Search Results

You are looking at 71 - 80 of 207 items for

  • Refine by Access: All content x
Clear All Modify Search
Open access

Kerry V Fanson, Tamara Keeley, and Benjamin G Fanson

Introduction Elevated glucocorticoid (GC) titers associated with chronic stress can lead to reproductive failure (1) . Consequently, studies of reproductive dysfunction often focus on the suppressive effects of GCs. However, GCs also play a

Open access

A Daniel Bird, Spencer Greatorex, David Reser, Gareth G Lavery, and Timothy J Cole

Introduction The short-chain alcohol dehydrogenase/reductase enzymes 11βHSD1 and 11βHSD2 play important intracellular roles in mammals, regulating tissue availability of physiologically relevant glucocorticoid ( 1 , 2 ). They are members of

Open access

Amir Bashkin, Eliran Yaakobi, Marina Nodelman, and Ohad Ronen

glucocorticoids, levothyroxine, Mercaptizol, Propylthiouracil, Amiodarone, opioids and drugs that enhance T4 metabolism through the enhancement of cytochrome P450 3A4 such as phenytoin and carbamazepine ( 5 , 6 ). Patients were divided into the following

Open access

Hong Jiang, WenJie Yang, QingFang Sun, Chang Liu, and LiuGuan Bian

mineralocorticoid receptors (MRs), to which both mineralocorticoids and glucocorticoids can bind ( 20 ). Experimental animal studies have already demonstrated the neurotoxic effects of hypercortisolism on the limbic system ( 21 ). Previous studies of CD patients

Open access

Shane M Regnier, Andrew G Kirkley, Daniel Ruiz, Wakanene Kamau, Qian Wu, Kurunthachalam Kannan, and Robert M Sargis

have shown that TF augments adipogenesis in vitro ( 18 ) and promotes insulin resistance in rodent and human adipose tissues exposed ex vivo ( 19 ). These effects are postulated to result from activation of adipocytic glucocorticoid receptor (GR

Open access

Xiaolei Hu and Fengling Chen

Sulfonylurea/α-glucosidase inhibitor 65 Lispro 64 Glulisine 8 , 74 Glargine 42 Glucocorticoids 75 , 76 , 77 Immunosuppressants 6 , 17 , 78 Immunosuppressive 79 Medical

Open access

Stephanie Burger-Stritt, Linda Bachmann, Max Kurlbaum, and Stefanie Hahner

replacement at times of increased requirement. To avoid AC, patients are educated in adaptation of their glucocorticoid (GC) dose under stressful conditions ( 12 , 13 , 14 ). AC requires immediate initiation of parenteral administration of GCs ( 13 , 14

Open access

Johanna Christina Penell, Mark M Kushnir, Lars Lind, Jonatan Bergquist, Jonas Bergquist, P Monica Lind, and Tord Naessen

( n  = 3, all women), persons on hormone replacement therapy ( n women  = 243, n men = 19) and persons on glucocorticoid therapy ( n women = 6, n men = 4). Statistical significant difference between men and women as evaluated by chi

Open access

Arno Téblick, Lies Langouche, and Greet Van den Berghe

important systems requiring adequate levels of cortisol for normal functioning include the immune system, cardiovascular system, fluid and electrolyte homeostasis. Cortisol exerts its effects by binding to the intracellular glucocorticoid receptor (GR

Open access

Efstratios Kardalas, Stavroula A Paschou, Panagiotis Anagnostis, Giovanna Muscogiuri, Gerasimos Siasos, and Andromachi Vryonidou

hyperaldosteronism • Rare renin-secreting tumors • Glucocorticoid-remediable congenital adrenal hyperplasia. • Ingestion of substances such as glycyrrhizin • Bartter syndromeGitelman syndrome Liddle syndrome • Renal tubular acidosis Fanconi syndrome