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Xiaoya Zheng, Heng Xiao, Jian Long, Qiang Wei, Liping Liu, Liping Zan, and Wei Ren

is that the number of patients included is relatively small, and the event rate is accordingly low, thereby limiting the power and reliability of the statistical analysis. It is difficult to draw a statistically significant conclusion if a subgroup

Open access

Mabel E Bohórquez, Ana P Estrada, Jacob Stultz, Ruta Sahasrabudhe, John Williamson, Paul Lott, Carlos S Duque, Jorge Donado, Gilbert Mateus, Fernando Bolaños, Alejandro Vélez, Magdalena Echeverry, and Luis G Carvajal-Carmona

and Chinese populations, we failed to replicate association between HABP2 G534E and TC risk in Hispanic population as well. We, however, acknowledge that our study may have limited power to detect the low-penetrance effect of a variant that is

Open access

Thozhukat Sathyapalan, Anne-Marie Coady, Eric S Kilpatrick, and Stephen L Atkin

PCOS ( 11 , 26 ). For 90% power, significance level of 5% and adjusting for a possible 20% dropout rate, 20 subjects were enrolled in each group. Comparisons between both the groups from baseline were carried out using the paired t test for

Open access

Myrtille Fouché, Yves Bouffard, Mary-Charlotte Le Goff, Johanne Prothet, François Malavieille, Pierre Sagnard, Françoise Christin, Davy Hayi-Slayman, Arnaud Pasquer, Gilles Poncet, Thomas Walter, and Thomas Rimmelé

postoperative complications. Thus, the impact of ioCS on outcomes, as Condron and Massimino et al. reported was not feasible ( 19 , 21 ). In addition, a lack of power due to the relatively small sample size did not facilitate the identification of ioCS risk

Open access

Anne Jouinot, Bernard Royer, Etienne Chatelut, Sotheara Moeung, Guillaume Assié, Audrey Thomas-Schoemann, Jérôme Bertherat, François Goldwasser, and Benoit Blanchet

sample size, which limits the statistical power and the generalization of the results. Especially, data on etoposide clearance after mitotane discontinuation derived from a single patient. Further studies with larger cohorts are needed to confirm these

Open access

David Koeckerling, Jeremy W Tomlinson, and Jeremy F Cobbold

limited. Controlled studies with sufficient statistical power to outline exercise programmes or physical activity guidelines tailored to NAFLD patients are lacking ( 64 ). Mechanisms underlying proposed benefits of exercise in NAFLD pertain to improvements

Open access

Suvanjaa Sivalingam, Marianne Thvilum, Thomas Heiberg Brix, Laszlo Hegedüs, and Frans Brandt

impact of month of birth for the development of GD has only received little attention ( 18 , 19 ). Due to low power, the findings have been inconclusive. In contrast to GD, it has never been investigated whether TNG is influenced by seasonality in month

Open access

Nassim Ghaffari-Tabrizi-Wizsy, Christina Angelika Passegger, Laura Nebel, Fabian Krismer, Gudrun Herzer-Schneidhofer, Gert Schwach, and Roswitha Pfragner

least prior to work with mouse system ( Fig. 5 ). Therefore, CAM assay could serve as a preclinical tool for seeking drugs against MTC and might help to increase the power and speed of the development of new drugs. Figure 5 Chick before the mouse

Open access

Keina Nishio, Akiko Tanabe, Risa Maruoka, Kiyoko Nakamura, Masaaki Takai, Tatsuharu Sekijima, Satoshi Tunetoh, Yoshito Terai, and Masahide Ohmichi

patients. The average serum BAP was not significantly elevated in the OC and EC groups; however, the power of this study to detect a significant difference was limited. These differences may be significant if a larger number of subjects were analyzed

Open access

Ulrik Ø Andersen, Dijana Terzic, Nicolai Jacob Wewer Albrechtsen, Peter Dall Mark, Peter Plomgaard, Jens F Rehfeld, Finn Gustafsson, and Jens P Goetze

:// ) 18 Power DM Bunnett N Turner AJ Dimaline R . Degradation of endogenous heptadecapeptide gastrin by endopeptidase 24.11 in the pig . American Journal of Physiology 1987 253 G33 – G39 . ( https