filtration rate >70 ml/min per 1.73 m 2 . The primary outcome of the study was the comparison of the circadian rhythm of plasma and salivary cortisol. Exclusions included diabetes mellitus, subjects on oral corticosteroid preparations, pregnant women (serum
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Hershel Raff and Hariprasad Trivedi
Ziting Liang, Mengge Yang, Changjuan Xu, Rong Zeng, and Liang Dong
increased risk of diabetes mellitus (DM) due to the sedentary lifestyle and adiposity of COPD patients, the inflammatory processes ( 2 ), and the treatment adverse effects associated with the use of high-dose corticosteroids ( 3 ). On the other hand
Jaafar Jaafar, Eugenio Fernandez, Heba Alwan, and Jacques Philippe
corticosteroids) Nivolumab Hypothyroidism 2–3 month (range 1 day–16.6 month) Frequently stay in hypothyroidism with long-term THR Pembrolizumab Hyperthyroidism 1.4 month (range: 1 day to ~22 month) Three-fourths of affected patients 2
Arno Téblick, Lies Langouche, and Greet Van den Berghe
referred to as ‘relative adrenal insufficiency’, this state is nowadays labeled ‘critical illness-related corticosteroid insufficiency’ (CIRCI). In contrast to the occurrence of absolute adrenal failure in critically ill patients, neither a clear definition
Paraskevi Kazakou, Stavroula A Paschou, Theodora Psaltopoulou, Maria Gavriatopoulou, Eleni Korompoki, Katerina Stefanaki, Fotini Kanouta, Georgia N Kassi, Meletios-Athanasios Dimopoulos, and Asimina Mitrakou
secretion (11, 69) Drugs (corticosteroids, antivirals) (11, 34) Cahexia, muscle weakness, rhabdomyolysis lead to decreased insulin sensitivity (35, 36, 37) DPP4 potential SARS-CoV-2 receptor (70, 71, 72, 73) Hypothalamus and pituitary Possible
Jakub Supronik, Małgorzata Szelachowska, Adam Kretowski, and Katarzyna Siewko
patients (12 in the placebo arm and 13 in the RTX arm), 21 completed the primary endpoint of 24 weeks and 19/21 completed the 52-week observation. Both groups were similar at baseline with regard to age, sex, smoking status, prior corticosteroid treatment
Legh Wilkinson, Nicolette J D Verhoog, and Ann Louw
systemic administration of potent corticosteroid ( 61 ) Systemic lupus erythematosus (SLE) PBMCs Reduced N.D Diminished GC sensitivity ( 62 , 63 , 64 ) Inflammatory bowel disease (IBD) PBMCs Reduced N.C Impaired
Kathrin R Frey, Tina Kienitz, Julia Schulz, Manfred Ventz, Kathrin Zopf, and Marcus Quinkler
-sectional outpatient study . Bone 2006 39 253 – 259 . ( https://doi.org/10.1016/j.bone.2006.02.005 ) 16574519 10.1016/j.bone.2006.02.005 3 Heureux F Maiter D Boutsen Y Devogelaer JP Jamart J Donckier J . Evaluation of corticosteroid replacement
Jonneke J Hollanders, Bibian van der Voorn, Noera Kieviet, Koert M Dolman, Yolanda B de Rijke, Erica L T van den Akker, Joost Rotteveel, Adriaan Honig, and Martijn J J Finken
trimester, (5) use of systemic corticosteroids during pregnancy, (6) if participating in this study would interfere with regular care or (7) use of psychotropic medication. The study was approved by the medical ethics committees of the OLVG West Hospital
B Shahida, P Sahlstrand Johnson, R Jain, H Brorson, P Åsman, M Lantz, and T Planck
. All patients had been treated with corticosteroids ( Table 1 ). The tissue was cut into pieces of 1–3 mm, trypsinized and cultured in DMEM with 10% FBS and 1% penicillin-streptomycin (Gibco, Thermo Scientific). The medium was changed every third day