficiency was reported concomitant with high TSH and low FT3. After cortisone administration, TSH returned to normal. However, serum cortisol and TSH showed no significant

Open access

Henryk F Urbanski, Kevin Mueller, and Cynthia L Bethea

. Blood samples were collected from each animal under ketamine HCl sedation (10 mg/kg body weight, intramuscular), at Month −1 and again at Month 24; the serum was stored frozen at −20°C and subsequently assayed for leptin, cortisol and DHEAS. Note

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Anne-Sophie C A M Koning, Philippe C Habets, Marit Bogaards, Jan Kroon, Hanneke M van Santen, Judith M de Bont, and Onno C Meijer

naturally produced glucocorticoid hormone cortisol. Cortisol also acts via the mineralocorticoid receptor (MR) in many tissues including the brain ( 6 ), but synthetic glucocorticoids have a clear preference for GR over MR ( 7 ). Both receptor types are

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Jonneke J Hollanders, Bibian van der Voorn, Noera Kieviet, Koert M Dolman, Yolanda B de Rijke, Erica L T van den Akker, Joost Rotteveel, Adriaan Honig, and Martijn J J Finken

estriol) and precursor GCs, since the adrenocortical enzymes are not fully matured yet ( 5 ). Subsequently, during the last 6–8 weeks of pregnancy, the more matured fetal adrenal produces increasing amounts of cortisol and cortisone under the control of

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Dorte Glintborg, Magda Lambaa Altinok, Pernille Ravn, Kurt Bjerregaard Stage, Kurt Højlund, and Marianne Andersen

increased ovarian and adrenal androgen production ( 1 ). Adrenocorticotropic hormone (ACTH)-stimulated cortisol and 17-hydroxyprogesterone levels (17OHP) and urinary cortisol secretion were increased in women with PCOS vs controls ( 7 , 8 ), suggesting

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S U Jayasinghe, S J Torres, C A Nowson, A J Tilbrook, and A I Turner

sequential secretion of corticotrophin-releasing hormone (CRH) and arginine vasopressin (AVP) from the hypothalamus, adrenocorticotrophic hormone (ACTH) from the anterior pituitary gland and glucocorticoids such as cortisol from the adrenal cortex (14, 15

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Lisa Arnetz, Neda Rajamand Ekberg, Kerstin Brismar, and Michael Alvarsson

Introduction Along with progressive β-cell failure and insulin resistance, patients with type 2 diabetes (T2D) display disturbed regulation of cortisol and insulin-like growth factor 1 (IGF1) secretion (1) . Especially regarding the hypothalamus

Open access

Pablo Abellán-Galiana, Carmen Fajardo-Montañana, Pedro Riesgo-Suárez, Marcelino Pérez-Bermejo, Celia Ríos-Pérez, and José Gómez-Vela

biochemical criteria ( 8 ). In this respect, cortisol concentration in the immediate postoperative period has been the most widely used long-term prognostic indicator in most of the published series ( 1 , 4 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ). The