: puberty onset and progression, testicular volume, gonadotropin, and total testosterone serum levels, sperm parameters and fertility, micropenis. Methods Sources Data used to perform this systematic review were independently extracted by A C and
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Rossella Cannarella, Andrea Crafa, Sandro La Vignera, Rosita A Condorelli, and Aldo E Calogero
Rajae Talbi and Victor M Navarro
potentially regulate metabolism (discussed in later sections), and (2) Kiss1 AVPV/PeN neurons to regulate fertility ( 10 , 11 ). An additional population of Kiss1 neurons has been recently identified in the posterodorsal part of the medial amygdala (Kiss1
Bruno Donadille, Muriel Houang, Irène Netchine, Jean-Pierre Siffroi, and Sophie Christin-Maitre
is metabolised through CYP11B1 activity, the absence of 11OHA4 is in accordance with a complete 3b-HSD deficit ( 22 ). Therefore, testosterone in our patient probably originates from testicular production. Fertility of male patients with HSD3B2
André Marques-Pinto and Davide Carvalho
. Consistent detection of ED residues in human serum, seminal plasma and follicular fluid has raised concern that environmental exposure to ED is affecting human fertility (24) . Though ED are not considered major teratogens, reproductive function – from
Neil R Chappell, Beth Zhou, Amy K Schutt, William E Gibbons, and Chellakkan S Blesson
the lean PCOS mouse model, 8-week-old C57/Bl6 female mice ( n = 26) were mated with males of proven fertility. Copulatory plugs were visualized to confirm mating on the following morning, which was considered day 0.5. Pregnant dams were injected with
Anita Hokken-Koelega, Aart-Jan van der Lely, Berthold Hauffa, Gabriele Häusler, Gudmundur Johannsson, Mohamad Maghnie, Jesús Argente, Jean DeSchepper, Helena Gleeson, John W Gregory, Charlotte Höybye, Fahrettin Keleştimur, Anton Luger, Hermann L Müller, Sebastian Neggers, Vera Popovic-Brkic, Eleonora Porcu, Lars Sävendahl, Stephen Shalet, Bessie Spiliotis, and Maithé Tauber
publications to ensure adherence. Fertility in these patients is an important issue and the consensus was to begin discussions with patients beginning around ages 11–12 years, depending on their maturity level, using simple terms. Additional specialists, i
Shota Dzemaili, Jitske Tiemensma, Richard Quinton, Nelly Pitteloud, Diane Morin, and Andrew A Dwyer
induce secondary sexual characteristics and menses ( 4 ). Combined gonadotropin therapy or physiologic treatment with pulsatile GnRH are equally effective for inducing fertility in the vast majority of cases ( 10 ). Compared to fertile counterparts
Sidsel Mathiesen, Kaspar Sørensen, Marianne Ifversen, Casper P Hagen, Jørgen Holm Petersen, Anders Juul, and Klaus Müller
prolonged follow-up should, therefore, be recommended for all patients. Prediction of fertility is an even more critical issue after pediatric HSCT. For patients being prepubertal at HSCT, higher FSH levels and lower inhibin B levels were associated with
Lukas Ochsner Ridder, Agnethe Berglund, Kirstine Stochholm, Simon Chang, and Claus H Gravholt
, most likely related to consultations in fertility clinics. The fertility rate among 47,XYY is higher than in KS, likely resulting in the identification of fewer cases through young adult years. An estimated 87% of KS patients have the 47,XXY karyotype
Jens F Rehfeld
germ cells as putative fertility factors, in cardiac myocytes for unknown reasons, and in immune cells of significance for inflammatory diseases. Finally, the proCCK maturation appears to be cell specific also in tumors expressing the CCK gene. The
