inhibin B and undetectable total testosterone (TTe) levels ( Table 1 ). He was normosmic at Brief-Smell Identification test (B-SIT) and normal central olfactory structures were confirmed using MRI. His karyotype was 46,XY. At the age of 15 years, he
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Elena Galazzi, Paolo Duminuco, Mirella Moro, Fabiana Guizzardi, Nicoletta Marazzi, Alessandro Sartorio, Sabrina Avignone, Marco Bonomi, Luca Persani, and Maria Teresa Bonati
Sebastião Freitas de Medeiros, Márcia Marly Winck Yamamoto, Matheus Antônio Souto de Medeiros, Bruna Barcelo Barbosa, José Maria Soares Junior, and Edmund Chada Baracat
, 33 ). Biochemical hyperandrogenism was defined by at least one of the following criteria: total testosterone ≥2.1 nmol/L, free testosterone (FT)≥0.03 pmol/L, dehydroepiandrosterone sulfate (DHEAS) ≥6.7 µmol/L, androstenedione (A4) ≥8.6 nmol/L, and
Zofia Kolesinska, James Acierno Jr, S Faisal Ahmed, Cheng Xu, Karina Kapczuk, Anna Skorczyk-Werner, Hanna Mikos, Aleksandra Rojek, Andreas Massouras, Maciej R Krawczynski, Nelly Pitteloud, and Marek Niedziela
testosterone were measured by radioimmunoassays: Active Androstenedione RIA (Beckman Coulter, Immunotech) and TESTO-RIA-CT (DIAsource ImmunoAssays S.A., Belgium), respectively. Anti-Müllerian hormone (AMH) and inhibin B were evaluated by ELx800 Absorbance
Estelle Bonnet, Mathias Winter, Delphine Mallet, Ingrid Plotton, Claire Bouvattier, Maryse Cartigny, Laetiti Martinerie, Michel Polak, Anne Bachelot, Frédéric Huet, Sabine Baron, Muriel Houang, Sylvie Soskin, Anne Lienhardt, Jérôme Bertherat, Cyril Amouroux, Aurore Bouty, Lise Duranteau, Rémi Besson, Alaa El Ghoneimi, Dinane Samara-Boustani, François Becmeur, Nicolas Kalfa, Françoise Paris, François Medjkane, Aude Brac de la Perrière, Patricia Bretones, Hervé Lejeune, Marc Nicolino, Pierre Mouriquand, Daniela-Brindusa Gorduza, and Claire-Lise Gay
determination of the testosterone/DHT ratio (elevated at baseline and/or after human chorionic gonadotrophin (hCG) stimulation test in SRD5A2 deficiency) and of the testosterone/androstenedione ratio (low at baseline and after hCG stimulation test in HSD17B3
Nafiye Helvaci, Erdem Karabulut, Ahmet Ugur Demir, and Bulent Okan Yildiz
of total and free testosterone, fasting glucose and fasting insulin. Statistical analysis Meta-analysis was performed using metafor package, version 1.9–5 in R 3.1.2 software. Freeman–Tukey double arcsine transformation that provides the
Shilpa Lingaiah, Laure Morin-Papunen, Terhi Piltonen, Inger Sundström-Poromaa, Elisabet Stener-Victorin, and Juha S Tapanainen
/ASRM) consensus definition ( 25 ). Ovarian morphology was assessed by means of transvaginal ultrasonography in all subjects. Biochemical hyperandrogenism was defined as serum testosterone ≥2.3 nmol/L, according to the upper limits of the accredited laboratory at
Brendan J Nolan, Aviva S Frydman, Shalem Y Leemaqz, Meg Carroll, Mathis Grossmann, Jeffrey D Zajac, and Ada S Cheung
more rapid feminisation with greater testosterone suppression and enhanced breast development ( 2 ), however, others raise concerns regarding breast cancer and cardiovascular disease risk with the use of progestins ( 3 ). Due to a lack of evidence
Stavroula A Paschou, Eleni Palioura, Dimitrios Ioannidis, Panagiotis Anagnostis, Argyro Panagiotakou, Vasiliki Loi, Georgios Karageorgos, Dimitrios G Goulis, and Andromachi Vryonidou
, insulin, total testosterone (TT), Δ4-androstenedione (Δ4A), dehydroepiandrosterone sulfate (DHEA-S) and sex hormone-binding globulin (SHBG) were assessed in the early follicular phase of the menstrual cycle. Homeostatic model assessment-insulin resistance
Iben Katinka Greiber, Casper P Hagen, Alexander Siegfried Busch, Mikkel Grunnet Mieritz, Lise Aksglæde, Katharina Main, Kristian Almstrup, and Anders Juul
), estradiol (318 girls: 920; 658 boys: 1405) and testosterone (319 girls: 930; 658 boys: 1405). Genotyping Peripheral blood (EDTA-preserved) was used for isolation of genomic DNA using the QuickGene-810 Nucleic Acid Isolation System (Fujifilm, Life
R Walia, M Singla, K Vaiphei, S Kumar, and A Bhansali
hormone (LH), follicle-stimulating hormone (FSH), testosterone (T) and dihydrotestosterone (DHT), androstenedione (A) and unstimulated and/or stimulated 17-hydroxy progesterone 17(OH) P levels (where indicated). Congenital adrenal hyperplasia was diagnosed