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Yael Sofer, Nava Nevo, Michal Vechoropoulos, Gabi Shefer, Etty Osher, Nathan Landis, Karen Tordjman, Geoffrey L Hammond, and Naftali Stern

steroids, and it has been traditionally postulated that the role of SHBG is limited to the transport of sex steroids into the target cells ( 2 , 3 ). However, it has also been reported that SHBG interacts with a trans-membrane receptor that activates

Open access

Emma Jernberg, Anders Bergh, and Pernilla Wikström

point mutations generally affect the c-terminal LBD, while about one-third occur in the transactivating NTD ( 29 , 30 ) resulting in broaden ligand specificity and AR activation by weak adrenal androgens and other steroid hormones, including DHEA

Open access

Barbara J Boucher

O & Hocher B . Impact of vitamin D on pregnancy-related disorders and on offspring outcome . Journal of Steroid Biochemistry and Molecular Biology 2018 180 51 – 64 . ( ) 8 Spaight C , Gross

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Ruth Percik, Sherwin Criseno, Safwaan Adam, Kate Young, and Daniel L Morganstein

steroids have been used, then standard approaches to weaning should be followed, but if after a prolonged period there has been no recovery of endogenous cortisol production, then the possibility of co-existent ACTH deficiency should be considered. Hence

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Mirjana Kocova, Vesna Janevska, and Violeta Anastasovska

of patients with a homozygous p.I172N mutation causing the SV form of the disease with enzyme activity up to 2% ( 6 , 20 , 14 , 17 ). However, isolated cases with 11-hydroxylase and 3b-hydroxyl steroid dehydrogenase gene mutations as well as rare

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Siphiwe N Dlamini, Zané Lombard, Lisa K Micklesfield, Nigel Crowther, Shane A Norris, Tracy Snyman, Andrew A Crawford, Brian R Walker, and Julia H Goedecke

medications for elevated blood pressure and diabetes were also considered as relevant indicators of the presence of elevated blood pressure and fasting blood glucose concentrations, respectively. Steroid extraction and glucocorticoid measurements

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B Fabre, G Maccallini, A Oneto, D Gonzalez, V Hirschler, C Aranda, and G Berg

tear fluid for diagnostic purposes . Annales de Biologie Clinique 1993 51 903 – 910 . 4 Riad Fahmy D Read GF Walker RF Griffiths K . Steroids in saliva for assessing endocrine function . Endocrine Reviews 1982 3 367 – 395 . ( doi

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Jakub Supronik, Małgorzata Szelachowska, Adam Kretowski, and Katarzyna Siewko

-to-severe GO ( 21 , 22 , 23 ). Lastly, a second course of ivGC treatment or teleradiotherapy in combination with i.v. or oral steroids may be of benefit in selected patients as a second line of therapy. Nevertheless, studies provide only limited evidence to

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Ramjan Sanas Mohamed, Biyaser Abuelgasim, Sally Barker, Hemanth Prabhudev, Niamh M Martin, Karim Meeran, Emma L Williams, Sarah Darch, Whitlock Matthew, Tricia Tan, and Florian Wernig

were advised to avoid smoking, drinking alcohol or coffee for 2 h before sample collection. Steroid-containing skin creams were to be avoided, and patients were advised to wash their hands before collection. Some patients gave their saliva samples while

Open access

Marcus Quinkler, Bertil Ekman, Claudio Marelli, Sharif Uddin, Pierre Zelissen, Robert D Murray, and on behalf of the EU-AIR Investigators

glucocorticoid replacement therapy in AI ( 13 ). Recent data, however, suggest that prednisolone is deleterious for bone mineral density in AI ( 17 , 19 , 33 , 34 ). Few comparative data with hydrocortisone for additional steroid-dependent end points are