immediately performed, were frozen and stored at −80°C. For analyses, commercially available ELISA or multiplex kits were used: glucagon and glicentin (Mercodia, Uppsala, Sweden); total glucagon-like peptide (GLP)-1 (7-36 and 9-36) and total glucose
Search Results
Giovanni Fanni, Petros Katsogiannos, Bipasha Nandi Jui, Magnus Sundbom, Susanne Hetty, Maria J Pereira, and Jan W Eriksson
Kim K B Clemmensen, Jonas S Quist, Dorte Vistisen, Daniel R Witte, Anna Jonsson, Oluf Pedersen, Torben Hansen, Jens J Holst, Torsten Lauritzen, Marit E Jørgensen, Signe Torekov, and Kristine Færch
). Additionally, the time of the day of an OGTT seems to influence the glucose response with higher post-load blood glucose levels in the afternoon and evening compared to the morning ( 1 , 3 ). The incretin hormones glucagon-like peptide 1 (GLP-1) and glucose
Shin-ya Ueda, Hidehiro Nakahara, Eriko Kawai, Tatsuya Usui, Shintaro Tsuji, and Tadayoshi Miyamoto
glucagon-like peptide-1 (GLP-1), peptide YY (PYY) and ghrelin ( 2 ). The effects of exercise on these hormones have been investigated extensively over the past decade ( 3 , 4 ). Previous findings suggested that the concentrations of anorexigenic hormones
Lili Liu, Zhuo Shao, Ying Xia, Jiabi Qin, Yang Xiao, Zhiguang Zhou, and Zubing Mei
. Incretin-based drugs, including glucagon-like peptide 1 receptor agonists (GLP-1 RAs) and dipeptidyl peptidase 4 (DPP-4) inhibitors, may offer an opportunity to avoid these side effects. Theoretically, GLP-1 RAs are structurally and functionally similar to
Lizhi Zhang, Jinwei He, Xiang Sun, Dongyue Pang, Jingjing Hu, and Bo Feng
). Some drugs commonly used to regulate blood sugar, such as glucagon-like peptide-1 (GLP-1) receptor agonists and DPP-4 inhibitors (DPP-4is), can inhibit bone resorption and improve bone formation ( 2 , 3 , 4 , 5 , 6 , 7 ). GLP-1 is a DPP-4 substrate
Amalie R Lanng, Lærke S Gasbjerg, Natasha C Bergmann, Sigrid Bergmann, Mads M Helsted, Matthew P Gillum, Bolette Hartmann, Jens J Holst, Tina Vilsbøll, and Filip K Knop
). Likewise, the effect of alcohol on the secretion of the gut-derived insulinotropic incretin hormones, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) remains unclear ( 6 , 11 , 12 ). Recently, alcohol was shown to
Agnieszka Kosowska, Enrique Gallego-Colon, Wojciech Garczorz, Agnieszka Kłych-Ratuszny, Mohammad Reza F Aghdam, Michał Woz´niak, Andrzej Witek, Agnieszka Wróblewska-Czech, Anna Cygal, Jerzy Wojnar, and Tomasz Francuz
mechanism of action of incretin mimetic drugs is through the binding to glucagon-like peptide-1 receptor (GLP-1R) in pancreatic beta cells stimulating insulin secretion. The two most important natural incretin hormones are glucagon-like peptide-1 (GLP-1) and
M Jensterle, A Podbregar, K Goricar, N Gregoric, and A Janez
almost exclusively due to loss of body fat ( 6 ). In selected patients, TRT could be started concomitantly or in addition to LSM to augment the benefits of LSM, although the quality of evidence supporting this concept is low ( 2 ). GLP1 receptor
Henri Honka, Jukka Koffert, Saila Kauhanen, Nobuyuki Kudomi, Saija Hurme, Andrea Mari, Andreas Lindqvist, Nils Wierup, Riitta Parkkola, Leif Groop, and Pirjo Nuutila
incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) account for the gut-derived amplification of insulin secretion ( 4 ). In addition to the effect on pancreatic islets, we ( 5 ) and others ( 6 ) have
Signe Frøssing, Malin Nylander, Caroline Kistorp, Sven O Skouby, and Jens Faber
agonists (GLP-1RA) were developed for treatment of hyperglycemia in T2D, but have additionally weight-reducing effect and have proven effective in smaller studies in women with PCOS ( 19 ). The LEADER study in high-risk patients with T2D reported that the
